Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

New clinical standards on the treatment of patients with cystic fibrosis

New clinical standards on the treatment of patients with cystic fibrosis (CF) have been released following an exhaustive review of all available literature.

16 Nov 2007

Hope on the horizon for hereditary angioedema sufferers

Although there is currently no treatment approved by the Federal Drug Administration (FDA) for acute attacks of hereditary angioedema (HAE) - a genetic disease causing swelling of extremities, face and internal organs that can be life-threatening - hope is on the horizon according to a team of experts presenting the latest research at the Annual Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Dallas.

14 Nov 2007

Managing asthma

The great majority of the nearly 23 million people with asthma, including 6.5 million children, can avoid serious symptoms and disability if they follow the latest guidelines to keep their disease under control.

13 Nov 2007

Prazosin curbs brain damage from post-traumatic stress disorder

A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.

6 Nov 2007

Medical College of Wisconsin receives grant to study infantile hemangiomas

The Food and Drug Administration (FDA) has awarded the Medical College of Wisconsin in Milwaukee a three-year, $1 million Orphan Products Development grant to study infantile hemangiomas – a vascular tumor of the skin or internal organs.

25 Oct 2007

Infliximab scheduled treatment has proven to be an effective strategy in IBD patients

Crohn's disease (CD) and ulcerative colitis (UC) are chronic-relapsing diseases, the clinical courses of which are characterized by periods of remission and periods of acute flare up, determining clinical symptoms which have a strong impact on the quality of life for patients.

25 Oct 2007

Funding source a major determinant in findings regarding adverse effects in corticosteroid studies

Studies of inhaled corticosteroids, medications frequently prescribed for asthma and other respiratory problems, appear less likely to find adverse effects if they are funded by pharmaceutical companies than if they are funded by other sources, according to a report in the October 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

22 Oct 2007

Study looks at sepsis and purpura in children

While survival rates for sepsis have increased over the past two decades, children under four and those in adolescence remain highly susceptible to the condition.

18 Oct 2007

Study looks at inhaled corticosteroid use post 9/11 in NYC firefighters

Inhaled corticosteroids (ICS), anti-inflammatory treatments often prescribed for asthma, may be beneficial in preventing respiratory illness, according to a new study.

18 Oct 2007

Children with neuromuscular diseases at risk for decreased bone density

Children with neuromuscular diseases such as muscular dystrophy, may be at risk for suboptimal bone density due to low levels of vitamin D.

18 Oct 2007

Relief for arthritic knees

If you're among the estimated 10 million Americans who have been diagnosed with osteoarthritis of the knee, take heart in knowing that several nonsurgical options, pharmacologic and otherwise, are available for easing the pain of an arthritic knee, according to Cleveland Clinic's Arthritis Advisor.

25 Sep 2007

Repeat steroids to premature infants linked to cerebral palsy

Repeated courses of a drug that is used to improve the survival of unborn premature babies also may increase the risk of cerebral palsy in those children, according to results from a multi-center study, funded by the National Institutes of Health and led by Ronald Wapner, M.D., professor of obstetrics and gynecology, Columbia University Medical Center and attending obstetrician and gynecologist at NewYork-Presbyterian Hospital/Columbia.

21 Sep 2007

Repeat courses of corticosteroids in mothers linked to increased rate of cerebral palsy among children

When pregnant women are at high risk for preterm birth, giving them a single injection of corticosteroids has been shown to reduce the baby's chances of having serious lung problems after birth.

21 Sep 2007

Repeat steroids to premature infants linked to cerebral palsy

20 Sep 2007

New guidelines for childhood asthma recommend inhaled corticosteroids

New guidelines aimed at dealing with asthma have been released by government health experts in the United States.

30 Aug 2007

GSK supports emphasis on asthma control in treatment guidelines

New asthma treatment guidelines issued today urge healthcare professionals to first assess the severity of a patient's asthma to determine and administer initial treatment and then obtain regular assessments of the patient's level of asthma control.

29 Aug 2007

Higher rates of new asthma among WTC workers

Findings released by the Health Department shed new light on the health effects of exposure to dust and debris among workers who responded to the World Trade Center disaster on September 11, 2001.

28 Aug 2007

GSK receives FDA 'not approvable letter' for Advair for COPD

GlaxoSmithKline has announced that the U.S. Food and Drug Administration (FDA) has issued a not approvable letter for the supplemental drug application for the 500/50 strength of Advair Diskus (fluticasone propionate and salmeterol inhalation powder) in the treatment of patients with chronic obstructive pulmonary disease (COPD).

9 Aug 2007

Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

Dexamethasone steroid treatment shows no benefit for kids with bronchiolitis

DMC Children's Hospital of Michigan has found that a common steroid treatment often prescribed for kids with bronchiolitis has no impact on improving their symptoms or in reducing hospitalization.

26 Jul 2007