Crohn’s Disease News and Research

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Serological biomarker predicts severe Crohn's disease seven years prior to diagnosis

An international team led by a University of Toronto researcher has found that an antibody detectable in blood predicts severe Crohn's disease and is detectable up to seven years prior to disease diagnosis.

24 May 2022

Children who grow up with dogs may have protection from Crohn's disease later in life

Young children who grow up with a dog or in a large family may have some protection later in life from a common inflammatory bowel disease known as Crohn's disease, according to a study to be presented at Digestive Disease Week 2022.

23 May 2022

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

Researchers described two studies, the CLOFIT retrospective study and the COTEST real-time study, that investigated if maintaining adequate immune fitness could significantly add to the current strategies of preparedness for COVID-19 and other pandemics.

28 Apr 2022

Intestinal inflammation liberates chemicals that nourish the growth of E. coli in Crohn's disease

A multi-year study of the role of E. coli gut bacteria in Crohn's disease finds that intestinal inflammation liberates chemicals that nourish the bacteria's growth and promotes their ability to cause inflammation.

27 Apr 2022

Association between the COVID-19 pandemic and inflammatory bowel disease presentation in New York City

Researchers evaluated the association between new IBD diagnoses in NYC and the COVID-19 pandemic.

29 Mar 2022

Exploring the vital connection between gut microbes, physical activity, and health

Our bowels accommodate billions of active microbes that affect the health, a fact that is arousing increasing interest also among athletes.

26 Mar 2022

Intensive treatment for patients with Crohn's disease found to be safe

Intensive treatment for patients with Crohn's disease showed no safety differences compared to the current standard of care, according to a trial published in the journal Gastroenterology.

1 Mar 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Research lays the groundwork to better understand and treat Crohn's disease

A paper published this week in Immunity, a leading research journal highlighting discoveries in immunology by Cell Press, lays the groundwork to better understand and treat Crohn's disease, a type of Inflammatory Bowel Disease (IBD).

9 Feb 2022

Research may lead to new treatment options for Crohn's disease patients

Results of a new study by researchers at Case Western Reserve University represent a step toward improving our understanding of Crohn's disease and the factors that cause its intestinal inflammation.

10 Jan 2022

Weak T-cell clonal response to SARS-CoV-2 vaccination in IBD patients deficient in antibody-responders

Researchers investigate the post-vaccination clonal T-cell response and its relationship to antibody responses in IBD patients.

15 Dec 2021

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Pregnant patients with mild to moderate COVID-19 were treated with MAb and reported no adverse effects.

30 Nov 2021

Study identifies possible link between psychological stress and Crohn's disease flare-ups

A possible link between psychological stress and Crohn's disease flare-ups has been identified by a McMaster University-led study.

18 Nov 2021

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

A recent study evaluates the immune responses elicited by COVID-19 vaccines in infliximab- or vedolizumab-treated IBD patients.

15 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Study identifies serotonin as a possible trigger of flare-ups in Crohn's disease

A new treatment may be on the horizon for people with a major form of inflammatory bowel disease (IBD) called Crohn's disease, after a McMaster University-led study identified serotonin as a possible trigger of flare-ups.

6 Nov 2021

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Many diseases have their origin in early human development, and today (8th September), two publications in Nature reveal how researchers from the Human Cell Atlas (HCA) consortium are advancing understanding of this.

9 Sep 2021

Increasing your risk of IBD through processed food

In this interview, News-Medical speaks to Dr. Neeraj Narula about ultra-processed food and how this can increase your risk of developing inflammatory bowel disease(IBD).

27 Jul 2021

Ultra-processed foods increase the risk of inflammatory bowel disease

Ultra-processed foods containing high levels of added sugar, fat, and salt, but lacking in vitamins and fiber, are key contributors to the development of IBD.

16 Jul 2021

Fungi that live in the gut may be equally important in health and disease

Bacteria's role in gut health has received a lot of attention in recent years. But new research led by scientists at University of Utah Health shows that fungi-;another microorganism that lives within us-;may be equally important in health and disease.

14 Jul 2021