Cytotoxicity News and Research

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Multiplexed STED nanoscopy technique reduces photobleaching and phototoxicity in live-cell imaging

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2024.240035 discusses multiplexed stimulated emission depletion nanoscopy for multi-color live-cell long-term imaging.

23 Jul 2024

Hydrogel implant technology offers new hope for women seeking reversible sterilization and endometriosis treatment

Hydrogel implants for reversible fallopian tube occlusion, providing contraception and preventing endometriosis.

19 Jul 2024

Pioneering Live Cell Imaging - Yokogawa's Impact and Innovations

In this interview, NewsMedical speaks with Kevin Jan from Yokogawa about the future of live cell imaging technologies.

From Yokogawa Life Science 3 Jul 2024

Ethanolic extracts from olive leaves show promise in combating cancer and infections

A recent study in Antioxidants reveals that ethanolic extracts from Greek and Spanish olive leaves exhibit high antioxidant, antimicrobial, and anticancer properties, with Greek extracts showing greater efficacy. This suggests potential healthcare applications, particularly as antimicrobial agents and melanoma treatments.

30 Jun 2024

How micro- and nanoplastics may worsen non-communicable diseases

Researchers review and assess the potential exacerbation of non-communicable diseases by micro- and nanoplastics.

21 Jun 2024

Ethiopian medicinal plants show promise in cervical cancer research

Research focused on collecting and analyzing plants native to Ethiopia is showing promise in the fight against cancer -; specifically cervical cancer cells.

18 Jun 2024

Deep learning revives ancient peptides to battle antibiotic resistance

Researchers used deep learning to resurrect antibiotic peptides from extinct organisms, offering new solutions for combating antibiotic resistance.

12 Jun 2024

Synergistic cytotoxicity in pancreatic cancer: HDAC, PARP inhibitors, and decitabine show promise

A new research paper was published in Oncotarget's Volume 15 on June 3, 2024, entitled, "Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy."

5 Jun 2024

New type of immunotherapy shows promising preclinical results against osteosarcoma

A new type of immunotherapy, developed by UCL researchers, has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.

29 May 2024

Tailoring polymeric micelles for improved olaparib solubility and drug release

Olaparib is a selective poly (ADP-ribose) polymerase inhibitor. However, its clinical application is hindered by low solubility and undesired pharmacokinetic profiles (e.g., relatively short circulation).

23 May 2024

Impact of CLK kinase inhibitors 1C8 and GPS167 on cancer cell proliferation and metastasis

A new research paper was published in Oncotarget's Volume 15 on May 16, 2024, entitled, "The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response."

20 May 2024

Curcuminoid compounds show promise against COVID-19 in neuronal cells

The effects of curcumin and curcuminoids on a human neuroblastoma cell line (SH-SY5Y) infected with SARS-CoV-2.

14 May 2024

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Researchers discovered that venom toxins from African spitting cobras cause severe dermonecrosis, highlighting the need for targeted treatments like the repurposed drug varespladib.

9 May 2024

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

Compound 12: A promising candidate for heart failure therapy with reduced glucose-lowering activity

Prior research showed that thoughtful structural modifications can dissociate the anti-heart failure activity from glucose-lowering effects.

8 May 2024

New influenza vaccine strategies aim to enhance protection with T-cell responses

A recent review highlights the need for innovative influenza vaccines that combine T-cell and antibody responses to enhance protection across multiple strains and seasons.

6 May 2024

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Vaccine-based therapeutics for age-related disorders.

17 Apr 2024

Study shows potential for universal flu vaccine with broad antibody response

Study discusses the potential of universal influenza vaccines, emphasizing the importance of antibody breadth and Fc receptor (FcR) effector functions in protecting against various influenza strains, including those with pandemic potential.

15 Apr 2024

Therapeutic potential of CD20 x CD3 bispecific antibodies

On Monday, March 25th, 2024, the U.S. FDA declined approval for Regeneron’s Odronextamab for two forms of lymphoma due to concerns over the progress of ongoing confirmatory trials.

From Sino Biological Inc. 5 Apr 2024

Study highlights anti-inflammatory properties of herbal medicine, Erigeron breviscapus to treat osteoarthritis

Researchers explored using Erigeron breviscapus (EB) as a treatment for osteoarthritis (OA).

4 Apr 2024