Cell Development News and Research

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T-cells can develop in human tonsils

A new study provides evidence that a critical type of immune cell can develop in human tonsils. The cells, called T lymphocytes, or T cells, have been thought to develop only in the thymus, an organ of the immune system that sits on the heart.

6 Mar 2012

New breakthrough in early mammalian embryo development

Pioneering work by a leading University of Nottingham scientist has helped reveal for the first time a vital process in the development of the early mammalian embryo.

3 Mar 2012

Scientists observe maturation of immune cells in live zebrafish embryos

T-cells are the immune system's security force. They seek out pathogens and rogue cells in the body and put them out of action. Their precursors are formed in the bone marrow and migrate from there into the thymus. Here, they mature and differentiate to perform a variety of tasks. Scientists at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg have now succeeded for the first time in observing the maturation of immune cells in live zebrafish embryos.

17 Feb 2012

Study reveals new guiding principles for cancer genomics

That our chromosomes can break and reshuffle pieces of themselves is nothing new; scientists have recognized this for decades, especially in cancer cells. The rules for where chromosomes are likely to break and how the broken pieces come together are only just now starting to come into view.

17 Feb 2012

New technology helps scientists observe Parkinson's cell development

In the US alone, at least 500,000 people suffer from Parkinson's disease, a neurological disorder that affects a person's ability to control his or her movement. New technology from the University of Bonn in Germany lets researchers observe the development of the brain cells responsible for the disease.

1 Feb 2012

SENP1 prevents STAT5 from becoming trapped in nucleus

When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports today in Molecular Cell.

30 Jan 2012

First details of genetic alterations that fuel early T-cell precursor ALL

Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The findings from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP) highlight a possible new strategy for treating patients with this more aggressive cancer.

12 Jan 2012

Damon Runyon Cancer Research Foundation names 18 new Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 18 new Damon Runyon Fellows at its fall Fellowship Award Committee review.

11 Jan 2012

MAL3-101 appears to have potent anti-tumor effects on multiple myeloma

A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, a bone marrow cancer.

10 Jan 2012

Amyloid precursor protein fragment may be a biomarker for autism

Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry and the Silver Child Development Center.

4 Jan 2012

Shorter Chk1 protein neutralizes longer sibling to potentially benefit cancer patients

Scientists have found at least one instance when the smaller sibling gets to call the shots and cancer patients may one day benefit.

4 Jan 2012

Researchers identify molecules that can stimulate heart muscle regeneration

Damaged heart tissue is not known for having much inherent capacity for repair. But now, scientists are closing in on signals that may be able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of molecules that can stimulate stem cells to develop into beating heart muscle cells.

23 Dec 2011

Researchers discover molecular marker for immediate precursors of blood stem cells

A research team led by Nancy Speck, PhD, professor of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, has discovered a molecular marker for the immediate precursors of hematopoietic (blood) stem cells (HSCs) in the developing embryo, which provides much-needed insights for making these cells from engineered precursors.

9 Dec 2011

Research: lncRNA affects apoptosis and plays a role in RBC development

A long non-coding RNA (lncRNA) regulates programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. This is the first time a lncRNA has been found to play a role in red blood cell development and the first time a lncRNA has been shown to affect programmed cell death.

8 Dec 2011

Four PhD graduates to showcase cutting-edge research in University of Leicester lectures

The University of Leicester has announced its upcoming Doctoral Inaugural Lectures for 2011, which celebrate and showcase four doctoral graduates who are both outstanding academically and able to present their work in a way that is accessible and engaging. The speakers will talk about their doctoral research, with subjects including: personalising asthma prescriptions, understanding growth disorders of bodily organs, building models of human brain function and defining the mechanisms of pollen fertility in plants.

30 Nov 2011

Study reveals underlying molecular mechanism contributing to development of lymphomagenesis

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have discovered a new potential therapeutic target for Diffuse Large B-Cell Lymphoma (DLBCL), the most aggressive and common type of lymphoma in adults.

29 Nov 2011

CUMC presents 2011 Naomi Berrie Award to UMDNJ researcher

Columbia University Medical Center (CUMC) presented the 2011 Naomi Berrie Award to Barry E. Levin, MD, a University of Medicine & Dentistry of New Jersey researcher whose work focuses on the mechanisms by which specialized metabolic-sensing neurons regulate glucose and energy homeostasis. Junior investigator Kazuhisa Watanabe, at Columbia University Medical Center, received a Berrie Fellow award.

22 Nov 2011

Scientists search for main culprit behind Sj-gren's syndrome

Researchers want to find the main culprit behind the dry, irritated eyes, mouth, throat, skin, nose and more afflicting 1-3 percent of the population.

22 Nov 2011

Swissmedic approves REVLIMID for treatment of myelodysplastic syndromes

Celgene International Sàrl, a subsidiary of Celgene Corporation, today announced that REVLIMID (lenalidomide) has been granted approval by the Swiss agency for Therapeutic Products (Swissmedic) for use in patients with transfusion-dependent anemia due to low-or intermediate-1-risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenic abnormality with or without additional cytogenic abnormalities.

21 Nov 2011

Tufts University professor earns March of Dimes Foundation award for tissue development

A new approach to studying tissue development has earned Catherine K. Kuo, Ph.D., an assistant professor of biomedical engineering in Tufts University's School of Engineering, the Basil O'Connor Starter Scholar Award from the March of Dimes Foundation.

9 Nov 2011