Cell Development News and Research

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Researchers find mechanism that controls the growth of B1-cells

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive - they produce not only antibodies against foreign substances, but also against the body's own substances, and it is unclear why the immune system allows for the development of these particular cells.

13 Nov 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Study explores how the human lung develops at single cell level

The invention of interactive map applications has revolutionized wayfinding, providing an unprecedented level of information far beyond what printed road maps can offer.

18 Oct 2019

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.

8 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

Authenticated mast cells successfully developed from hematopoietic stem cells

Mast cells are critically involved in immunity and immune disorders. However, they are rarely cultured ex vivo for experimental manipulation because of the difficulty in isolating useful numbers and limitations related to 2D culture.

20 Sep 2019

Uncovering new T cell regulatory processes could help treat autoimmune disease

One of the important cells involved in the immune response is the T follicular helper (Tfh) cell. These are important in the normal process of antibody production following immunization, for instance. However, they are also abnormally increased in number in patients with autoimmune disease, such as systemic lupus erythematosus.

16 Sep 2019

'Clock in a dish' provides new way to replicate developmental disorders

In early mammalian development, timing is everything. For healthy development to occur -- whether it be three weeks for a mouse or nine months for a human -- embryos follow the lead of oscillating genes, which turn on and off in precise cycles and trigger different development milestones. Oscillating genes are conductors keeping time in a symphony of growth.

29 Aug 2019

Research reveals potential target for therapies to prevent severe allergic reactions

Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure.

2 Aug 2019

Healthy high-fiber diet could reduce preeclampsia risk

A healthy diet rich in fiber is generally recommended, but new research shows it could be even more important during pregnancy to promote the wellbeing of the mother and child.

10 Jul 2019

Genomic map reveals differences underlying harmful and non-harmful fat

It's not just about how much - the location of where fat is stored in the body can have significant implications for human health.

9 Jul 2019

Zebrafish offers new clues to regenerating damaged cardiac tissue

Research into the hearts of zebrafish, a pet shop staple marked by their eponymous stripes, has shed light on ways the human heart muscle could be healed following damage.

26 Jun 2019

New study could change our understanding of how stem cells differentiate

A pioneering new study led by Florida State University biologists could fundamentally change our understanding of how embryonic stem cells differentiate into specific cell types.

24 Jun 2019

Researchers develop new technology for extracting cell development branching time

One of the greatest achievements of science in recent years is the technology for obtaining information about thousands of individual cells extracted from an organism.

30 May 2019

Johns Hopkins researchers develop method to map retinal cell development

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells.

24 May 2019

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants -- a transfer of blood stem cells from a healthy person to a patient in need.

21 May 2019

Study: All immature cells have potential to develop into stem cells

New sensational study conducted at the University of Copenhagen disproves traditional knowledge of stem cell development.

17 May 2019

Researchers identify gut protein essential for neonatal mice to fight infections

Scientists have identified a protein critical to the immune system development and antibody production in mice, which could contribute to understanding the gut defense mechanism in infants.

8 Apr 2019

Household dust may be contributing to childhood obesity epidemic

New research has found that chemicals found in household dust may promote fat cell development and contribute to increased weight gain in children.

1 Apr 2019

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

Using foreskin tissue from newborn circumcisions, a group of researchers have identified a potential cellular mechanism that connects a mother's smoking while pregnant with an increased risk of offspring obesity later in life.

30 Mar 2019