Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 6, one copy inherited from each parent, form one of the pairs. Chromosome 6 spans about 171 million base pairs (the building blocks of DNA) and represents between 5.5 percent and 6 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 1,100 and 1,600 genes.
Genes on chromosome 6 are among the estimated 20,000 to 25,000 total genes in the human genome.
With genomic sequencing at The Wellcome Trust Sanger Institute and other centres, researchers now have an extensive catalogue of the 30,000 or so genes that contain the instructions to make a human or a mouse.
In a region of DNA long considered a genetic wasteland, Harvard Medical School researchers have discovered a new class of gene.
A healthy person’s genome contains 46 chromosomes, but an individual cell can contain less. Contemporary methods allow to determine the value of losses rather accurately. The Tomsk researchers’ effort has been supported by the Russian Foundation for Basic Research.
Dr. Fraser discusses, for the first time, the significance of the discovery of anthrax toxin genes in a naturally occurring microbe other than Bacillus anthracis, the bacterium that causes anthrax.
Despite a roller-coaster ride of ups and downs during the past 15 years, gene therapy has continued to attract many of the world's brightest scientists. They are tantalized by the enormous potential that replacing missing genes or disabling defective ones offers for curing diseases of many kinds.
An Oxford-led team of researchers has found out more about what happens during recombination, the process by which the genetic information you inherited from your mother and father is mixed up to make a sex chromosome to pass on to your offspring.
Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that abnormally short telomeres - the end-caps on chromosomes that normally preserve genetic integrity -appear to play a role in the early development of many types of cancer.
Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals. The discovery was made by applying the latest laboratory methods to a strain of mice restored from embryos frozen since the early 70s.
By comparing the genomes of an alga, a weed and humans, a team of researchers has identified a new gene behind Bardet-Biedl syndrome (BBS), a complex condition marked by learning disabilities, vision loss and obesity.
Recently completed genetic analysis reveals that half of the more than 300 inherited canine disorders — including a number of cancers — resemble specific diseases of man; many scientists believe that the dog genome holds a wealth of information that will benefit human health.
An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children. The finding is expected to lead to a genetic test, enabling rapid and definitive diagnosis of the syndrome, as well as prenatal testing for families who already have one child with the disease.
A new version of the human male is a distinct possibility, given the genetic erosion of the “junk” sex-determining chromosome that makes men male.
A new international study of children with a severe form of acute lymphoblastic leukemia(ALL) shows that certain chromosome losses can signal an especially poor response to therapy, but that other chromosome abnormalities have no effect on treatment survival.
Researchers at The University of Texas M. D. Anderson Cancer Center are describing an entirely new way by which cells can become cancerous. And they say their finding provides an answer to a mystery in lung and other cancers.
Finding provides an answer to a mystery in lung and other cancers: why a potent tumor suppressor gene called FUS1 functions as it should, yet none of the protein it produces can be found anywhere in a cancer cell.
A new international study of children with a severe form of acute lymphoblastic leukemia (ALL) shows that certain chromosome losses can signal an especially poor response to therapy, but that other chromosome abnormalities have no effect on treatment survival.
Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.
By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease.
A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.
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