Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Right medications essential for allergy control

Choosing the right medications is essential to gaining control over symptoms as allergy season comes into full bloom, allergy specialists at UT Southwestern Medical Center warn.

10 May 2007

Daily steroid treatments help boys with muscular dystrophy walk longer

Boys with Duchenne muscular dystrophy were able to walk on their own for a longer period of time and reduce their risk of scoliosis as a result of receiving daily steroid treatments for several years, according to a study published in the May 8, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

8 May 2007

FDA advisory committee supports Advair 500/50 in reducing COPD exacerbations

An Advisory Committee to the Food and Drug Administration (FDA) has unanimously agreed that GlaxoSmithKline's Advair Diskus 500/50 (fluticasone propionate and salmeterol inhalation powder) demonstrated a significant reduction in the risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the U.S.

2 May 2007

1.2 million hospitalized patients experienced an adverse drug event

In 2004, 1.2 million hospitalized patients experienced an adverse drug event, 90 percent of which were due to a side effect from a medication that was properly administered, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

25 Apr 2007

New method predicts hip joint decay from chemotherapy

Investigators at St. Jude Children's Research Hospital say they have found the best way for predicting when patients will need future surgery to repair hip joints that have deteriorated because of pediatric leukemia or lymphoma treatment.

20 Apr 2007

Local corticosteroid injection for carpal tunnel syndrom

A single corticosteroid injection in the wrist can offer at least a month of relief to people suffering from severe carpal tunnel syndrome, according to an updated review of studies by Canadian researchers.

20 Apr 2007

Steroids for acute sinusitis

Every year, nearly 37 million Americans suffer from the sinus pressure, nasal congestion, cough and postnasal drip that accompany sinusitis.

19 Apr 2007

Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults

A new review suggests that asthma treatment based on tests of fluid coughed up from the lungs could reduce the frequency and severity of flare-ups in adult asthma patients.

19 Apr 2007

Aspirin, cancer and lung inflamation

Two new studies by researchers at the at the Mayo Clinic have found that taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) on a regular basis may offer some protection against cancer.

18 Apr 2007

Studies highlight role of inflammation in cancer

Can reducing inflammation keep cancer at bay? Two novel studies presented at the 2007 Annual Meeting of the American Association for Cancer Research that examine use of common anti-inflammatory agents suggest this might be the case.

18 Apr 2007

Gleevec available to patients in post-surgical GIST study

Investigators will begin offering Gleevec(R) (imatinib mesylate)* tablets to patients receiving placebo in a major North American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following surgery were significantly less likely to experience a return of their cancer compared to those not taking this innovative therapy.

15 Apr 2007

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

GlaxoSmithKline has announced the initiation of a global, open-label, single group trial that will assess the efficacy, safety and tolerability of PROMACTA (eltrombopag olamine) in patients previously treated for chronic idiopathic thrombocytopenic purpura (ITP).

15 Apr 2007

Corticosteroids after cardiac surgery lower risk of atrial fibrillation

Patients who receive corticosteroids after cardiac surgery have a significantly lower risk of atrial fibrillation in the days following the surgery, according to a study in the April 11 issue of JAMA.

11 Apr 2007

Inhaled corticosteroids deserve further consideration for lung cancer chemoprevention

Among a group of mostly older male veterans suffering from chronic obstructive pulmonary disease (COPD), an illness that offers a greater susceptibility to lung cancer, researchers found that regular use of high dose inhaled corticosteroids (ICS) lowered the risk of developing lung cancer.

4 Apr 2007

FDA wants warning label on omalizumab (Xolair)

The Food and Drug Administration (FDA) announced that it has requested Genentech, Inc. add a boxed warning to the product label for omalizumab, marketed as Xolair.

21 Feb 2007

Chemotherapy drug bortezomib packs a one-two punch

Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors.

20 Feb 2007

Time, therapy spur recovery from sudden sensorineural hearing loss

A first-of-its-kind study into time-dependent treatments of sudden sensorineural hearing loss published in the February 2007 issue of Otolaryngology- Head and Neck Surgery has determined that a combination of time and oral corticosteroid therapy can play a key role in helping patients regain full hearing, often within a month of the initial loss of hearing.

29 Jan 2007