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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Almac's main research projects on ovarian, breast cancer to be presented at ASCO 2011

Two of Almac's main research projects have been selected for presentation at the 2011 ASCO meeting. Both of these studies are based on Almac's approach of profiling large clinical datasets and analysing the data for molecular subgroups that can aid in improved diagnosis of cancer by identifying molecular subtypes and by identifying molecular subgroups which are of clinical and therapeutic relevance.

31 May 2011

Study: E-waste linked to adverse effects on human health

In addition to its damaging effect on the environment and its illegal smuggling into developing countries, researchers have now linked e-waste to adverse effects on human health, such as inflammation and oxidative stress - precursors to cardiovascular disease, DNA damage and possibly cancer.

31 May 2011

Mouse Phylogeny Viewer

Laboratory research has always been limited in terms of what conclusions scientists can safely extrapolate from animal experiments to the human population as a whole. Many promising findings in mice have not held up under further experimentation, in part because laboratory animals, bred from a limited genetic foundation, don't provide a good representation of how genetic diversity manifests in the broader human population.

30 May 2011

Pre-implantation genetic diagnosis can avoid mother to child transmission of mtDNA disorders

Dutch researchers have developed a test which predicts which mothers at risk of passing on mitochondrial genetic disease to their children are likely to have a healthy baby.

30 May 2011

JRC report shows how molecular technologies can help combat illegal fishing, support traceability

Low-cost catfish fillets sold as expensive sole fillets or cod caught in the North Sea but declared as originating from the Baltic Sea are both examples of types of fraud in the fisheries sector. A European Commission report published today shows how molecular technologies - based on genetics, genomics, chemistry and forensics - can provide clear answers to questions such as "what species does this fish product come from….where was this fish caught….is it wild or farmed?".

30 May 2011

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

5% to 10% of all breast cancers are monogenic in origin. In other words, there is a mutation of the genes BRCA1, BRCA2 or other high-risk genes. In this edition of Deutsches Ärzteblatt International, Alfons Meindl of the Klinikum rechts der Isar and coauthors report on new insights into the pathogenesis and treatment of hereditary breast and ovarian cancer and newly-discovered risk genes.

30 May 2011

IT-IS Life Sciences, Roche sign exclusive distribution agreement for new LightCycler Nano Instrument

Roche Applied Science has signed a worldwide exclusive OEM agreement with IT-IS Life Sciences Ltd for the distribution of the new LightCycler Nano Instrument, which will complete the company´s portfolio for the low throughput real-time PCR systems market.

30 May 2011

Possible defense for community-acquired pneumonia among the elderly

Community-acquired pneumonia is the leading cause of infectious death among the elderly. Newly published research from The University of Texas Health Science Center San Antonio suggests why older people are vulnerable and offers a possible defense.

27 May 2011

DNA-based traceability system tracks beef

Starting today, 11,000 U.S. restaurants that serve Braveheart Black Angus Beef will be able to assure diners a guarantee of quality about their premium Angus beef through DNA TraceBack®, the nation's first-of-its-kind assurance of quality and commitment.

27 May 2011

Lactate shuttle also exists in human tumors

Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow-and how to make it stop. Interestingly, cancer cells accelerate the aging of nearby connective tissue cells to cause inflammation, which ultimately provides "fuel" for the tumor to grow and even metastasize.

27 May 2011

BioDiscovery, Affymetrix enter co-marketing agreement for OncoScan FFPE Express Service

Affymetrix, Inc. today announced a co-marketing agreement naming BioDiscovery, Inc. its preferred software provider for Affymetrix OncoScan FFPE Express Service data analysis.

27 May 2011

'Spongy' silicon biosensor shows promise for medical, security applications

Vanderbilt University engineers have created a "spongy" silicon biosensor that shows promise not only for medical diagnostics, but also for the detection of dangerous toxins and other tiny molecules in the environment.

27 May 2011

Leukemia, psoriasis drugs may treat vascular diseases

A drug that has been on the market for decades to treat leukemia and skin disorders such as acne and psoriasis may be a possible therapy for vascular diseases, including atherosclerosis and hypertension, which can lead to heart attack or stroke.

27 May 2011

ARCA plans to expand development program for Gencaro in atrial fibrillation

ARCA biopharma, Inc., a biopharmaceutical company developing genetically-targeted therapies for cardiovascular diseases, today announced that it is planning to expand the development of Gencaro, its lead cardiovascular drug candidate, to atrial fibrillation, a disease that affects more than 2.4 million patients in the United States.

27 May 2011

Berkeley Lab researchers aim to create biological circuits for synthetic biology

Taking a page from the book of San Francisco radio legend Scoop Nisker, biologists who find themselves dissatisfied with the microbes nature has provided are going out and making some of their own. Members of the fast-growing "synthetic biology" research community are designing and constructing novel organisms and biologically-inspired systems - or redesigning existing organisms and systems - to solve problems that natural systems cannot.

27 May 2011

Folic acid during pregnancy reduces rate of colon cancer in offspring

Folic acid supplements given to pregnant and breast-feeding rats reduced the rate of colon cancer in their offspring by 64 per cent, a new study has found.

27 May 2011

Tigris Pharmaceuticals begins enrollment in AFP-464 Phase 2 trial in ER-positive breast cancer

Tigris Pharmaceuticals, Inc., today announced enrollment of its first patient in a randomized Phase 2 clinical trial of AFP-464 with or without Faslodex in estrogen receptor (ER)-positive breast cancer patients.

27 May 2011

Gestational high-fat diet programs woman's baby for future diabetes

A high-fat diet during pregnancy may program a woman's baby for future diabetes, even if she herself is not obese or diabetic, says a new University of Illinois study published in the Journal of Physiology.

26 May 2011

Boehringer Ingelheim's new afatinib-cetuximab phase Ib data in NSCLC presented at ASCO 2011

Boehringer Ingelheim Pharmaceuticals, Inc. will present new phase Ib data at the 2011 American Society of Clinical Oncology annual meeting in Chicago that indicates combining its investigational therapy afatinib with cetuximab at the maximum tested dose controlled disease in all (n=22) treated epidermal growth factor receptor (EGFR)-mutation positive patients with non-small cell lung cancer who developed acquired resistance to treatment with a reversible EGFR tyrosine kinase inhibitor.

26 May 2011

AIBioTech works with U.S. FDA to keep Sports X Factor genetic test available to consumers

American International Biotechnology Services today announced it is working with the U.S. Food and Drug Administration to keep its Sports X Factor genetic test available to consumers.

26 May 2011

DNA News and Research

Further Reading

Almac's main research projects on ovarian, breast cancer to be presented at ASCO 2011

Study: E-waste linked to adverse effects on human health

Mouse Phylogeny Viewer

Pre-implantation genetic diagnosis can avoid mother to child transmission of mtDNA disorders

JRC report shows how molecular technologies can help combat illegal fishing, support traceability

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

IT-IS Life Sciences, Roche sign exclusive distribution agreement for new LightCycler Nano Instrument

Possible defense for community-acquired pneumonia among the elderly

DNA-based traceability system tracks beef

Lactate shuttle also exists in human tumors

BioDiscovery, Affymetrix enter co-marketing agreement for OncoScan FFPE Express Service

'Spongy' silicon biosensor shows promise for medical, security applications

Leukemia, psoriasis drugs may treat vascular diseases

ARCA plans to expand development program for Gencaro in atrial fibrillation

Berkeley Lab researchers aim to create biological circuits for synthetic biology

Folic acid during pregnancy reduces rate of colon cancer in offspring

Tigris Pharmaceuticals begins enrollment in AFP-464 Phase 2 trial in ER-positive breast cancer

Gestational high-fat diet programs woman's baby for future diabetes

Boehringer Ingelheim's new afatinib-cetuximab phase Ib data in NSCLC presented at ASCO 2011

AIBioTech works with U.S. FDA to keep Sports X Factor genetic test available to consumers

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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