DNA Synthesis News and Research

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Generative AI approach unlocks path to accelerated antibody drug creation for novel therapeutic targets

A recent study used generative AI models to develop de novo design antibodies against three distinct targets in a zero-shot fashion.

11 Jan 2023

New research on DNA-repair enzyme could help enhance cancer drug development

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could help make a particular enzyme a promising target for precision cancer therapy.

6 Jan 2023

New combination therapy shows potential to improve survival in children with neuroblastoma

Children who suffer a relapse of the aggressive cancer known as neuroblastoma have small chances of survival.

22 Aug 2022

Evonetix commences early access program for DNA synthesised by thermal control on its semiconductor chip

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform.

From Evonetix 16 Aug 2022

Drugs with antiviral activity against monkeypox virus

In a recent study posted as an accepted manuscript in the journal Clinical Infectious Diseases, researchers from the University of Oklahoma described three drugs with antiviral activity against the monkeypox virus (MPXV).

2 Aug 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Researchers described potential mechanisms of coronaviruses that could lead to DNA damage and the potential link between SARS-CoV-2 activity and such mechanisms.

14 Jun 2022

Evonetix appoints Colin McCracken as Chief Executive Officer

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced the appointment of Colin McCracken as Chief Executive Officer with immediate effect.

From Evonetix 14 Jun 2022

Investigating the role of cyclins and cyclin-dependent kinases in host restriction of SARS-CoV-2 infection

Researchers investigated COVID-19-triggered changes in the levels of cyclins and cyclin-dependent kinases inside host cells.

10 May 2022

Evonetix Granted Patent for Binary Assembly Method for Gene Synthesis

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced it has been granted a European patent covering its unique Binary Assembly method for gene synthesis.

From Evonetix 9 May 2022

RNA splicing abnormalities in COVID-19 patients

This study entailed the integration of multiple-omics datasets to examine the dysregulation in the host splicing mechanism and alteration in protein isoforms among COVID-19 patients.

20 Apr 2022

Evonetix granted patent for technology enabling thermally-controlled DNA synthesis

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced it has been granted patent EP3551331B1 in Europe for its proprietary thermal control technology for DNA synthesis, as well as the design and manufacture of its silicon chips.

From Evonetix 4 Apr 2022

Slowing down the DNA replication speed increases cell reprogramming efficiency

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only.

7 Mar 2022

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Glioblastoma is one of the deadliest cancers known to man. While the advent of immunotherapy and other cutting-edge treatments have prolonged life for people afflicted with other types of cancer, the prognosis for glioblastoma has remained relatively constant: just 18 months.

3 Oct 2021

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Twist Bioscience Corporation (Nasdaq: TWST) today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19.

25 Sep 2021

DNA Synthesis News and Research

Generative AI approach unlocks path to accelerated antibody drug creation for novel therapeutic targets

New research on DNA-repair enzyme could help enhance cancer drug development

New combination therapy shows potential to improve survival in children with neuroblastoma

Evonetix commences early access program for DNA synthesised by thermal control on its semiconductor chip

Drugs with antiviral activity against monkeypox virus

Is monkeypox a global public-health emergency?

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Evonetix appoints Colin McCracken as Chief Executive Officer

Investigating the role of cyclins and cyclin-dependent kinases in host restriction of SARS-CoV-2 infection

Evonetix Granted Patent for Binary Assembly Method for Gene Synthesis

RNA splicing abnormalities in COVID-19 patients

Evonetix granted patent for technology enabling thermally-controlled DNA synthesis

Slowing down the DNA replication speed increases cell reprogramming efficiency

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

New study identifies novel compound as promising pan-coronavirus drug candidate

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

A new method for efficient and automated production of synthetic DNA

Researchers define key questions to help the UK government for next biosecurity threat

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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