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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Inovio publishes scientific paper detailing SynCon DNA vaccine preclinical study for prostate cancer

Inovio Pharmaceuticals, a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today the publication of a scientific paper in the journal Human Vaccines detailing potent immune responses in a preclinical study of Inovio's SynCon DNA vaccine for prostate cancer targeting two antigens.

2 Feb 2011

Defective nucleoli linked to Parkinson's disease

"Nucleolus", or small nucleus, is the term coined by early biologists for the tiny structure within the nucleus which they saw under the microscope. In this structure within the nucleus, RNA molecules and proteins are assembled to form ribosomes, the true protein factories of cells.

2 Feb 2011

Researchers find better way to create iPS cells from blood samples

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem cells-adult cells reprogrammed with the properties of embryonic stem cells-from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation.

2 Feb 2011

CDH first hospital in New England to use Xenex PX-UV disinfection system

Cooley Dickinson Hospital (CDH) today announced it is the first hospital in New England to use the Xenex PX-UV disinfection system to disinfect its patient and operating rooms.

2 Feb 2011

Intrexon announces AgBio Division launch and Agarigen acquisition

Intrexon Corporation, a next generation synthetic biology company, today announced the launch of its Agricultural Biotechnology (AgBio) Division in Research Triangle Park, North Carolina and the acquisition of Agarigen, Inc., a North Carolina-based company that has developed a novel, mushroom-based expression platform for the rapid, high yield production of recombinant proteins.

2 Feb 2011

EA sponsors research grant to investigate specific cancers and kinase mutations

Expression Analysis today announced a jointly sponsored research grant for up to eight American Cancer Society Grantees to investigate and draw parallels between specific cancers and recurring mutations in specific kinases, using targeted genome sequencing.

2 Feb 2011

DRC processors running Smith-Waterman algorithm set new world record

DRC Computer Corporation (DRC), the leading innovator of dynamically reconfigurable processors, announces that it has achieved 9.4 trillion cell updates per second (TCUPS) running the Smith-Waterman algorithm with Affine gap model on the latest DRC Accelium coprocessors.

1 Feb 2011

USPTO Board of Patent Appeals rules in favor of Pacific Biosciences in case against Life Technologies

Pacific Biosciences of California, Inc. today announced that the Board of Patent Appeals and Interferences of the United States Patent and Trademark Office (USPTO) has rendered a decision in a previously announced patent interference provoked by Pacific Biosciences related to single molecule sequencing. The decision cancels all patent claims by Life Technologies Corporation involved in the interference.

1 Feb 2011

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

"Cornell Dots" - brightly glowing nanoparticles - may soon be used to light up cancer cells to aid in diagnosing and treating cancer. The U.S. Food and Drug Administration has approved the first clinical trial in humans of the new technology.

1 Feb 2011

Free radicals may damage eyes of patients with Fuchs Endothelial Corneal Dystrophy

Scientists have found that free radicals (unstable molecules that cause the death of cells as the body ages) may also cause the damage in the eyes of patients with Fuchs Endothelial Corneal Dystrophy (FECD), a hereditary disease that is one of the most common reasons for corneal transplants worldwide.

1 Feb 2011

Scientists devise safer way to create iPS cells

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem (iPS) cells-adult cells reprogrammed with the properties of embryonic stem cells-from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation.

1 Feb 2011

DNA Direct implements four new health plan clients for molecular diagnostic and genetic tests

DNA Direct, a wholly owned subsidiary of Medco Health Solutions, Inc. and a provider of guidance and decision support for genomic medicine, today announced four new health plan clients that are implementing DNA Direct's Policy & Benefit Support Program for molecular diagnostic and genetic tests.

1 Feb 2011

Simple hTERT analysis may provide useful prognostic tool in advanced non-small cell lung cancer

High levels of circulating DNA may indicate faster progression of lung cancer and lower overall survival, according to a study published in the February edition of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer (IASLC).

1 Feb 2011

Scientists to commence new DNA vaccine trial for use in patients with leukemia

A new cancer treatment which strengthens a patient's immune system and enables them to fight the disease more effectively is being trialled on patients for the first time in the UK. The treatment will use a new DNA vaccine, developed by scientists from the University of Southampton, which will treat a selected group of volunteers who have either chronic or acute myeloid leukaemia - two forms of bone marrow and blood cancer.

31 Jan 2011

Inovio announces regulatory approval for Phase 2 trial to treat leukemia using new vaccine delivery device

Inovio Pharmaceuticals, a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today the regulatory approval of a Phase 2 clinical trial to treat leukemia utilizing Inovio's new ELGEN 1000 automated vaccine delivery device.

31 Jan 2011

Cohort Review Committee evaluates SCIB1 dose escalation, safety in Phase 1 trial

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, is pleased to announce that the first group of patients receiving the lowest dose of SCIB1 in the Phase I clinical trial has been evaluated by the Cohort Review Committee.

31 Jan 2011

EA receives CLIA certification for clinical laboratory testing

Expression Analysis, a leading provider of genomic services for clinical trials and research, announced today it has received CLIA certification. This milestone comes as the company enters its tenth year of providing genomic expertise; something the company refers to as "Genomic Know-How.

29 Jan 2011

Scientists use full genome sequencing to identify precise steps in molecular evolution of S. pneumoniae

Despite penicillin and the dozens of antibiotics that followed it, streptococcus bacteria have remained a major threat to health throughout the world. The reason: the superb evolutionary skills of this pathogen to rapidly alter its genetic makeup.

29 Jan 2011

NIH awards CCTSI $2.2 million grant to advance personalized medicine

A federal grant totaling $2.2 million shows how the University of Colorado School of Medicine and Anschutz Medical Campus are using technology to advance the cutting-edge field of personalized medicine -- tailoring treatments to the individual based on their genetic make-up.

28 Jan 2011

Preclinical data on Inovio’s intradermal electroporation delivery devices presented at Phacilitate Vaccine Forum

Inovio Pharmaceuticals, Inc., a leader in the development of novel therapeutic and preventive vaccines against cancers and infectious diseases, announced today the presentation of recent preclinical data using its next generation of minimally invasive intradermal (skin) electroporation delivery devices at the Phacilitate Vaccine Forum 2011 in Washington, DC.

28 Jan 2011

DNA News and Research

Further Reading

Inovio publishes scientific paper detailing SynCon DNA vaccine preclinical study for prostate cancer

Defective nucleoli linked to Parkinson's disease

Researchers find better way to create iPS cells from blood samples

CDH first hospital in New England to use Xenex PX-UV disinfection system

Intrexon announces AgBio Division launch and Agarigen acquisition

EA sponsors research grant to investigate specific cancers and kinase mutations

DRC processors running Smith-Waterman algorithm set new world record

USPTO Board of Patent Appeals rules in favor of Pacific Biosciences in case against Life Technologies

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

Free radicals may damage eyes of patients with Fuchs Endothelial Corneal Dystrophy

Scientists devise safer way to create iPS cells

DNA Direct implements four new health plan clients for molecular diagnostic and genetic tests

Simple hTERT analysis may provide useful prognostic tool in advanced non-small cell lung cancer

Scientists to commence new DNA vaccine trial for use in patients with leukemia

Inovio announces regulatory approval for Phase 2 trial to treat leukemia using new vaccine delivery device

Cohort Review Committee evaluates SCIB1 dose escalation, safety in Phase 1 trial

EA receives CLIA certification for clinical laboratory testing

Scientists use full genome sequencing to identify precise steps in molecular evolution of S. pneumoniae

NIH awards CCTSI $2.2 million grant to advance personalized medicine

Preclinical data on Inovio’s intradermal electroporation delivery devices presented at Phacilitate Vaccine Forum

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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