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New guideline supports use of acetaminophen and NSAIDs for pediatric dental pain

Acetaminophen or non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are recommended as first-line treatments for managing short-term dental pain in children under age 12, according to a new clinical practice guideline developed by the American Dental Association Science & Research Institute (ADASRI), the University of Pittsburgh School of Dental Medicine and the Center for Integrative Global Oral Health at the University of Pennsylvania School of Dental Medicine.

25 Aug 2023

New biologic inactivates potent opioid and reverses overdose

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose.

18 Apr 2023

Study finds lack of high certainty evidence on the efficacy and safety of analgesics for low back pain

Despite nearly 60 years of research, there is still a lack of high certainty evidence on the effectiveness and safety of commonly used painkillers (analgesics) for short bouts of low back pain, finds an analysis of the evidence published by The BMJ.

23 Mar 2023

Maternal opioid treatment after delivery not associated with adverse infant outcomes

Infants born to mothers prescribed opioids after delivery, mostly after a cesarean, are at no greater risk of harm shortly after birth than infants of mothers not prescribed opioids, finds a large study from Canada published by The BMJ today.

16 Mar 2023

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Researchers demonstrated the presence of infectious SARS-CoV-2 in samples from the hospital rooms of SARS-CoV-2-infected patients.

21 Nov 2022

New long-term opioid use associated with a heightened risk of death, study finds

New long term use of opioids to quell pain after lung cancer surgery is linked to a 40% heightened risk of death from any cause within the next 2 years, finds research published online in the journal Regional Anesthesia & Pain Medicine.

13 Sep 2022

Kratom: A dangerous or beneficial plant?

A new study summarizes the traditional and modern uses of kratom, as well as its pharmacology, benefits, and adverse health impacts.

23 Jun 2022

Study shows a small increased risk of congenital abnormalities in infants exposed to opioids in utero

A new study in CMAJ shows a small increased risk of congenital abnormalities in infants exposed to opioid medications in the first trimester of pregnancy.

7 Feb 2022

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

About 12 percent of patients who receive implantable cardiac devices such as a pacemaker or defibrillator and fill an opioid prescription after surgery will consistently use the pain medication in the months afterward, raising the potential for addiction following these common procedures and identifying another pathway that could contribute to the national opioid crisis, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

26 Nov 2021

Children and young adults are frequently exposed to unsafe opioid prescriptions, study suggests

Children and young adults who have pain from surgery, dental care and other conditions are often prescribed opioids.

19 Aug 2021

Opioids like ‘lean’ permeate hip-hop culture, but dangers are downplayed

Nykerrius Williams knows about the close relationship between hip-hop and opioid use. Williams, 27, an independent rapper from Gibsland, Louisiana, who goes by the name Young Nyke, took oxycodone pills for the first time when he was 16 and has continued patterns of misuse of those pills, as well as Lortabs, Xanax and codeine cough syrups, until recently. To him, it's part of the business.

28 May 2021

Novel non-opioid approach to relieve pain after knee surgery

A new study by Henry Ford Health System published in Arthroscopy: The Journal of Arthroscopic and Related Surgery may signal a first step toward eliminating the use of opioids to relieve pain after knee surgery.

26 Apr 2021

Despite new CDC guidance, opioid prescription rates have not declined

Research from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a schedule II opioid for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC).

2 Dec 2020

First-time opioid prescriptions may lead to substance-related problems later in life

Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers.

11 Aug 2020

Opioid initiation risk in young adults, adolescents may not be as high as previously thought

10 Aug 2020

Study: Nearly 10% of patients continue to use opioids more than 90 days after heart surgery

Nearly 10 percent of patients who are prescribed opioid medications following heart surgery will continue to use opioids more than 90 days after the procedure, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

17 Jun 2020

Fentanyl tops the list of drugs detected in overdose patients at Baltimore hospitals

A new University of Maryland study found fentanyl tops the list of drugs detected in overdose patients at two Baltimore hospital emergency departments.

12 Jun 2020

Opioid prescription for chronic non-cancer pain increased in the last two-and-a-half decades

The number of people with chronic non-cancer pain prescribed an opioid medicine worldwide increased in the last two-and-a-half decades.

25 Feb 2020

Family doctors in rural America tackle crisis of addiction and pain

Dr. Angela Gatzke-Plamann didn’t fully grasp her community’s opioid crisis until one desperate patient called on a Friday afternoon in 2016.

10 Jan 2020

Addictions and drug interactions common among patients not disclosing their medication history

Some patients skip telling their doctors about the drugs and medications they are consuming. A new study shows that these patients are at a greater risk of unpleasant and sometimes dangerous drug-drug interactions as well as addictions. The study was published in the latest issue of The Journal of the American Osteopathic Association. The study is titled, “Role of opioid-involved drug interactions in chronic pain management”.

11 Dec 2019