Codeine News and Research

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Opioid withdrawal in Ontario newborns increases 15-fold

The number of newborns suffering from opioid withdrawal increased 15-fold in Ontario over 20 years, according to research published today in CMAJ Open.

12 Feb 2015

Morphine after tonsillectomy may be life threatening for children

Treating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, new research has found.

27 Jan 2015

Childbearing women who take painkillers may face increased risk of birth defects

More than one-fourth of privately-insured and one-third of Medicaid-enrolled women of childbearing age filled prescriptions for opioid-based (narcotic) painkillers between 2008 and 2012, according to a new analysis published today by the U.S. Centers for Disease Control and Prevention in its Morbidity and Mortality Weekly Report (MMWR).

23 Jan 2015

AHS provides updated assessment of treatments for acute migraine

The January issue of the American Headache Society journal Headache provides an updated assessment of the best treatments to use when a migraine attack occurs. The assessment will form the basis of new AHS treatment guidelines.

21 Jan 2015

European countries implement ATOME project to study improved access to essential painkillers

Governments in 12 European countries are to implement the recommendations of research into why more patients are not receiving essential painkillers.

15 Jan 2015

Researchers find that one in six Ontario adults reports a history of TBI

Nearly seventeen per cent of adults surveyed in Ontario said they have suffered a traumatic brain injury that left them unconscious for five minutes or required them to be hospitalized overnight, according to new research. These same adults also reported more substance use, smoking and recent psychiatric distress.

11 Dec 2014

Opioid tramadol can increase hospitalization risk for hypoglycemia

The opioid pain-reliever tramadol appears to be associated with an increased risk of hospitalization for hypoglycemia, a potentially fatal condition caused by low blood sugar, according to a report published online by JAMA Internal Medicine.

9 Dec 2014

Three IU researchers receive $2.1 million to develop computational biology models of liver toxicity

Three Indiana University professors have received $2.1 million to develop a computational model of acetaminophen-induced liver failure -- the leading cause of liver failure in the United States -- by using advanced microscopic and computational technologies that allow scientists to see into the liver of a living animal.

5 Dec 2014

Excess consumption of common pain relievers poses significant health risks to Australians

On the final day of Be Medicinewise Week 2014, NPS MedicineWise is reminding people that excess consumption of common pain relievers is a serious medicine safety issue.

20 Oct 2014

AAN releases new position statement on opioids for chronic non-cancer pain

According to a new position statement from the American Academy of Neurology, the risk of death, overdose, addiction or serious side effects with prescription opioids outweigh the benefits in chronic, non-cancer conditions such as headache, fibromyalgia and chronic low back pain.

30 Sep 2014

Teva Canada recalls Biomedic Acetaminophen with Codeine owing to missing child-resistant packaging

Teva Canada Limited, in consultation with Health Canada, is recalling one lot (#669745) of Biomedic Acetaminophen with Codeine (30 caplets with 300 mg acetaminophen and 8 mg codeine) due to missing child-resistant packaging.

30 Sep 2014

Study of chronic users of CCS finds deficits in specific regions of brain white matter

An imaging study of chronic users of codeine-containing cough syrups (CCS) has found deficits in specific regions of brain white matter and associates these changes with increased impulsivity in CCS users.

21 Aug 2014

People born in Canada are at highest risk of overdose or death from codeine than Immigrants

Immigrants are at lower risk of an overdose or death after being prescribed codeine than people born in Canada, a new study has found.

13 Aug 2014

Study on cancer care offers model for possible lower spending on treatment

The study, however, raised some questions because while it cut costs by a third and showed no decline in patient health, the spending on chemotherapy medications rose.

9 Jul 2014

Prescription drug deaths drop in Fla. after crackdown on doctors

Deaths involving narcotic painkillers dropped 26 percent over two years in Florida after stricter doctor scrutiny, according to a report from the federal Centers for Disease Control and Prevention.

2 Jul 2014

Backpack-sized device can perform highly accurate and sensitive cocaine testing in 15 minutes

Testing for cocaine and other drugs usually involves two steps: a quick on-site prescreen, and then a more accurate confirmatory test at a distant laboratory.

26 Jun 2014

Braeburn announces new clinical trial for Probuphine based on clear guidance from FDA

Braeburn Pharmaceuticals announced today the initiation of a new clinical trial for Probuphine® based on clear guidance from the U.S. Food and Drug Administration (FDA). The study, which was submitted for FDA review in mid-March, is expected to begin enrollment by mid-year and to be completed by the middle of 2015.

30 Apr 2014