Creatine News and Research

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Creatine is an endogenous amino acid which is synthesized from simpler amino acids, namely glycine, arginine and the sulfur-containing amino acid methionine. Approximately 95 percent of creatine in the body is stored in skeletal muscle.

Increasing energy supply within injured spinal cord nerves could help them heal

When the spinal cord is injured, the damaged nerve fibers--called axons--are normally incapable of regrowth, leading to permanent loss of function.

3 Mar 2020

PerkinElmer provides newborn screening assay for PPMD’s New York State pilot program

PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today announced that it is providing the newborn screening assay for Parent Project Muscular Dystrophy’s Newborn Screening Pilot for Duchenne Muscular Dystrophy (Duchenne).

From Revvity 14 Jan 2020

Machine learning algorithm predicts life expectancy in heart failure patients

When Avi Yagil, PhD, Distinguished Professor of Physics at University of California San Diego flew home from Europe in 2012, he thought he had caught a cold from his travels. When a "collection of pills" did not improve his symptoms, his wife encouraged him to see a doctor.

13 Nov 2019

GlobalData: New unpronounceable ingredients are leaving consumers confused

Gone are the days where whey powder was considered an exotic ingredient. Recently consumers have been exposed to a multitude of ingredients options leading to ingredients overload where consumers can’t keep up in a time where they are looking for simplicity and real ingredients in their purchase decisions.

11 Nov 2019

Molecular gatekeepers that regulate calcium ions vital for muscle health and repair

Calcium ions are essential to how muscles work effectively, playing a starring role in how and when muscles contract, tap energy stores to keep working and self-repair damage.

31 Oct 2019

Creatine powers fight against cancer, improves efficacy of immunotherapies

The immune system functions as the body’s defense against pathogens and harmful substances, including cancer cells. They protect the body against potential harm. In cases of cancer, though the body tries to fight the tumor cells, they may become too aggressive for the immune system to eradicate.

21 Oct 2019

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according to new UCLA research.

18 Oct 2019

Managing fluid volume and salt losses during a marathon may help avoid post-race kidney injury

Legend states that after the Greek army defeated the invading Persian forces near the city of Marathon in 490 B.C.E., the courier Pheidippides ran to Athens to report the victory and then immediately dropped dead.

30 Aug 2019

Liver dysfunction provokes cerebral molecular disturbances in two weeks

The liver plays a vital role as a filter in the human body. But what happens when it malfunctions? Researchers from the Universities of Geneva and Lausanne, the Vaud University Hospital Centre, the Centre for Biomedical Imaging, the Federal Polytechnic School of Lausanne and the University Hospitals of Geneva, Switzerland, teamed up to perform a detailed analysis of hepatic encephalopathy, a type of brain damage caused by chronic liver disease.

19 Aug 2019

Extremely strenuous exercise can overload the heart without increasing cardiac risk

Researchers have found no evidence of elevated cardiac risk in runners who completed a 24-hour ultramarathon (24UM), despite the transient elevation of blood biomarkers that measure cardiac health.

28 Jun 2019

Researchers measure brain metabolite levels in people with mild memory problems

Using strong and targeted but noninvasive magnets at specific sites in the brains of people with and without mild learning and memory problems, Johns Hopkins researchers report they were able to detect differences in the concentrations of brain chemicals that transmit messages between neurons.

20 Mar 2019

Statins associated with low risk of side effects

The cholesterol-lowering drugs called statins have demonstrated substantial benefits in reducing the risk of heart attacks and strokes caused by blood clots (ischemic strokes) in at-risk patients.

10 Dec 2018

Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

Takeda Pharmaceutical Company Limited today announced that intracranial efficacy data from the Phase 3 ALTA-1L (ALK in Lung Cancer Trial of BrigAtinib in 1st Line) trial showed improved intracranial progression-free survival (PFS) and intracranial objective response rate (ORR) with ALUNBRIG (brigatinib) compared to crizotinib among anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC) patients.

22 Oct 2018

Lumos acquires license for LUM-201 drug that promotes secretion of growth hormone

Lumos Pharma, Inc., a clinical stage biopharmaceutical company focused on development and commercialization of therapeutics for rare and neglected diseases, today announced that it has acquired the license for LUM-201, an investigational orally administered small molecule that promotes secretion of growth hormone from the pituitary gland, from Ammonett Pharma LLC.

24 Sep 2018

CHMP adopts positive opinion of Takeda’s ALUNBRIG for treatment of ALK+ non-small cell lung cancer

Takeda Pharmaceutical Company Limited today announced that the European Medicines Agency's Committee for Medicinal Products for Human Use has adopted a positive opinion, recommending the full approval of ALUNBRIG® as a monotherapy for the treatment of adult patients with anaplastic lymphoma kinase-positive advanced non-small cell lung cancer previously treated with crizotinib.

24 Sep 2018

Researchers discover potential new approach to block growth of HER2 positive breast cancer

Researchers at Mayo Clinic have identified an important new pathway by which HER2 positive breast cancers grow and have discovered that a dietary supplement called cyclocreatine may block the growth of HER2 positive breast cancer.

30 Aug 2018

Drinking alcohol alters adolescents’ metabolism and grey matter volume

A study conducted in eastern Finland has shown that moderate-to-heavy drinking among young adults is associated with changes in their metabolic profile.

29 Jun 2018

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with moderately to severely active ulcerative colitis. Xeljanz is the first oral medication approved for chronic use in this indication.

30 May 2018

Many patients show CKD signs prior to diabetes diagnosis

Many patients who will later be diagnosed with diabetes show signs of chronic kidney disease (CKD) even before their diabetes diagnosis, according to a study by researchers with the University of Tennessee Health Science Center and VA MidSouth Healthcare Network.

14 Mar 2018

CHOP researchers explore effective nutritional therapies for mitochondrial disease

Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems.

10 Jan 2018