Chromosome 22 News and Research

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Humans normally have 46 chromosomes (23 pairs) in each cell. Two copies of chromosome 22, one copy inherited from each parent, form one of the pairs. Chromosome 22 is the second smallest human chromosome, spanning about 50 million DNA building blocks (base pairs) and representing between 1.5 percent and 2 percent of the total DNA in cells.

In 1999, researchers working on the Human Genome Project announced they had determined the sequence of base pairs that make up this chromosome. Chromosome 22 was the first human chromosome to be fully sequenced.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 22 likely contains between 500 and 800 genes.

Genes on chromosome 22 are among the estimated 20,000 to 25,000 total genes in the human genome.
Brain coupling patterns as predictive markers for psychosis in 22q11.2DS

Brain coupling patterns as predictive markers for psychosis in 22q11.2DS

Research offers new insight into the causes of spina bifida

Research offers new insight into the causes of spina bifida

New biomarkers identified for predicting psychosis risk in 22q11.2 deletion syndrome

New biomarkers identified for predicting psychosis risk in 22q11.2 deletion syndrome

VTC professor awarded NIH grant to study a potential therapy for DiGeorge syndrome

VTC professor awarded NIH grant to study a potential therapy for DiGeorge syndrome

Age-induced methylation changes in the sperm epigenome contribute to offspring's medical problems

Age-induced methylation changes in the sperm epigenome contribute to offspring's medical problems

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

Brain activity patterns during sleep shed light on the neurobiology behind 22q11.2 Deletion Syndrome

Artificial intelligence tool to predict the risk of psychotic illness

Artificial intelligence tool to predict the risk of psychotic illness

Research offers new hope for people affected by the microdeletion of chromosome 22

Research offers new hope for people affected by the microdeletion of chromosome 22

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

People born with a heart defect have low risk of moderate or severe COVID-19 infection

People born with a heart defect have low risk of moderate or severe COVID-19 infection

Misfiring brain cells may create swallowing difficulties in children with neurodevelopmental disorders

Misfiring brain cells may create swallowing difficulties in children with neurodevelopmental disorders

Scientists unravel mechanisms that lead to ventricular enlargement in schizophrenia

Scientists unravel mechanisms that lead to ventricular enlargement in schizophrenia

New study provides clear picture of brain abnormalities associated with schizophrenia

New study provides clear picture of brain abnormalities associated with schizophrenia

Study seeks participants with VCFS-related psychosis to help create biobank of cerebral organoids

Study seeks participants with VCFS-related psychosis to help create biobank of cerebral organoids

Researchers investigate how to prevent the onset of schizophrenia using mouse model

Researchers investigate how to prevent the onset of schizophrenia using mouse model

Researchers map uncharted area of genome using advanced imaging

Researchers map uncharted area of genome using advanced imaging

Research opens up new avenues for understanding the causes of schizophrenia

Research opens up new avenues for understanding the causes of schizophrenia

Children's Tumor Foundation establishes significant research initiative to combat NF2

Children's Tumor Foundation establishes significant research initiative to combat NF2

Study: Under-connectivity is the underlying cause of brain disorders

Study: Under-connectivity is the underlying cause of brain disorders

Zebrafish offers clue to alleviate gastrointestinal distress related to autism

Zebrafish offers clue to alleviate gastrointestinal distress related to autism

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