Colorectal News and Research

RSS

Researchers identify small-molecule inhibitors that effectively target FAK enzyme in colon cancer

Researchers have identified two small-molecule inhibitors that effectively targeted the focal adhesion kinase (FAK), an enzyme present in certain cancers that helps tumors thrive and survive.

29 Oct 2010

Researchers develop three-dimensional culture that mimics growth patterns of colon cancer stem cells

University of Pittsburgh researchers have devised a three-dimensional system in laboratory culture that mimics the growth patterns of colon cancer stem cells in patients. Their findings were presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

New noninvasive stool DNA test to predict colorectal cancer

An investigational DNA methylation test could alter the screening landscape for colorectal cancer, according to data presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held here Oct. 27-30, 2010.

29 Oct 2010

Researchers find link between telomere length and colorectal cancer risk

For the first time, researchers have found a link between long telomeres and an increased risk for colorectal cancer, according to research presented at the American Association for Cancer Research special conference on Colorectal Cancer Biology to Therapy, held here Oct. 27-30, 2010.

29 Oct 2010

Government institutions need to find alternate funding sources for colorectal cancer screening

Offering colorectal cancer screening to poor minority women during mammography visits can effectively expand screening in this otherwise underserved population, although lack of medical insurance remains a significant barrier. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The results highlight the need to find alternative funding sources for colorectal cancer screening from the government or private institutions.

28 Oct 2010

Pfizer announces publication of crizotinib data for NSCLC patients in New England Journal of Medicine

Pfizer Inc. announced today the publication of data showing that 57 percent of ALK-positive advanced non-small cell lung cancer (NSCLC) patients treated with crizotinib (PF-02341066), an investigational oral anaplastic lymphoma kinase (ALK) inhibitor, had either a complete (one patient) or partial (46 patients) response to treatment. Data from 82 patients in this Part 2 expansion cohort of the Phase 1 study were published in the October 28 issue of the New England Journal of Medicine.

28 Oct 2010

Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Laureate Pharma, Inc., a full-service contract development and manufacturing organization, announced today that they have entered into a development and manufacturing agreement to produce AV-203, AVEO Pharmaceutical's (Cambridge, MA) novel monoclonal antibody targeted against ErbB3.

28 Oct 2010

Epigenomics presents data on Septin9 biomarker clinical study for colorectal cancer at UEGW

Epigenomics AG, the cancer diagnostics company, announced that new data obtained in a clinical study with the Company's proprietary Septin9 biomarker for the blood-based detection of colorectal cancer, were presented yesterday at the 18th United European Gastroenterology Week (UEGW) in Barcelona, Spain.

28 Oct 2010

Five ways to prevent bowel cancer: Study

According to the latest research five simple lifestyle changes could cut the risk of bowel cancer by 23%. The Danish study enrolled 57,053 adults aged 50 to 64 without cancer between 1993 and 1997. They were followed up closely for 10 years. Results showed that people who followed public health recommendations (not smoking, a healthier diet, etc.) for each of these areas had a lower risk of developing colorectal cancer during this time.

27 Oct 2010

New G-DOC repository for biological information

Georgetown Lombardi Comprehensive Cancer Center, part of Georgetown University Medical Center, announces the launch of the Georgetown Database of Cancer or G-DOC. Under development for two years, G-DOC is a repository for biological information that is normally only available in scattered information libraries and tissue banks, if at all. Data sets grow as researchers deposit new information. G-DOC also contains relevant tools to analyze the data, plus new ones not seen before.

27 Oct 2010

Adherence to lifestyle recommendations reduces risk of colorectal cancer by 23%

Almost a quarter of colorectal (bowel) cancer cases could be prevented if people followed healthy lifestyle advice in five areas including diet and exercise, says a new study published on bmj.com today.

27 Oct 2010

Study finds association between KRAS p.G13D mutations and cetuximab treatment in colorectal cancer

Even though the cancer-treatment agent cetuximab is not considered effective treatment for KRAS (a gene)-mutated metastatic colorectal tumors, new research indicates that patients with colorectal cancer not responding to chemotherapy and a certain variation of this gene who were treated with cetuximab had longer overall and progression-free survival than patients with other KRAS-mutations, according to a study in the October 27 issue of JAMA.

27 Oct 2010

Oncolytics presents REO 013 clinical trial data for colorectal cancer at International Symposium in Spain

Oncolytics Biotech Inc. announced today that interim data from a U.K. translational clinical trial (REO 013) investigating intravenous administration of REOLYSIN in patients with metastatic colorectal cancer prior to surgical resection of liver metastases was presented at the International Symposium on Cytotoxic T-lymphocytes (CTL) and Immunostimulation being held in Pamplona, Spain.

27 Oct 2010

Amgen reports $3,816 million for 2010 third quarter revenue

Amgen reported revenue unchanged for the third quarter of 2010 at $3,816 million versus $3,812 million for the third quarter of 2009.

26 Oct 2010

New report highlights numerous monoclonal antibodies for treating digestive system cancers

Since the early development of monoclonal antibodies (mAbs), almost forty years ago, twenty-four therapeutic mAbs have been approved, four of them targeting digestive system cancers. Due to this success (two blockbusters reaching sales of over $1 billion), many industrials position themselves on this very attractive sector.

25 Oct 2010

Research Roundup: U.S. life expectancy ratings; Medicare Advantage outlook; Should advanced cancer patients have routine screening tests?

Health Affairs: What Changes In Survival Rates Tell Us About US Health Care -- Proponents of changes in the U.S. health system have often pointed to studies that find health outcomes in this country are worse than other developed nations, even though the United States "spends well over twice the median expenditure of industrialized nations on health care, and far more than any other country as a percentage of its gross domestic product." Others point to high rates of smoking, obesity and traffic fatalities.

25 Oct 2010

Experts identify efficient way to increase minority access to colorectal cancer screening

Minority patients have a significantly decreased survival from colon cancer compared to white patients, most often as a result of a late diagnosis. To help address this problem, a team of healthcare professionals at Memorial Sloan-Kettering Cancer Center has identified an efficient way to increase minority access to lifesaving colorectal cancer screening (CRCS) in communities where multiple barriers to preventive care exist.

25 Oct 2010

AACR to host special conference on colorectal cancer

The American Association for Cancer Research will hosts its first special conference on Colorectal Cancer: Biology to Therapy from Oct. 27-30, 2010, at the Loews Hotel, Philadelphia.

22 Oct 2010

ACOG joins Jay Monahan Center to develop new chapter on Female Cancers resource guide

The New York State Chapter of the American Congress of Obstetricians and Gynecologists, District II (ACOG) has partnered with the Jay Monahan Center for Gastrointestinal Health at NewYork-Presbyterian Hospital/Weill Cornell Medical Center to develop the fifth and final chapter to the Focus on Female Cancers resource guide.

22 Oct 2010

National Staging Initiative to standardize cancer stage information across Canada

Canadians can expect to benefit from more targeted investments in cancer screening and treatment as a result of a first-of-its-kind initiative that is standardizing the collection of cancer stage information across Canada. The initiative marks a change that cancer experts have wanted for more than 20 years, and that will help cancer system decision-makers to target areas of greatest need in cancer control.

21 Oct 2010

Colorectal News and Research

Researchers identify small-molecule inhibitors that effectively target FAK enzyme in colon cancer

Researchers develop three-dimensional culture that mimics growth patterns of colon cancer stem cells

New noninvasive stool DNA test to predict colorectal cancer

Researchers find link between telomere length and colorectal cancer risk

Government institutions need to find alternate funding sources for colorectal cancer screening

Pfizer announces publication of crizotinib data for NSCLC patients in New England Journal of Medicine

Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Epigenomics presents data on Septin9 biomarker clinical study for colorectal cancer at UEGW

Five ways to prevent bowel cancer: Study

New G-DOC repository for biological information

Adherence to lifestyle recommendations reduces risk of colorectal cancer by 23%

Study finds association between KRAS p.G13D mutations and cetuximab treatment in colorectal cancer

Oncolytics presents REO 013 clinical trial data for colorectal cancer at International Symposium in Spain

Amgen reports $3,816 million for 2010 third quarter revenue

New report highlights numerous monoclonal antibodies for treating digestive system cancers

Research Roundup: U.S. life expectancy ratings; Medicare Advantage outlook; Should advanced cancer patients have routine screening tests?

Experts identify efficient way to increase minority access to colorectal cancer screening

AACR to host special conference on colorectal cancer

ACOG joins Jay Monahan Center to develop new chapter on Female Cancers resource guide

National Staging Initiative to standardize cancer stage information across Canada

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News