Cytotoxicity News and Research

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New method offers insights into mechanisms of staphylococcal pathogenesis

Nearly one in three people globally unknowingly carries Golden staph, or Staphylococcus aureus, in their nose or on their skin. While the bacterium is harmless to most, it can lead to serious infection and even death if it enters the bloodstream through a cut, surgical wound or catheter.

16 Jun 2023

Bergamot fiber shows promise in battling neurodegenerative disorders

Bergamot fiber (BF), a byproduct of citrus fruit processing, shows antioxidant properties and protects against neurotoxicity induced by amyloid beta protein (Aβ), suggesting potential benefits for Alzheimer's disease treatment and waste reduction.

13 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Endophytic fungi Penicillium verhagenii: an exploration of its anticancer, antioxidant, antimicrobial, and larvicidal activity

Researchers explored the use of endophytic fungi to fabricate selenium nanoparticles.

6 Jun 2023

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

Energy drinks may stunt muscle repair, new study suggests

Energy drinks impede muscle regeneration and reduce physical performance. This study provided evidence of an inhibitory effect on myogenic differentiation and highlighted potential concerns for athletes and fitness enthusiasts.

29 May 2023

Penn State researchers create first protein-based nano-computing agent

The first protein-based nano-computing agent that functions as a circuit has been created by Penn State researchers.

26 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Study suggests SARS-CoV-2 vaccination in pregnancy induces diverging maternal and infant cord antibody functions

Researchers explored the differences in infant and maternal cord antibody functions between SARS-CoV-2 infection and vaccination during pregnancy.

4 May 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Chemists discover novel, highly effective anticancer agents with tridimensional structures

A research team co-led by chemists from City University of Hong Kong recently discovered novel, highly effective anticancer agents with tridimensional structures, which have high anticancer activity, low toxicity and the ability to overcome drug resistance in cancer cells.

7 Apr 2023

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

Researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin.