Citalopram News and Research

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Citalopram is an antidepressant drug used to treat major depression associated with mood disorders. It is also used on occasion in the treatment of body dysmorphic disorder and anxiety.

Antidepressant just as effective as antipsychotic in treating dementia

Research in Canada has revealed that when it comes to treating the aggressive behaviour seen in people with Alzheimer's disease, antidepressants work just as well as a commonly prescribed antipsychotic medication but without the severe side-effects.

11 Sep 2007

Antidepressant citalopram shows promise in treating symptoms of dementia

Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia.

11 Sep 2007

Gene variation makes people with depression more likely to respond to the medication citalopram

A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, has found.

3 Aug 2007

Use of SSRIs during pregnancy does not increase the risk for most birth defects

Use of certain antidepressants, selective serotonin-reuptake inhibitors most commonly known as SSRIs, during pregnancy does not significantly increase the risk for most birth defects, according to a new Centers for Disease Control and Prevention (CDC) study, released in the New England Journal of Medicine (NEJM).

27 Jun 2007

Genetic variations may help explain why some men with depression develop suicidal thoughts

Although most patients with depression respond favorably to antidepressant medications, a very small subgroup may experience worse symptoms after beginning treatment, according to background information in the article.

5 Jun 2007

Potential for first diagnostic DNA test to guide antidepressant treatment

Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one -- or right combination -- is, at times, a matter of trial and error.

31 Oct 2006

Depression treatment may require different drugs for different people

If a first antidepressant medication doesn't work, try a different one, UT Southwestern Medical Center researchers report.

27 Mar 2006

Link between genetic variation and outcome of antidepressant treatment

Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at the National Institutes of Health (NIH) has discovered.

15 Mar 2006

Second-generation Antidepressants

A recent article in the prestigious British Medical Journal seems to confirm an increased risk for suicidal behavior among adults taking popular antidepressants. This follows evidence that certain selective serotonin reuptake inhibitors (SSRIs) may have a similar effect among children and adolescents.

27 Feb 2005

Newborns may be harmed when pregnant women take Selective Serotonin Re-uptake Inhibitors (SSRIs) and other anti-depressants during the third trimester of pregnancy

Health Canada is advising Canadians that newborns may be adversely affected when pregnant women take Selective Serotonin Re-uptake Inhibitors (SSRIs) and other newer anti-depressants during the third trimester of pregnancy.

9 Aug 2004

New Drug Application for a novel dosage format of citalopram for the treatment of depression

Biovail Corporation has announced that the Food and Drug Administration (FDA) has accepted for review (effective date June 13, 2004) Biovail's submission of a New Drug Application (NDA) for a novel dosage format of citalopram for the treatment of depression.

14 Jun 2004

Canadians advised of stronger warnings for selective serotonin re-uptake inhibitors and other newer anti-depressants

Health Canada is advising Canadians that Selective Serotonin Re-uptake Inhibitors (SSRIs) and other newer anti-depressants, now carry stronger warnings. These new warnings indicate that patients of all ages taking these drugs may experience behavioural and/or emotional changes that may put them at increased risk of self-harm or harm to others.

11 Jun 2004

Adrenaline packs a powerful punch in the use of antidepressants

Researchers from the University of Pennsylvania School of Medicine found that norepinephrine (adrenaline) plays an important role in animals in determining behavioral effects in some of the most commonly prescribed antidepressants, regardless of which biochemical pathway the drug uses to alleviate symptoms of depression.

3 Jun 2004

New and Generic Drug Approvals from FDA

This newly approved or tentatively approved drug listing from the FDA is an interim page intended to provide timely information on new drug products as a more comprehensive page is developed.

12 Apr 2004