Chromosome 18 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 18, one copy inherited from each parent, form one of the pairs. Chromosome 18 spans about 76 million base pairs (the building blocks of DNA) and represents approximately 2.7 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 18 likely contains between 300 and 500 genes.

Genes on chromosome 18 are among the estimated 20,000 to 25,000 total genes in the human genome.
DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

Researchers identify why lymphoma patients may become resistant to specific drug

Researchers identify why lymphoma patients may become resistant to specific drug

New research focuses on noise sensitivity and general fearfulness of canine behavior

New research focuses on noise sensitivity and general fearfulness of canine behavior

Study discovers new genetic risk loci linked to children's food allergies

Study discovers new genetic risk loci linked to children's food allergies

Researchers analyze false-positive results from new prenatal genetic screens

Researchers analyze false-positive results from new prenatal genetic screens

Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

DNA regions that contained telomeres generate RNAs

DNA regions that contained telomeres generate RNAs

Caregivers selected to receive the 2013 Shire BRAVE Awards

Caregivers selected to receive the 2013 Shire BRAVE Awards

DANSR/FORTE assay more effective in diagnosing Edwards and Down syndrome

DANSR/FORTE assay more effective in diagnosing Edwards and Down syndrome

DNA-based prenatal blood test can also identify trisomy 13 and 18

DNA-based prenatal blood test can also identify trisomy 13 and 18

Researchers develop new animal model for studying hemophilia A

Researchers develop new animal model for studying hemophilia A

GWA Study helps scientists identify genetic variant that increases tuberculosis susceptibility in African populations

GWA Study helps scientists identify genetic variant that increases tuberculosis susceptibility in African populations

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

Gene causing progressive form of hair loss identified

Gene causing progressive form of hair loss identified

Microarray analysis can identify chromosome abnormalities in children with Pitt-Hopkins syndrome

Microarray analysis can identify chromosome abnormalities in children with Pitt-Hopkins syndrome

Discovery of common genetic variation associated with colorectal cancer

Discovery of common genetic variation associated with colorectal cancer

Chemical chaperone could open door to treatment of neurological disorder

Chemical chaperone could open door to treatment of neurological disorder

Discovery of new genes associated with fever-related seizures that occur in infancy and childhood

Discovery of new genes associated with fever-related seizures that occur in infancy and childhood

Specific gene found that protects some people with diabetes from severe kidney failure

Specific gene found that protects some people with diabetes from severe kidney failure

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease

Researchers find two locations in the human genome that may harbor genes that increase the risk of Alzheimer’s disease