Central Nervous System News and Research

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AHRQ: $52.2 billion spent on prescription drugs for treatment of metabolic conditions during 2008

Insurers and consumers spent $52.2 billion on prescription drugs in 2008 for outpatient treatment of metabolic conditions such as diabetes and elevated cholesterol, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

28 Feb 2011

Lyme’s disease and chronic fatigue syndrome biomarkers found

A new study shows that spinal fluid can be used to detect proteins that help distinguish patients with Lyme disease from those with chronic fatigue syndrome.

27 Feb 2011

PACAP hormone levels linked to post-traumatic stress disorder

High blood levels of a hormone produced in response to stress are linked to post-traumatic stress disorder in women but not men, a study from researchers at Emory University and the University of Vermont has found.

25 Feb 2011

Study findings support therapeutic approach for common form of MS

In an effort to develop therapeutic remedies for multiple sclerosis, scientists debate two possible interventional approaches - but they're on opposite sides of the spectrum. Researchers at Wayne State University's School of Medicine, however, have reached a definitive conclusion as to which approach is correct, putting an end to a long-disputed issue.

24 Feb 2011

New research: Spinal fluid proteins can differentiate nPTLS from Chronic Fatigue Syndrome

Patients who suffer from Neurologic Post Treatment Lyme disease and those with the Chronic Fatigue Syndrome report similar symptoms. However unique proteins discovered in spinal fluid can distinguish those two groups from one another and also from people in normal health, according to new research conducted by a team led by Steven E. Schutzer, MD, of the University of Medicine and Dentistry of New Jersey - New Jersey Medical School, and Richard D. Smith, Ph.D., of Pacific Northwest National Laboratory.

24 Feb 2011

ISCTM 7th annual meeting to discuss drug development based on amyloid hypothesis of Alzheimer's disease

Continuing in their mission to promote advances in the development and use of CNS therapeutic agents, the International Society for CNS Clinical Trials and Methodology (ISCTM) met February 21, 2011 in Washington, D.C. to discuss one of the most important issues facing the field today.

23 Feb 2011

Swedish neuroscientist demonstrates how brain produces sense of ownership of the body

Leave your body and shake hands with yourself, gain an extra limb or change into a robot for a while. Swedish neuroscientist Henrik Ehrsson has demonstrated that the brain's image of the body is negotiable. Applications stretch from touch-sensitive prostheses to robotics and virtual worlds.

21 Feb 2011

DiaGenic fourth quarter operating revenue increases to NOK 1,078 thousand

DiaGenic has significantly altered its business strategy during 2010 to leverage more effectively its commercial potential, and strengths in Intellectual Property (IP). The Company has made significant progress in its business activities towards big pharma since implementation of the new strategy. DiaGenic is well positioned as a multimodal partner with large pharma and imaging companies.

18 Feb 2011

Researchers identify normal movement mechanisms of PrPC in brain

Researchers at the University of California, San Diego School of Medicine have identified the motors that move non-infectious prion proteins (PrPC) - found within many mammalian cells - up and down long, neuronal transport pathways.

18 Feb 2011

Vical announces issuance of U.S. Patent for cytomegalovirus vaccines

Vical Incorporated announced today the issuance of U.S. Patent No. 7,888,112 covering DNA vaccines for cytomegalovirus containing specific gene sequences and formulated with Vical's Vaxfectin adjuvant.

16 Feb 2011

PsychoGenics establishes alliance with KineMed to provide specialized neurogenesis services

PsychoGenics today announced the establishment of an alliance with KineMed, to provide specialized neurogenesis services to complement PsychoGenics' in vivo testing capabilities.

15 Feb 2011

Seven-year study demonstrates clear benefits of fetal surgery to treat spina bifida in babies

Results of a landmark, seven-year National Institutes of Health-funded trial, Management of Myelomeningocele Study (MOMS), demonstrate clear benefit for babies who undergo fetal surgery to treat spina bifida, the most common birth defect in the central nervous system.

11 Feb 2011

Human-worm connection research provides insight into brain development, diseases

"Man is but a worm" was the title of a famous caricature of Darwin's ideas in Victorian England. Now, 120 years later, a molecular analysis of mysterious marine creatures unexpectedly reveals our cousins as worms, indeed.

10 Feb 2011

New study: Fetal surgery for spina bifida greatly improves child's mobility

Performing delicate surgery in the womb, months before birth, can substantially improve outcomes for children with a common, disabling birth defect of the spine. Experts at The Children's Hospital of Philadelphia co-led a new landmark study showing that fetal surgery for spina bifida greatly reduces the need to divert fluid from the brain, improves mobility and improves the chances that a child will be able to walk independently.

9 Feb 2011

CeNeRx announces FDA approval of CXB909 IND for neuroprotection and neurodegenerative disorders

CeNeRx BioPharma, Inc., a clinical-stage company developing and commercializing innovative treatments for diseases of the central nervous system (CNS), today announced FDA approval of its IND and reported the first clinical results in humans for CXB909, a novel agent that has demonstrated utility in preclinical models of neuroprotection and neurodegenerative disorders.

9 Feb 2011

Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

A digital signal processing technique long used by statisticians to analyze data is helping Houston scientists understand the roots of memory and learning, Alzheimer's and Parkinson's diseases and stroke.

8 Feb 2011

Transition reports second quarter 2011 net income of $24.28M vs. $6.05M net loss for second quarter 2010

Transition Therapeutics Inc., a product-focused biopharmaceutical company developing therapeutics for disease indications with large markets, today announced its financial results for the quarter ended December 31, 2010.

8 Feb 2011

Targeted delivery combination crosses brain protecting barrier and homes in on tumors

A targeted delivery combination selectively crosses the tight barrier that protects the brain from the bloodstream to home in on and bind to brain tumors, a research team led by scientists from The University of Texas MD Anderson Cancer Center reported in the January issue of the Journal of Clinical Investigation.

2 Feb 2011

Aphios enters subcontract with SAIC-Frederick to develop phospholipid nanoencapsulated camptothecin

Aphios® Corporation today announced that it has entered into a subcontract with SAIC-Frederick, a subsidiary of Science Applications International Corporation, to develop phospholipid nanoencapsulated camptothecin, Camposomes™, for the treatment of pancreatic and other cancers, supporting the NCI Alliance for Nanotechnology.

2 Feb 2011

Research identifies potential reversibility of chronic neurologic disability in stroke survivors

A breakthrough in stroke research identifying the potential reversibility of chronic neurologic disability in stroke survivors has published today. In the February 1, 2011 issue of the journal CNS Drugs the first human results of a new method of targeting chronic brain inflammation years after stroke are reported.

2 Feb 2011

Central Nervous System News and Research

AHRQ: $52.2 billion spent on prescription drugs for treatment of metabolic conditions during 2008

Lyme’s disease and chronic fatigue syndrome biomarkers found

PACAP hormone levels linked to post-traumatic stress disorder

Study findings support therapeutic approach for common form of MS

New research: Spinal fluid proteins can differentiate nPTLS from Chronic Fatigue Syndrome

ISCTM 7th annual meeting to discuss drug development based on amyloid hypothesis of Alzheimer's disease

Swedish neuroscientist demonstrates how brain produces sense of ownership of the body

DiaGenic fourth quarter operating revenue increases to NOK 1,078 thousand

Researchers identify normal movement mechanisms of PrPC in brain

Vical announces issuance of U.S. Patent for cytomegalovirus vaccines

PsychoGenics establishes alliance with KineMed to provide specialized neurogenesis services

Seven-year study demonstrates clear benefits of fetal surgery to treat spina bifida in babies

Human-worm connection research provides insight into brain development, diseases

New study: Fetal surgery for spina bifida greatly improves child's mobility

CeNeRx announces FDA approval of CXB909 IND for neuroprotection and neurodegenerative disorders

Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

Transition reports second quarter 2011 net income of $24.28M vs. $6.05M net loss for second quarter 2010

Targeted delivery combination crosses brain protecting barrier and homes in on tumors

Aphios enters subcontract with SAIC-Frederick to develop phospholipid nanoencapsulated camptothecin

Research identifies potential reversibility of chronic neurologic disability in stroke survivors

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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