Cyclophosphamide News and Research

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Cyclophosphamide is a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It is also used to treat some types of kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent. Also called CTX and Cytoxan.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
Study on B-cell depletion therapy

Study on B-cell depletion therapy

Herceptin does not increase heart failure in patients long-term

Herceptin does not increase heart failure in patients long-term

Benefits of Herceptin are lasting

Benefits of Herceptin are lasting

Methods for treating lupus nephritis

Methods for treating lupus nephritis

Oncolytic viruses deliver a knockout punch to cancers

Oncolytic viruses deliver a knockout punch to cancers

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

Researchers discover how cyclophosphamide chemotherapy drug helps a cancer-killing virus

Researchers discover how cyclophosphamide chemotherapy drug helps a cancer-killing virus

Biomira Stimuvax prostate cancer study results published

Biomira Stimuvax prostate cancer study results published

Circulating bone-marrow derived cells do not contribute to egg formation

Circulating bone-marrow derived cells do not contribute to egg formation

Benefit of chemotherapy in breast cancer depends on estrogen status of tumors

Benefit of chemotherapy in breast cancer depends on estrogen status of tumors

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Botox finds a use in cancer treatment

Botox finds a use in cancer treatment

Mycophenolate mofetil helps treat lupus patients

Mycophenolate mofetil helps treat lupus patients

New drug CellCept far more effective in treating kidney problems in lupus patients

New drug CellCept far more effective in treating kidney problems in lupus patients

New treatment advances for patients with follicular lymphoma

New treatment advances for patients with follicular lymphoma

Medulloblastoma irradiation may impair reading skills in young children

Medulloblastoma irradiation may impair reading skills in young children

Testing for the activity of certain genes can predict response to chemotherapy for breast cancer

Testing for the activity of certain genes can predict response to chemotherapy for breast cancer

Rituximab provides new hope for people with lupus

Rituximab provides new hope for people with lupus

Chemo combo increases breast cancer survival

Chemo combo increases breast cancer survival

Emergence of cancer as a major cause of death among children in developing regions of the world is not being adequately addressed

Emergence of cancer as a major cause of death among children in developing regions of the world is not being adequately addressed