Cell Nucleus News and Research

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Spatial orgnization of the genome can be altered using small molecules

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs.

16 Apr 2019

High levels of blood lipids may worsen multiple sclerosis symptoms in obese patients

A newly published paper in the Lancet journal EBioMedicine identifies a link between high levels of blood lipids and worsening of disease in multiple sclerosis patients who are overweight or obese.

12 Apr 2019

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

The influence of an active lifestyle on the regenerative capacity of the peripheral nervous system, that is, the set of cranial and spinal nerves that control motor and sensory functions, is described here for the first time, explains Ángel Barco, who has led the participation of the Institute of Neurosciences UMH-CSIC, in Alicante, in this international study.

11 Apr 2019

Scientists solve mystery surrounding common genetic cause of ALS

St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis, or Lou Gehrig's disease.

11 Apr 2019

Bruker highlights innovative NMR capabilities and products at ENC 2019

At ENC 2019, Bruker highlights innovative NMR capabilities and products for biomolecular, materials research and pharmaceutical applications, as well as new scientific software solutions.

From Bruker BioSpin - NMR, EPR and Imaging 10 Apr 2019

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Researchers at Karolinska Institutet present a publicly available resource that can accelerate the use of so-called FISH techniques for studying how the genome is spatially organised in the cell nucleus.

9 Apr 2019

Promising diagnostic, prognostic tools for onset and progression of ALS

Amyotrophic lateral sclerosis is a motor neuron disease with rampant progression and that it is typically fatal within 5 years of prognosis.

5 Apr 2019

Study identifies possible way to predict which melanomas are hot and cold

Melanomas tend to be "hot" or "cold" - if they're hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, and patients with cold tumors tend to show little benefit from immunotherapies.

4 Apr 2019

Salk researchers reveal new role for a driver of metastatic cancers

Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print version of Genes & Development on April 1, 2019.

3 Apr 2019

Designer organelles in living mammalian cells can build synthetic proteins

A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.

30 Mar 2019

UTM researchers uncover 'master pacemaker' for biological clocks

What makes a biological clock tick? According to a new study from U of T Mississauga, the surprising answer lies with a gene typically associated with stem and cancer cells.

28 Mar 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

Prostate cancer cells 'spit out' a protein that promotes tumor growth

Prostate cancer cells change the behavior of other cells around them, including normal cells, by 'spitting out' a protein from their nucleus, new research has found.

26 Mar 2019

High-fat, high-sugar diet in mouse mothers causes problems in the hearts of offspring

A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found that a high-fat, high-sugar diet in mouse mothers before and during pregnancy causes problems in the hearts of their offspring, and that such problems are passed down at least three generations, even if the younger generations only eat a standard mouse chow diet.

22 Mar 2019

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment is known as androgen deprivation therapy.

20 Mar 2019

Cell Nucleus News and Research

Spatial orgnization of the genome can be altered using small molecules

High levels of blood lipids may worsen multiple sclerosis symptoms in obese patients

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

Scientists solve mystery surrounding common genetic cause of ALS

Bruker highlights innovative NMR capabilities and products at ENC 2019

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Promising diagnostic, prognostic tools for onset and progression of ALS

Study identifies possible way to predict which melanomas are hot and cold

Salk researchers reveal new role for a driver of metastatic cancers

Designer organelles in living mammalian cells can build synthetic proteins

UTM researchers uncover 'master pacemaker' for biological clocks

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

Prostate cancer cells 'spit out' a protein that promotes tumor growth

High-fat, high-sugar diet in mouse mothers causes problems in the hearts of offspring

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Piece of puzzle unlocked in what drives alcohol addiction

Scientists identify brain circuit responsible for cocaine-seeking behavior during relapse

Scientists reverse alcohol-seeking behavior in rats with flip of a switch

Blunting emotional component associated with pain

Gene behind mitochondrial disease has more varied effects than previously thought

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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