Conjugation News and Research

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Beckman Coulter offers largest range of single color CE-IVD and ASR conjugated antibodies

Beckman Coulter Life Sciences now offers its largest portfolio of single color CE-IVD and ASR (analyte-specific reagent) conjugated antibodies.

From Beckman Coulter Life Sciences - Flow Cytometry 30 Jul 2018

SYGNIS AG extends manufacturing capability for Lightning-Link technology

SYGNIS AG, the Group which includes Expedeon Holdings, Expedeon, and C.B.S. Scientific Company, today announced it has extended the manufacturing capability for its Lightning-Link technology, currently marketed under the Expedeon brand, to support scalability and bulk production of antibodies.

16 Apr 2018

SYGNIS AG launches new Universal Lateral Flow Assay kit and files patent application

SYGNIS AG today announced the launch of its Universal Lateral Flow Assay kit, the latest addition to its expanding range of lateral flow assay products and services which are being commercialized under the Expedeon brand name.

16 Apr 2018

Chemist finds how to control blood sugar without usual side effects

Chemist Robert Doyle in the College of Arts and Sciences at Syracuse University has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.

11 Feb 2018

New modular platform offers robust biological approach that targets endless number of diseases

The biological complexity of cancer and other diseases demands a more formidable arsenal of therapies than currently available. Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease-related genes.

1 Feb 2018

Reducing use of antibiotics not sufficient to reverse drug resistance

Researchers have discovered that reducing the use of antibiotics will not be enough to reverse the growing prevalence of antibiotic resistance for some types of bacteria.

22 Nov 2017

Hibernating ground squirrels offer clues to fight against stroke-induced brain damage

In the fight against brain damage caused by stroke, researchers have turned to an unlikely source of inspiration: hibernating ground squirrels.

17 Nov 2017

Rare transition metal can simplify design and preparation of antibody therapies

Rice University scientists have developed a method to efficiently modify natural antibodies that can deliver drugs to target cells. Adding a little extra metal is the key.

24 Aug 2017

Study identifies key component that allows deadly bacteria to spread antibiotic resistance

Antibiotic resistance of the bacterium Staphylococcus aureus is responsible for 11,300 deaths a year in the United States alone -- a figure that corresponds to half of all deaths caused by gram-positive resistant bacteria in that country.

26 Jul 2017

TSRI scientists receive $3.3 million NIH grant to create new breast cancer treatments

A pair of scientists from the Florida campus of The Scripps Research Institute have been awarded up to $3.3 million from the National Cancer Institute of the National Institutes of Health to create the next generation of breast cancer treatments for the thousands of patients whose current treatment options are limited.

14 Feb 2017

Review shows how nanocarriers can solve problems with drug delivery in ocular tissues

Most ophthalmic diseases are usually treated with topically administered drug formulations (e.g. eye drops).

3 Jan 2017

Scientists develop biocompatible, highly stretchable optical fibers for long-term diagnostics

Researchers from MIT and Harvard Medical School have developed a biocompatible and highly stretchable optical fiber made from hydrogel -- an elastic, rubbery material composed mostly of water.

17 Oct 2016

BBI Solutions introduces novel conjugate blocking technology to improve performance of lateral flow immunoassays

BBI Solutions has launched Morffi, a novel conjugate blocking technology that enhances signal intensity and improves the sensitivity of lateral flow immunoassays, at the Lateral Flow Test Development seminar in Seattle, USA, on the 20th September.

21 Sep 2016

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic biguanide, also inhibits respiration, but proguanil, which is widely used for the prevention of malaria, does not.

12 Aug 2016

Moffitt researchers discover novel way to control SETDB1 protein upregulated in cancer

Cancer is a group of more than 100 different diseases. All are driven by cells and genes that escape the normal process of division and begin their own plan to replicate in the body.

8 Jul 2016

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

A protein modified to increase the amount of time it circulates in the bloodstream appears to reverse liver fibrosis and cirrhosis in rats, according to results of a study led by Johns Hopkins researchers.

3 Mar 2016

Block copolymer hydrogels facilitate cryoprotection of red blood cells and increase tissue engineering

Freezing of medical tissue and cells usually requires the addition of cryopreservatives, although the added compounds can have undesired effects in subsequent applications.

2 Feb 2016

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

For about the last 25 years, the cardiology group here have been developing a platform technology for both the diagnosis and treatment of atherosclerosis.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 28 Oct 2015

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications.

18 Aug 2015

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Immunotherapy using monoclonal antibodies is a promising treatment strategy, and it might now be within reach: American scientists have successfully prepared an oligosaccharide enterobacterial antigen for which a monoclonal antibody has been developed. The study is published in the journal Angewandte Chemie.

31 Jul 2015