Cytotoxicity News and Research

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The binding and functional serologic responses to COVID-19 vaccination in children with history of MIS-C

Researchers evaluated the serological responses elicited by COVID-19 vaccinations in children who developed MIS-C following a previous SARS-CoV-2 infection.

23 Nov 2022

New method for isolating Omicron subvariant and evaluating resistance to therapeutic and vaccine-elicited antibodies

Researchers demonstrated a viral amplification procedure to isolate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

21 Nov 2022

CAR T-cell therapy in colorectal cancer

Researchers assessed the efficacy of CAR T-cells in the immunotherapy of colorectal cancer.

21 Nov 2022

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

A recent study demonstrated a novel method for delivering anti-cancer drugs, conjugated to modified cell-penetrating peptides across the blood-brain barrier, in mice to treat glioblastoma.

18 Nov 2022

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Researchers assessed the impact of drug combinations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suppression.

14 Nov 2022

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Researchers assessed the effect of fenofibrate on acute COVID-19.

9 Nov 2022

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

8 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

CHG may be the most effective irrigation solution for use during surgical treatment of bone tumors

The widely used disinfectant chlorhexidine gluconate (CHG) appears to be the most effective irrigation solution for use as part of the surgical treatment of bone tumors, suggests an experimental study in The Journal of Bone & Joint Surgery.

28 Oct 2022

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers investigated whether immunity against seasonal human coronavirus spike proteins of HKU1, OC43, NL63, or 229E could protect against SARS-CoV-2 in vitro.

28 Oct 2022

Researchers design a COVID-19 vaccine construct using hybrid SARS-CoV-2 spike protein and nucleocapsid protein peptides

Researchers designed a COVID-19 vaccine construct using hybrid SARS-CoV-2 S protein (containing SARS-CoV-2 Delta and Omicron variant mutations) and N protein peptides that confer T lymphocyte-mediated immune protection.

25 Oct 2022

Review on COVID-19 biomedical waste-derived microplastic toxicity

In a new study, researchers reviewed existing literature on the biomedical waste source, elements, and the recent upsurge of microplastics during the SARS-CoV-2 pandemic.

11 Oct 2022

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

In a new study, researchers investigated the breadth and longevity of immunity induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure among the Kenyan population.

10 Oct 2022

Vaccine-induced neutralizing and non-neutralizing antibody activity against SARS-CoV-2

A new study demonstrated that vaccine-induced antibody functions against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diminish with age.

7 Oct 2022

Researchers report aminoadamantanes that block SARS-CoV-2 infection by S-nitrosylation of the host ACE2 protein

Researchers investigated the use of aminoadamantane nitrate compounds as anti-SARS-CoV-2 drugs.

3 Oct 2022

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

In a recent study posted to the bioRxiv* preprint server, researchers in Australia explored the molecular mechanisms of the pulmonary and cardiac complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using human stem-cell-derived cardiac and lung cells.

27 Sep 2022

Cytotoxicity News and Research

The binding and functional serologic responses to COVID-19 vaccination in children with history of MIS-C

New method for isolating Omicron subvariant and evaluating resistance to therapeutic and vaccine-elicited antibodies

CAR T-cell therapy in colorectal cancer

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Study identifies novel inhibitors against SARS-CoV-2 main protease

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

CHG may be the most effective irrigation solution for use during surgical treatment of bone tumors

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers design a COVID-19 vaccine construct using hybrid SARS-CoV-2 spike protein and nucleocapsid protein peptides

Review on COVID-19 biomedical waste-derived microplastic toxicity

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

Vaccine-induced neutralizing and non-neutralizing antibody activity against SARS-CoV-2

Researchers report aminoadamantanes that block SARS-CoV-2 infection by S-nitrosylation of the host ACE2 protein

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

In vitro gut models reveal how microplastics affect the GI tract

Vaccination drives superior functional antibody breadth compared to natural infection with SARS-CoV-2

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

Forensics And Toxicology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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