Craniofacial News and Research

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Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

Researchers unravel how gingival mesenchymal stem cells accelerate wound healing

Ever notice how a cut inside the mouth heals much faster than a cut to the skin? Gum tissue repairs itself roughly twice as fast as skin and with reduced scar formation. One reason might be because of the characteristics of gingival mesenchymal stem cells, or GMSCs, which can give rise to a variety of cell types.

15 Mar 2018

Researchers developing rapid saliva test to detect Zika virus

Researchers at New York University College of Dentistry, in collaboration with Rheonix, Inc., are developing a novel test for Zika virus that uses saliva to identify diagnostic markers of the virus in a fraction of the time of current commercial tests.

24 Feb 2018

Modifications in HIV test enable rapid detection of Zika virus, study states

A new comprehensive study details a novel test for Zika virus, which utilizes saliva for rapid identification of the diagnostic markers of the virus.

23 Feb 2018

Elevated oral pathogens, less bacterial diversity linked to risk of developing precancerous gastric lesions

Elevated pathogen colonization and a lack of bacterial diversity in the mouth were identified in people with precancerous lesions that could precede stomach cancer, finds a new study led by New York University College of Dentistry and New York University School of Medicine.

28 Nov 2017

ASU professor reveals more about craniofacial conditions before release of ‘Wonder’

The new film "Wonder" tells the story of a young boy who overcomes the challenges of living with the facial structural abnormality known as Treacher Collins Syndrome.

17 Nov 2017

Fever in first trimester of pregnancy increases risk for birth defects, study shows

Fevers in a mother's first trimester of pregnancy increase the baby's risk for some heart defects and facial deformities such as cleft lip or palate, but exactly how this happens is unclear. Scientists have debated whether a virus or other infection causes the defects, or if fever alone is the problem.

12 Oct 2017

Duke researchers unravel how fever in early pregnancy increases risk for heart, facial birth defects

Researchers have known for decades that fevers in the first trimester of pregnancy increase risk for some heart defects and facial deformities such as cleft lip or palate. Exactly how this happens is unclear. Scientists have debated whether a virus or other infection source causes the defects, or if fever alone is the underlying problem.

10 Oct 2017

NYU Dentistry awarded grant to test impact of simple treatment on cavity progression

The National Institute of Dental & Craniofacial Research, part of the National Institutes of Health, has awarded a grant that will provide funding to New York University College of Dentistry and its collaborators to test the effectiveness of silver diamine fluoride in stopping the progression of cavities in young children.

10 Oct 2017

Forsyth researchers win $5.4 million NIH award to pursue research on oral microbes

A research team led by the Forsyth Institute today received a $5.4 million award from the National Institutes of Health to pursue revolutionary research of microbes living in the mouth and within the human body.

6 Oct 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

New method can offer cost-effective solution to assess OSA risk and severity

Obstructive sleep apnea syndrome (OSA) affects approximately 34% of men and 17% of women within the adult population. Although sex, aging, and obesity are the main factors associated with OSA, research has shown that larger tongue, lateral pharyngeal walls, tonsils, soft palate, and total pharyngeal soft tissue volumes can also be considered OSA risks. Prior research has largely relied on calipers, which are used to measure the oral cavity and craniofacial dimensions of subjects, but there are limited data on reproducibility, and the process is generally considered cumbersome and unpleasant.

12 Sep 2017

CSHLP releases new book on Tissue Engineering and Regenerative Medicine

Cold Spring Harbor Laboratory Press announced the release of Tissue Engineering and Regenerative Medicine, available on its website in hardcover, paperback, and ebook formats.

6 Sep 2017

Rutgers University leadership creates great strides in breakthrough scientific research

Less than a decade ago, the U.S. Department of Defense established the Armed Forces Institute of Regenerative Medicine I with a multimillion dollar grant to focus research centered on regenerative medicine for the treatment of battlefield injuries and selected Rutgers University-New Brunswick to lead the civilian research program.

26 Aug 2017

Digital technology could help reliably diagnose cleft lips and palates in remote patients

In today’s connected world, surgeons and anesthesiologists have the ability to use widely available technology, such as GoPro cameras, Skype, WebEx, and Google Chat to remotely care for patients in distant countries.

23 Aug 2017

Study offers new, quicker way to test for Zika virus

For the first time, researchers are using proteomics to examine proteins and peptides in saliva in order to accurately detect exposure to Zika virus.

21 Aug 2017

Researcher receives NIH grant to study genetic mutation that prevents tooth formation

Inherited genetic mutations can rob up to 7 percent of the population of their smile. Several genes are important for the placement and patterning of teeth.

9 Aug 2017

NYU researcher to study biological differences between men and women in oral cancer pain

Nicole Scheff, PhD, a postdoctoral fellow in the laboratory of Dr. Brian L. Schmidt, director of the NYU Bluestone Center for Clinical Research and the NYU Oral Cancer Center, both located at New York University College of Dentistry, has received a two-year, $120,000-plus F32 grant from the National Institute of Dental and Craniofacial Research.

10 Jul 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

Calcium carbonate, or CaCO3, comprises more than 4% of the earth's crust. Its most common natural forms are chalk, limestone, and marble, produced by the sedimentation of the shells of small fossilized snails, shellfish, and coral over millions of years.

8 Jun 2017