Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.
Vascular endothelial cells (VECs) form the walls of blood vessels and play a critical role in inflammation.
A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants.
Dana-Farber researchers found that rituximab reduced the severity of chronic graft-versus-host disease (GVHD) in 70 percent of the study participants.
The U.S. Food and Drug Administration (FDA) has given approval for the use of the asthma drug Flovent HFA in children four to eleven years of age.
...perhaps explaining why current therapies sometimes fail, report researchers from Children's Hospital Boston in the New England Journal of Medicine.
Chemotherapy for a disorder of the immune system may - at least in theory - be effective against severe human avian influenza infection, this suggest scientists at the Karolinska Institutet.
A new Mayo Clinic study reveals the most common causes of allergic contact dermatitis, a skin inflammation resulting in swollen, reddened and itchy skin due to direct contact with an allergen.
Psoriasis, a chronic skin condition characterized by thick, red, scaly patches that itch and bleed, not only makes the activities of daily life difficult, but also can affect a person's emotional well being.
Researchers at Georgetown University Medical Center say they now have a clearer picture of how an extract from the leaves of the Ginkgo biloba tree reduces the risk of aggressive cancer in animal experiments.
An inflammatory disease of the immune system, rheumatoid arthritis (RA) is associated with increased occurrence of lymphoma--or cancers of the lymphatic system, which plays an integral role in the body's ability to fight infection.
Intensive care unit physicians can increase the success of mechanical ventilation weaning and shorten the weaning period by identifying critically ill patients who have adrenal insufficiency and treating them with the hormone hydrocortisone (cortisol).
Aston Academy of Life Sciences, the clinical research hospital of Aston University, has recently been commissioned to assess the efficacy and safety of a specialist drug, Posurdex (Allergan Ltd, UK), which is used in the treatment of patients who suffer from a sight threatening condition, called macular oedema.
In a small study from a referral center for dermatology, most patients receiving prolonged oral corticosteroids for chronic skin diseases were not receiving therapies to prevent osteoporosis that may be caused by the drug, according to an article in the January issue of Archives of Dermatology.
While both inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRA) have been proven to help control mild-to-moderate persistent asthma in school-age children, a new study shows ICS may be the more effective treatment.
People suffering from exercise-induced asthma were able to reduce their symptoms below the threshold used to diagnose the disease by eating a diet supplemented with fish oil, according to new research findings from Indiana University reported in the January issue of the journal Chest.
Since smoking became popular in America in the 1930s, lung cancer rates have continued to climb. Today, it is still the leading cause of cancer-related deaths, with totals more than the other five leading cancers combined.
The reviews appear in the current issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.
A combination of airway-opening drugs and inhaled inflammation-reducing steroids works better at preventing severe asthma attacks than a normal dose of steroids alone, according to a new review of recent studies.
Corticosteroids are used often in the treatment of infectious mononucleosis, and for reasons beyond usual criteria, according to a study in the October issue of Archives of Otolaryngology–Head & Neck Surgery.
Researchers at the University of California, San Diego (UCSD) School of Medicine have announced successful completion of Phase II clinical trials of a novel drug for the treatment of rheumatoid arthritis (RA), one that works without suppressing the patient's immune system.