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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Chromatrap Pro-A Spin Columns improve ChIP assay performance

Porvair Filtration Group has announced the launch of the first product, a ChIP kit containing 24 assays, based upon its novel Chromatrap™ Pro-A Chromatin ImmunoPrecipitation (ChIP) technology. The exciting new product has been enthusiastically tested at 12 beta sites around the world with excellent results and feedback.

From Chromatrap® - Porvair Sciences Ltd 3 May 2011

Althea enters commercial drug supply agreement with Biotest

Althea Technologies, Inc. announced today that they have entered into a commercial supply agreement with Biotest Pharmaceuticals Corporation.

3 May 2011

Eurotrans-Bio awards 1.1 million grant to MDxHealth, NovioGendix for bladder cancer program

MDxHealth SA, a leading molecular diagnostics company in the field of personalized cancer treatment, today announced that together with partner NovioGendix B.V., a molecular diagnostics company spun out from Radboud University Nijmegen Medical Centre, the Netherlands, has received a USD 1.1 million grant from Eurotrans-Bio to progress its bladder cancer program.

3 May 2011

Scientists identify biochemical abnormality behind Machado-Joseph disease

Scientists in Portugal have identified a biochemical abnormality behind the potentially fatal neurodegenerative Machado-Joseph disease and using several models of the disease were able to reverse the problem in what can be a crucial step towards a cure for humans .

2 May 2011

New method helps scientists to determine specific protein molecular structure

The structures of many protein molecules remain unsolved even after experts apply an extensive array of approaches. An international collaboration has led to a new, high-performance method that rapidly determined the structure of protein molecules in several cases where previous methods had failed.

2 May 2011

Researchers discover two mutations responsible for neurological condition

Mayo Clinic researchers have discovered two mutations responsible for a devastating neurological condition they first identified 15 years ago. The researchers say their study -- appearing in Nature Genetics -- has revealed a new neural pathway that may help understand a variety of similar conditions.

2 May 2011

SaneVax criticizes FDA for approval of Roche's cobas HPV genotyping test

In an April 22, 2011 letter to FDA Commissioner; Dr. Margaret Hamburg, Norma Erickson on behalf of the SaneVax Inc. Board of Directors, criticized the FDA for not following its own guidelines and recommendations in approving Roche's cobas HPV Test for cervical cancer screening and for HPV-16 and HPV-18 genotyping.

30 Apr 2011

UCLA study findings hold promise to cure diabetes

Simply put, people develop diabetes because they don't have enough pancreatic beta cells to produce the insulin necessary to regulate their blood sugar levels.

30 Apr 2011

Centocor Ortho Biotech Products withdraws NDA for trabectedin for treatment of women with ROC

Centocor Ortho Biotech Products, L.P., today announced that it has voluntarily withdrawn the New Drug Application for trabectedin for the treatment of women with recurrent ovarian cancer. The withdrawal is based on the U.S. Food and Drug Administration's recommendation that an additional Phase 3 study be conducted to obtain approval.

30 Apr 2011

Study finds association between ERBB4 gene, LVOT malformations

A gene known to be important in cardiac development has been newly associated with congenital heart malformations that result in obstruction of the left ventricular outflow tract. These are the findings from a study conducted by Nationwide Children's Hospital and appearing in the journal Birth Defects Research Part A.

30 Apr 2011

Researchers unravel mechanism behind sickle hemoglobin protection against malaria

The latest issue of the journal Cell carries an article that is likely to help solve one of the long-standing mysteries of biomedicine. In a study that challenges currently held views, researchers at the Instituto Gulbenkian de Ci-ncia, in Portugal, unravel the molecular mechanism whereby sickle cell hemoglobin confers a survival advantage against malaria, the disease caused by Plasmodium infection.

29 Apr 2011

Portuguese researcher to earn Bill & Melinda Gates Foundation award for new HIV therapy

João Gonçalves, from Faculdade de Farmácia e Instituto de Medicina Molecular, Lisbon, Portugal, to win a Grand Challenges Exploration Award

29 Apr 2011

New PET imaging clinical trial to improve early esophageal, lung cancer detection

Can a simple imaging test help predict the success of cancer treatment, even before the treatment is complete? To begin to answer this question, a new National Cancer Institute-funded clinical trial is using a novel PET imaging technique that could improve the early detection of tumor growth during treatment for esophageal and lung cancer.

29 Apr 2011

DNA structure co-discoverer to present 'Curing Incurable Cancer' at Uofl event

James D. Watson, Ph.D., winner of the 1962 Nobel Prize with Francis Crick and Maurice Wilkins for the discovery of the double helical structure of DNA, will present "Curing Incurable Cancer" and attend other events associated with the Kentucky Derby. Watson's appearances are sponsored by the James Graham Brown Cancer Center at the University of Louisville.

28 Apr 2011

Hepatitis B virus rebound common in patients receiving nucleoside analogs for chronic hepatitis B

A rebound of the Hepatitis B virus is common in patients receiving nucleoside analogs for chronic hepatitis B, according to a study from U-M hepatologists. But nearly 40% of the rebounds or virological breakthroughs (VBTs) were not related to antiviral drug resistance.

28 Apr 2011

GSN receives NIH grant for non-invasive prenatal test trial in genetic abnormalities

Gene Security Network announced today that they have received a $2 million grant from the National Institutes of Health to conduct a clinical trial applying Parental Support technology for non-invasive prenatal diagnosis.

28 Apr 2011

Simple home genetic test can identify health risk factors in young athletes

It's a simple home genetic test, but the results it produces can make workouts more effective, children's sports choices more appropriate and trainers' awareness of potential risk factors more precise.

28 Apr 2011

Scientists identify new risk gene variant for depression

Max Planck scientists uncover surprising genetic links. Scientists from the Max Planck Institute for Psychiatry in Munich have compared the genomes of a total of 4,088 patients and 11,001 healthy control subjects from all over the world and identified a new risk gene variant for depression.

28 Apr 2011

MIT develops new software to predict complex 3-D DNA structures

While the primary job of DNA in cells is to carry genetic information from one generation to the next, some scientists also see the highly stable and programmable molecule as an ideal building material for nanoscale structures that could be used to deliver drugs, act as biosensors, perform artificial photosynthesis and more.

28 Apr 2011

Affymetrix reports total revenue of $73.7 million for first quarter 2011

Affymetrix, Inc., today reported its operating results for the first quarter of 2011. Total revenue for the quarter was $73.7 million, as compared to total revenue of $80.2 million in the first quarter of 2010.

28 Apr 2011

DNA News and Research

Further Reading

Chromatrap Pro-A Spin Columns improve ChIP assay performance

Althea enters commercial drug supply agreement with Biotest

Eurotrans-Bio awards 1.1 million grant to MDxHealth, NovioGendix for bladder cancer program

Scientists identify biochemical abnormality behind Machado-Joseph disease

New method helps scientists to determine specific protein molecular structure

Researchers discover two mutations responsible for neurological condition

SaneVax criticizes FDA for approval of Roche's cobas HPV genotyping test

UCLA study findings hold promise to cure diabetes

Centocor Ortho Biotech Products withdraws NDA for trabectedin for treatment of women with ROC

Study finds association between ERBB4 gene, LVOT malformations

Researchers unravel mechanism behind sickle hemoglobin protection against malaria

Portuguese researcher to earn Bill & Melinda Gates Foundation award for new HIV therapy

New PET imaging clinical trial to improve early esophageal, lung cancer detection

DNA structure co-discoverer to present 'Curing Incurable Cancer' at Uofl event

Hepatitis B virus rebound common in patients receiving nucleoside analogs for chronic hepatitis B

GSN receives NIH grant for non-invasive prenatal test trial in genetic abnormalities

Simple home genetic test can identify health risk factors in young athletes

Scientists identify new risk gene variant for depression

MIT develops new software to predict complex 3-D DNA structures

Affymetrix reports total revenue of $73.7 million for first quarter 2011

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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