Chromosome 4 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.
Research offers new insight into how to treat endometriosis

Research offers new insight into how to treat endometriosis

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

Study provides insight into fitness effects of genomic structural variants in natural populations

Study provides insight into fitness effects of genomic structural variants in natural populations

Structure of BRCA2 protein complex critical for DNA repair solved

Structure of BRCA2 protein complex critical for DNA repair solved

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

SMC protein complex plays a decisive role in the dynamics of holocentromeres

SMC protein complex plays a decisive role in the dynamics of holocentromeres

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

Study offers genetic insights into the underlying biology of reproductive aging

Study offers genetic insights into the underlying biology of reproductive aging

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

In-depth sequencing of SARS-CoV-2 variants crucial in controlling outbreaks

In-depth sequencing of SARS-CoV-2 variants crucial in controlling outbreaks

Scientists uncover genetics involved in COVID-19 induced respiratory failure

Scientists uncover genetics involved in COVID-19 induced respiratory failure

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

Transient chromosomal errors can spur the formation of tumors, study finds

Transient chromosomal errors can spur the formation of tumors, study finds

Researchers discover new genetic driver of autism and other developmental disorders

Researchers discover new genetic driver of autism and other developmental disorders

Optical genome mapping could change the existing workflow within cytogenetic laboratories

Optical genome mapping could change the existing workflow within cytogenetic laboratories

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Study unravels the link between chromosomal instability and cellular senescence

Study unravels the link between chromosomal instability and cellular senescence

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