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Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Researchers have been investigating sarbecovirus lineages and the ability of those lineages to evolve the ability to bind ACE2.

7 Feb 2022

Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

New tool harnesses immune cells from tumors to effectively fight cancer

Northwestern scientists have developed a new tool to harness immune cells from tumors to fight cancer rapidly and effectively, published in the journal Nature Biomedical Engineering.

28 Jan 2022

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

In a new study, researchers hypothesized and developed broad-spectrum SARS-CoV-2 inhibitors, ReconnAbs, by modifying the existing non-neutralizing antibodies targeted towards the highly conserved epitopes of the SARS-CoV-2 spike (S) protein combined with a receptor-blocking component.

28 Jan 2022

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Researchers published a study exploring the possibilities of predisposing men for a life-threatening disease course of COVID-19.

24 Jan 2022

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Novel antibody that targets the N-terminal domain of SARS-CoV-2 identified

A new study discusses the targeted discovery of NTD-reactive antibodies from an individual who had recovered from SARS-CoV-2 infection.

19 Jan 2022

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

A major new project will investigate how bacterial defenses influence the spread of segments of DNA called mobile genetic elements (MGEs) between bacteria.

13 Jan 2022

Long-term use of blood pressure medication could be contributing to kidney damage

New kidney research from the University of Virginia School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

12 Jan 2022

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Researchers developed a human A549 lung epithelial cell-based model to probe SARS-CoV-2 replication.

9 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Researchers study influenza and SARS-CoV-2 infection models to identify lung memory B cells during viral infection.

20 Dec 2021

Characterization of the baseline SARS-CoV-2 S-reactive B cell repertoire

Researchers from the University Of Amsterdam have identified several oddities in unvaccinated individuals' antibody response to the spike protein.

8 Dec 2021

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection.

22 Nov 2021

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Researchers isolated single cells among individuals with and without prior infection with the SARS-CoV-2 vaccinated with BNT162b2 mRNA vaccine and compared the nature of the neutralizing antibody response against the original Wuhan virus and the subsequent variants.

25 Oct 2021

Cell Sorting News and Research

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Mutational analysis of SARS-CoV-2 main protease

New tool harnesses immune cells from tumors to effectively fight cancer

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Novel antibody that targets the N-terminal domain of SARS-CoV-2 identified

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

Long-term use of blood pressure medication could be contributing to kidney damage

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Characterization of the baseline SARS-CoV-2 S-reactive B cell repertoire

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Study shows immune profile heterogeneity amongst healthy adults

New research on phagocytosis and SARS-CoV-2's spike protein

A novel FACS-based approach for SARS-CoV-2 serology

Researchers identify key factor responsible for brain development during evolution

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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