Catalyst News and Research

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Breakthrough in mirror molecule synthesis opens doors for drug discovery

A University of Texas at Dallas chemist and his colleagues have developed a new chemical reaction that will allow researchers to synthesize selectively the left-handed or right-handed versions of "mirror molecules" found in nature and assess them for potential use against cancer, infection, depression, inflammation and a host of other conditions.

10 Oct 2024

Catholic hospital offered bucket, towels to woman it denied an abortion, California AG said

When Anna Nusslock showed up at her local hospital 15 weeks pregnant and in severe pain earlier this year, she said, a doctor delivered devastating news: The twins she and her husband had so desperately wanted were not viable.

7 Oct 2024

How Minnesota figures into the presidential politics of insulin prices

In June 2019, Lija Greenseid handed Minnesota Gov. Tim Walz an empty vial of insulin that her 13-year-old daughter had painted gold.

1 Oct 2024

University of Texas MD Anderson Cancer Center launches new journal on cancer education

The University of Texas MD Anderson Cancer Center today announced its first-ever academic journal, Advances in Cancer Education & Quality Improvement (ACE-QI). The journal will publish research, training program summaries and quality improvement interventions for the oncology provider community.

27 Sep 2024

New AI tool revolutionizes drug discovery for rare diseases

There are more than 7,000 rare and undiagnosed diseases globally.

25 Sep 2024

Digital health investment could save millions from noncommunicable diseases

An investment today of an additional US$0.24 per patient per year in digital health interventions, such as telemedicine, mobile messaging and chatbots, can help save more than 2 million lives from noncommunicable diseases over the next decade, says a new report released jointly by the World Health Organization (WHO) and ITU (International Telecommunication Union).

23 Sep 2024

Genetic analysis challenges the idea that loneliness directly causes diseases

Research reveals that loneliness is linked to numerous diseases observationally, but genetic analysis shows it's likely a marker rather than a cause.

18 Sep 2024

New discovery offers hope for overcoming CAR-T cell therapy resistance

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

12 Sep 2024

Sally Ross Soter donates $15 million to advance women’s heart health

Cardiovascular disease is the leading cause of death for women, and gaps in care and access persist between women and men.

9 Sep 2024

NIDDK Catalyst Award funds research on mammary gland's role in metabolic diseases

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Catalyst Award program has awarded a $4 million, five-year grant to Prashant Rajbhandari, PhD, Assistant Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at the Mount Sinai Diabetes, Obesity, and Metabolism Institute, to investigate a new frontier in understanding metabolic diseases like obesity and type 2 diabetes.

27 Aug 2024

Disability rights activist pushes government to let him participate in society

Garret Frey refuses to be sidelined. Frey has been paralyzed from the neck down for more than 37 of his 42 years. He has spent decades rejecting the government's excuses when he and others with disabilities are denied the support they need to live in their own homes and to participate in society.

23 Aug 2024

Exploring the impact of thyroid hormone on brain function

Thyroid hormone plays a key role in regulating a range of physiologic functions, including metabolism, temperature, heart rate, and growth. It accomplishes this impressive array of activities by interacting with almost every organ system in the body. Yet despite a long history of research on how thyroid hormone influences different organs, its effects on arguably the most crucial organ -; the brain -; have remained shrouded in mystery.

23 Aug 2024

Study reveals distinct long COVID patterns in children and adolescents

Scientists investigating long COVID in youth found similar but distinguishable patterns between school-age children (ages 6-11 years) and adolescents (ages 12-17 years) and identified their most common symptoms.

21 Aug 2024

MedPearl enhances productivity and referral quality for primary care clinicians

Data published today in the New England Journal of Medicine Catalyst reported that MedPearl, a Providence-developed clinician-built clinical decision platform, improves primary care clinician productivity, decreases time waste on administrative tasks and improves the quality of referrals sent to specialists.

21 Aug 2024

Gamified workplace wellness program boosts employee health and wellbeing

Corporate Cup, lunchtime yoga, or even 'walk and talks', organizations come up with all sorts of wellness initiatives to encourage people to be more active in the workplace.

20 Aug 2024

PINNACLE AI model advances protein analysis in real-world contexts

A fish on land still waves its fins, but the results are markedly different when that fish is in water. Attributed to renowned computer scientist Alan Kay, the analogy is used to illustrate the power of context in illuminating questions under investigation.

16 Aug 2024

Common oral antibiotics tied to increased risk of severe drug-induced rashes

Two classes of commonly prescribed oral antibiotics are associated with the greatest risk for severe drug rashes that can lead to emergency department visits, hospitalizations and even death, according to a new study.

8 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression.

7 Aug 2024

Sanders-Brown Center on Aging unveils new program to boost brain health for dementia patients, caregivers

The University of Kentucky's Sanders-Brown Center on Aging has introduced a groundbreaking initiative, Brain Health Activities, aimed at supporting individuals with dementia and their caregivers.

5 Aug 2024