Cytoskeleton News and Research

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Neuropathic pain study uncovers pathophysiological mechanism and promising therapeutic target

Neuropathic pain -; abnormal hypersensitivity to stimuli -; is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV.

5 May 2023

TiY: Cancer diagnosis and treatment in a single step

Cancer is not incurable anymore. Nevertheless, according to statistics released by Statistics Korea last year, cancer remained the primary cause of mortality in Korea in 2021.

4 Apr 2023

Discovery enables a clear diagnosis for more patients with androgen insensitivity syndrome

Steroid hormones, to which belong sex hormones like estrogen or testosterone, are important signaling molecules and are responsible among other things for controlling female and male phenotypic sex differentiation.

27 Mar 2023

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

A new preprint examines the response to these pathogens in the nose, which is the primary portal of entry for both.

13 Mar 2023

Researchers unlock the molecular basis behind fastest biological movement of single-celled eukaryotes

In his famous letter to the Royal Society dated Oct. 9, 1676, Antonie van Leeuwenhoek described a single-celled eukaryote (Vorticella) and its fascinating ultrafast cell contraction as the first set of discoveries.

22 Feb 2023

Centrosome regulates nerve cell migration, study finds

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

15 Feb 2023

Study reveals mechanism of a previously unexplained type of cell death

A study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Cell Biology, details a previously unexplained type of cell death called disulfidptosis that could open the door for novel cancer therapeutic strategies.

6 Feb 2023

Actin influences cancer metastases in many ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues.

31 Jan 2023

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide.

27 Jan 2023

Scientists reveal how genetic changes lead to differences in the size of cancer cells

Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered.

25 Jan 2023

Researchers explore the mechanism involved in the living world’s fastest cell movements

Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes commonly found in fresh, brackish, and sea water.

18 Jan 2023

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Researchers discovered that the elevated expression of LAP1, an inner nuclear membrane protein, helps metastatic melanoma cells surmount the physical challenges presented by tissue structure and the microenvironment during metastasis.

11 Jan 2023

Zebrafish models shed light on Shigella infection

In this interview, NewsMedical speaks with Professor Serge Mostowy and Sydney Miles about their research on bacterial infection, and, in particular, on Shigella Flexneri and enteropathogens.

From IDEA Bio-Medical Ltd. 6 Dec 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Health of mothers, fetuses, and children are all affected by the maternal environment

A recent editorial published in the journal BMC Medicine examined existing literature for associations between the mother's and offspring's health outcomes and a broad range of maternal characteristics related to pregnancy and postnatal phenotypes and complications.

3 Nov 2022

Cytoskeleton News and Research

Neuropathic pain study uncovers pathophysiological mechanism and promising therapeutic target

TiY: Cancer diagnosis and treatment in a single step

Discovery enables a clear diagnosis for more patients with androgen insensitivity syndrome

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

Researchers unlock the molecular basis behind fastest biological movement of single-celled eukaryotes

Centrosome regulates nerve cell migration, study finds

Study reveals mechanism of a previously unexplained type of cell death

Actin influences cancer metastases in many ways

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Scientists reveal how genetic changes lead to differences in the size of cancer cells

Researchers explore the mechanism involved in the living world’s fastest cell movements

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Zebrafish models shed light on Shigella infection

The effects of mechanical forces on musculoskeletal cells and tissues

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Health of mothers, fetuses, and children are all affected by the maternal environment

Higher viscosity of extracellular fluid enhances cancer dissemination

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Newly identified process keeps some immune cells on their toes

UW joins the Alliance for Therapies in Neuroscience to transform the fight against neurological diseases

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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