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Targeted combinatorial drug treatment restores beta cell function in mice

The loss of the identity of insulin-secreting beta cells in the islet of Langerhans, a process also called beta cell dedifferentiation, has been proposed to be a main reason for the development of diabetes.

20 Feb 2020

MD Anderson collaborates with Denali Therapeutics to advance novel therapies for neurodegenerative diseases

The University of Texas MD Anderson Cancer Center today announced a strategic research collaboration with Denali Therapeutics Inc. to develop novel therapies for Alzheimer's and other neurodegenerative diseases.

20 Feb 2020

The challenge of new antibiotic discovery

It is important to discover antibiotic drugs and to bring them to clinical use, a task made all the more urgent by the increase in the number of infections that are resistant to existing antibiotics. However, this task is a formidable one.

28 Jan 2020

Study could lead to next-generation clinical testing for hidden hearing loss

A pair of biomarkers of brain function -- one that represents "listening effort," and another that measures ability to process rapid changes in frequencies -- may help to explain why a person with normal hearing may struggle to follow conversations in noisy environments, according to a new study led by Massachusetts Eye and Ear researchers.

28 Jan 2020

Expert genomics panel disputes certain genes linked to a dangerous heart condition

A panel of experts have said that nine genes linked to a dangerous heart disorder called long QT syndrome, are not associated with the condition.

27 Jan 2020

Meridian launches High-Specificity Pfu HS Mix to increase customers’ testing capabilities

Meridian Bioscience, Inc. today announced the launch of a High-Specificity Pfu HS Mix that not only provides high-fidelity amplification, but also offers market-leading amplification for companion diagnostic (CDx) and clinical testing.

From Meridian Bioscience, Inc. 24 Jan 2020

Specific group of immune cells may influence Alzheimer’s disease

A new study has revealed that the immune system plays a crucial and previously unidentified role in Alzheimer's disease.

9 Jan 2020

Post-mortem genetic testing used to find underlying cause of sudden deaths in Amish families

Researchers used post-mortem genetic testing to find the underlying cause of multiple sudden deaths in young people and sudden cardiac arrests in two large Amish families.

8 Jan 2020

Dana-Farber Cancer Institute to create Chen-Huang Center for EGFR Mutant Lung Cancers

Dana-Farber Cancer Institute will create the Chen-Huang Center for EGFR (epidermal growth factor receptor) Mutant Lung Cancers to stimulate research, promote clinical trials, and strengthen the Institute's capabilities for studying and treating lung cancer.

7 Jan 2020

Researchers show new potential path to improve bone-repair procedures

Researchers are moving closer to a new approach for improving spinal fusion procedures and repairing broken or defective bones that avoids an over-production of bone that commonly occurs in current treatments.

3 Jan 2020

A reality check on artificial intelligence: Are health care claims overblown?

Health products powered by artificial intelligence, or AI, are streaming into our lives, from virtual doctor apps to wearable sensors and drugstore chatbots.

30 Dec 2019

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Radiotherapy can effectively reduce or even eliminate some tumors; others, however, show enduring resistance. Considering the potentially harmful side effects of radiotherapy, clinicians agree that it is paramount to be able to determine if a patient will benefit from radiotherapy before exposing them to any of the associated risks.

17 Dec 2019

Study shows nilotinib drug is safe and well tolerated in patients with Parkinson's disease

A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson's disease finds that it is reasonably safe and well tolerated.

17 Dec 2019

New strategy could prevent side effects of targeted cancer treatment

Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor, a protein that stimulates cell proliferation.

13 Dec 2019

'Fuzzy logic' alarm system may help nurses in NICU predict impending catheter infusion failure

A "fuzzy logic" alarm system may help nurses in the neonatal intensive care unit predict impending catheter infusion failure – and prevent complications in critically ill newborns, reports a study in the October issue of Advances in Neonatal Care, official journal of the National Association of Neonatal Nurses.

11 Dec 2019

UMSOM researchers to test the safety, tolerability of prototype Shigella-ETEC vaccine

Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli, and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.

10 Dec 2019

Hybrid antibiotics show promising results in eradicating deadly staph infections

Eradicating deadly staph using a new breed of antibiotics has revealed promising results in research released by QUT, to help overcome one of the biggest modern medical challenges.

4 Dec 2019

Researchers identify a promising drug pair to attack deadly childhood brain cancers

Researchers have devised a new plan of attack against a group of deadly childhood brain cancers collectively called diffuse midline gliomas, including diffuse intrinsic pontine glioma, thalamic glioma and spinal cord glioma.

20 Nov 2019

'Fuzzy logic' alarm system may help NICU nurses predict catheter infusion failure

A "fuzzy logic" alarm system may help nurses in the neonatal intensive care unit (NICU) predict impending catheter infusion failure – and prevent complications in critically ill newborns, reports a study in the October issue of Advances in Neonatal Care, official journal of the National Association of Neonatal Nurses.