Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Researchers develop new way to prevent diseases caused by herpesvirus infections

Researchers develop new way to prevent diseases caused by herpesvirus infections

Researchers develop new way to test strength of immune response

Researchers develop new way to test strength of immune response

Study provides potential new target to combat cytomegalovirus infections

Study provides potential new target to combat cytomegalovirus infections

First case-control study examines link between microcephaly and in utero Zika virus infection

First case-control study examines link between microcephaly and in utero Zika virus infection

Malformations in the brains of fetuses caused by Zika virus go beyond microcephaly

Malformations in the brains of fetuses caused by Zika virus go beyond microcephaly

UNMC researcher aims to find workable solution for tackling antibiotic resistance

UNMC researcher aims to find workable solution for tackling antibiotic resistance

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

Study highlights role of CMV in patients with leukemia after bone marrow transplantation

Study highlights role of CMV in patients with leukemia after bone marrow transplantation

Disrupted fetal immune system increases later risk of neurodevelopmental diseases

Disrupted fetal immune system increases later risk of neurodevelopmental diseases

T memory cells with naive phenotype can help boost immunity in older adults

T memory cells with naive phenotype can help boost immunity in older adults

New study identifies PDGFRα as key molecule for HCMV viral entry

New study identifies PDGFRα as key molecule for HCMV viral entry

Positive effects of Mediterranean diet on health of elderly population

Positive effects of Mediterranean diet on health of elderly population

New study to explore outcomes of pregnancy in Brazilian women with Zika virus

New study to explore outcomes of pregnancy in Brazilian women with Zika virus

NAU researcher calls for greater public awareness of cytomegalovirus

NAU researcher calls for greater public awareness of cytomegalovirus

CMV-based vaccine provides protection against Ebola virus

CMV-based vaccine provides protection against Ebola virus

Roche's cobas HIV-1 viral load test approved by FDA for use on cobas 6800 and cobas 8800 Systems

Roche's cobas HIV-1 viral load test approved by FDA for use on cobas 6800 and cobas 8800 Systems

Self-disseminating vaccines could prevent EID transmission from animals to humans

Self-disseminating vaccines could prevent EID transmission from animals to humans

First primate model can help researchers to study mother-to-fetus CMV infections

First primate model can help researchers to study mother-to-fetus CMV infections

FDA permits marketing of first CSF nucleic acid-based test for detection of multiple pathogens

FDA permits marketing of first CSF nucleic acid-based test for detection of multiple pathogens

Donor and patient age more important in determining kidney transplant success

Donor and patient age more important in determining kidney transplant success

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