DNA Polymerase News and Research

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A DNA polymerase is an enzyme that catalyzes the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are most well-known for their role in DNA replication, in which the polymerase "reads" an intact DNA strand as a template and uses it to synthesize the new strand. The newly-polymerized molecule is complementary to the template strand and identical to the template's original partner strand. DNA polymerases use a magnesium ion for catalytic activity.

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Research investigates the potential health benefits of grape consumption by examining its impact on the human microbiome. By analyzing microbiome composition and metabolites, the study provides insights into the relationship between grapes and human health.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

Researchers pioneer a new method for fast miRNA amplification and detection

In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes.

24 Apr 2023

Mediterranean diet and the modulation of mitochondrial function

Researchers reviewed the current knowledge related to the Mediterranean diet (MedDiet) and the role of mitochondria concerning health outcomes.

7 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Researchers from Nigeria and the United Kingdom (U.K.) analyzed mpox virus genomes and found that divergent lineages of the mpox virus exhibiting human-to-human transmission existed in the Nigerian population before the 2022 spread of the virus outside of the endemic regions.

10 Jan 2023

New research on DNA-repair enzyme could help enhance cancer drug development

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could help make a particular enzyme a promising target for precision cancer therapy.

6 Jan 2023

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Researchers provided an overview of existing molecular methods for mpox virus detection.

13 Dec 2022

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and -; similar to COVID-19 -; mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more people.

4 Nov 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

Researchers reviewed the epidemiology, clinical character, treatment, and prevention of human monkeypox.

8 Sep 2022

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

A new review sheds light on the origins of this virus and recently acquired knowledge about its disease mechanism and the preventive and therapeutic measures appropriate in this situation.

31 Aug 2022

Würzburg scientists are working on the development of new drugs to combat monkeypox

Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows.

1 Aug 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Researchers investigate prevention and therapy against monkeypox infection

Researchers reviewed the preventive and therapeutic measures against monkeypox.

4 Jul 2022

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Researchers described potential mechanisms of coronaviruses that could lead to DNA damage and the potential link between SARS-CoV-2 activity and such mechanisms.

14 Jun 2022

New method increases efficiency of gene editing while minimizing DNA deletion sizes

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists working on CRISPR/Cas9-mediated gene editing technology have developed a method to increase efficiency of editing while minimizing DNA deletion sizes, a key step toward developing gene editing therapies to treat genetic diseases.

2 May 2022