Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

It's a vicious circle - exposure to stress causes anxiety and depression

Experts in the United States say the results of a study with mice suggests that stress in itself may cause anxiety and depression.

18 Apr 2006

Locally injected steroids may not do much good for chronic headache pain

Locally injected steroids apparently don't enhance treatments for acute headache or migraine pain.

18 Apr 2006

Anxiogenic-like effect of chronic corticosterone in the light-dark emergence task in mice

Neuroscientists at Harvard Medical School and its affiliate McLean Hospital have shown that long-term exposure to stress hormone in mice directly results in the anxiety that often comes with depression.

18 Apr 2006

Targeting the inflamed synovium: The quest for specificity

In the April 2006 issue of Arthritis & Rheumatism, noted rheumatology specialists with Kings College London, Dr. Toby Garrood and Dr. Costantino Pitzalis offer an overview of recent breakthroughs and a preview of future directions in this critical quest for specificity.

4 Apr 2006

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Vascular endothelial cells (VECs) form the walls of blood vessels and play a critical role in inflammation.

4 Apr 2006

Novel therapy for chronic graft-versus-host disease

A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants.

28 Mar 2006

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Dana-Farber researchers found that rituximab reduced the severity of chronic graft-versus-host disease (GVHD) in 70 percent of the study participants.

27 Mar 2006

Asthma drug approved for children age four up

The U.S. Food and Drug Administration (FDA) has given approval for the use of the asthma drug Flovent HFA in children four to eleven years of age.

26 Mar 2006

A newly recognized type of immune cell may play an important role in causing asthma

...perhaps explaining why current therapies sometimes fail, report researchers from Children's Hospital Boston in the New England Journal of Medicine.

21 Mar 2006

Swedish theory suggests treatment for Avian Influenza Infection

Chemotherapy for a disorder of the immune system may - at least in theory - be effective against severe human avian influenza infection, this suggest scientists at the Karolinska Institutet.

8 Mar 2006

Study reveals most common causes of allergic contact dermatitis

A new Mayo Clinic study reveals the most common causes of allergic contact dermatitis, a skin inflammation resulting in swollen, reddened and itchy skin due to direct contact with an allergen.

7 Mar 2006

Topical therapies show promise for Psoriasis

Psoriasis, a chronic skin condition characterized by thick, red, scaly patches that itch and bleed, not only makes the activities of daily life difficult, but also can affect a person's emotional well being.

6 Mar 2006

Ginkgo biloba reduces aggressive cancer risk in animal experiments

Researchers at Georgetown University Medical Center say they now have a clearer picture of how an extract from the leaves of the Ginkgo biloba tree reduces the risk of aggressive cancer in animal experiments.

27 Feb 2006

Study associates chronic, severe inflammation with increased lymphoma risk among RA patients

An inflammatory disease of the immune system, rheumatoid arthritis (RA) is associated with increased occurrence of lymphoma--or cancers of the lymphatic system, which plays an integral role in the body's ability to fight infection.

27 Feb 2006

Hormone hydrocortisone (cortisol) supplementation improves ventilator weaning

Intensive care unit physicians can increase the success of mechanical ventilation weaning and shorten the weaning period by identifying critically ill patients who have adrenal insufficiency and treating them with the hormone hydrocortisone (cortisol).

2 Feb 2006

Aston Academy investigates macular oedema

Aston Academy of Life Sciences, the clinical research hospital of Aston University, has recently been commissioned to assess the efficacy and safety of a specialist drug, Posurdex (Allergan Ltd, UK), which is used in the treatment of patients who suffer from a sight threatening condition, called macular oedema.

26 Jan 2006

Bisphosphonate use in dermatology patients receiving long-term oral corticosteroid therapy

In a small study from a referral center for dermatology, most patients receiving prolonged oral corticosteroids for chronic skin diseases were not receiving therapies to prevent osteoporosis that may be caused by the drug, according to an article in the January issue of Archives of Dermatology.

16 Jan 2006

Inhaled corticosteroids most effective for persistent asthma in children

While both inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRA) have been proven to help control mild-to-moderate persistent asthma in school-age children, a new study shows ICS may be the more effective treatment.

11 Jan 2006

Fish oil shown to reduce airway inflammation caused by exercise-induced asthma

People suffering from exercise-induced asthma were able to reduce their symptoms below the threshold used to diagnose the disease by eating a diet supplemented with fish oil, according to new research findings from Indiana University reported in the January issue of the journal Chest.

10 Jan 2006

Vaccine that targets nicotine rather than the brain's reaction to it

Since smoking became popular in America in the 1930s, lung cancer rates have continued to climb. Today, it is still the leading cause of cancer-related deaths, with totals more than the other five leading cancers combined.

3 Nov 2005