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Researchers reveal mutation's role in blood cancers

A genetic mutation that disrupts how DNA sends messages to the rest of a cell has been linked to a large number of blood cancers.

3 Feb 2020

Bone marrow chip provides new strategy for understanding Shwachman-Diamond syndrome

A new research tool that mimics the behavior of diseased bone marrow provides a new strategy for understanding the bone marrow disease, Shwachman-Diamond syndrome, and hopefully, developing new treatments.

28 Jan 2020

Scientists develop 3D atlas of bone marrow to help study blood diseases

The bone marrow, which is the spongy and viscous tissue that fills the bone, is the site of blood cell formation or hematopoiesis. If the bone marrow doesn’t work properly, it can lead to many blood diseases, including leukemia, sickle cell anemia, and lymphoma, among others.

23 Dec 2019

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

For the first time, scientists have discovered the molecular mechanism behind how a common virus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell & Host Microbe.

19 Dec 2019

International project to preserve genetic resources of birds

The support is provided by the Russian Foundation for Basic Research and the Science and Innovation in East Asia Consortium. Kazan Federal University's partners are Mahidol University and Kumamoto University.

14 Dec 2019

New research may help guide future treatment for non-alcoholic fatty liver disease

Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch.

11 Dec 2019

Popular cancer drug linked to weight gain and increased systolic blood pressure

National effort to develop implantable bio-artificial kidney achieves key milestone

The Kidney Project, a national effort to develop an implantable bio-artificial kidney that could eliminate the need for dialysis, will announce a key milestone in a November 7, 2019 presentation at the American Society of Nephrology Kidney Week 2019 conference in Washington, DC.

7 Nov 2019

Researchers develop new type of transposase protein with improved biochemical properties

The team, comprising researchers from the European Molecular Biology Laboratory, the Universitätsklinikum Würzburg and the Paul-Ehrlich-Institut, managed to design a new variant of the Sleeping Beauty transposase with dramatically improved biochemical properties.

4 Nov 2019

Nerve cell protection without side effects on erythropoiesis

The hormone erythropoietin (Epo) is a well-known doping substance that has a long history of abuse in endurance sports, such as cycling. In addition to promoting red blood cell production (erythropoiesis), which improves the oxygen supply in the organism, Epo also protects nerve cells from cell death.

25 Oct 2019

UT Southwestern researchers identify novel mechanism that regulates fat formation

In work suggesting new therapeutic targets to fight obesity, UT Southwestern researchers have identified a novel mechanism that regulates the creation of fat in mammals.

18 Sep 2019

FDA approves new drug to treat patients with myelofibrosis

Today, the U.S. Food and Drug Administration approved Inrebic (fedratinib) capsules to treat adult patients with certain types of myelofibrosis.

18 Aug 2019

New strategy may strengthen gut-brain communication

Scientists have developed a strategy that raises the volume of gut-body communication, paving the way for new interventions to improve human health.

28 Jun 2019

New findings may help kick-start aging immune system

The thymus is the powerhouse producing the immune system's T cells, which combat infection in our body.

26 Jun 2019

Researchers define role of rare, influential cells in the bone marrow

Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of the nearly half million blood cells that develop there each day.

23 Apr 2019

Brain can produce new cells even at the age of 90

For the first time, researchers have proven that the brain is capable of producing new nerve cells even at the age of 90 and above.

26 Mar 2019

Study provides new insight into blood cell and immune cell production

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system.

22 Mar 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

Study reveals how a regulatory molecule ensures appropriate supply of blood cells

The body needs to create a continuous supply of blood cells to enter circulation. Blood cells have a wide variety of functions ranging from supplying oxygen to tissues, fighting infections, and enabling the blood to clot upon injury.

13 Mar 2019

Over-abundance of energy to cells could increase cancer risk

It's well-known that obesity, diabetes and chronic inflammation are major risk factors for cancer. But just how cancer evolves in people with these diseases -- and why a healthy diet and exercising regularly can help prevent it -- is poorly understood.

12 Feb 2019