DNA Synthesis News and Research

RSS

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

During the DNA synthesis process in a laboratory, recordings can be made of the subtle, telltale noises made by synthesis machines. And those captured sounds can be used to reverse-engineer valuable, custom-designed genetic materials used in pharmaceuticals, agriculture and other bioengineering fields.

25 Feb 2019

Lab instruments may leak valuable information, finds study

Lab instruments are important tools throughout research and health care. But what if those instruments are leaking valuable information?

25 Feb 2019

Study reveals how the absence of Dna2 enzyme affects chromosome instability

Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication.

6 Dec 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

DNA Script successfully synthesizes world's first 150-nucleotide strand of DNA

DNA Script, the global leader in the development of enzymatic DNA synthesis, today announced that it has successfully synthesized the world's first 150-nucleotide strand of DNA by de novo enzymatic synthesis.

3 Oct 2018

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Nitrogen is a basic building block of all the body's proteins, RNA and DNA, so cancerous tumors are greedy for this element. Researchers at the Weizmann Institute of Science, in collaboration with colleagues from the National Cancer Institute and elsewhere, have now shown that in many cancers, the patient's nitrogen metabolism is altered, producing detectable changes in the body fluids and contributing to the emergence of new mutations in cancerous tissue.

13 Aug 2018

Timing may be key to evading destruction for bacteria facing antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment.

30 Jun 2018

Researchers report potential new role for skin bacteria in protecting against cancer

Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.

1 Mar 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

Scientists design new triple labeling technique to analyze stem cell division

A joint team of scientists from Russia and the United States designed a method for marking dividing stem cells with three different labels.

8 Feb 2018

Researchers show how rhythm of DNA replication can be manipulated to kill cancer cells

Human cells divide and create new cells throughout life. In this process, a steady – even rhythmic – supply of DNA building blocks is needed to create new DNA. Now researchers from the University of Copenhagen are the first to show exactly how human cells regulate this process so it does not fail and cause illness.

10 Nov 2017

Scientists uncover stem cell response to prolonged irradiation

Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells.

24 Aug 2017

Vitamin B3 supplementation during pregnancy may prevent birth defects, in-vivo study suggests

Supplementing the diet with vitamin B3 during pregnancy may treat the molecular deficiencies in women that can lead to birth defects, according to a landmark study in Australia. Over the last 12 years, developmental geneticist Sally Dunwoodie (Victor Chang Cardiac Research Institute, Sydney) and team have been studying the genes that influence fetal heart and bone development.

10 Aug 2017

Metabolomics and NMR

Bruker has been involved in the Phenome Center network since its beginning. Several years ago, the whole visionary concept of a global phenome network was actually born with Professor Jeremy Nicholson and Bruker BioSpin has been part of it since the early stages.

From Bruker BioSpin - NMR, EPR and Imaging 17 Jan 2017

Nexmos, Base Pair Biotechnologies create new class of DNA-aptamer based oxidation inhibitors

Base Pair Biotechnologies, Inc., The Aptamer Discovery Company, and Nexmos, Inc., the Aptamer Application R&D Company, announce the creation of a new class of DNA-aptamer based oxidation inhibitors.

30 Dec 2016

New database of PCR primers enables effective detection and identification of RNA viruses

Scientists at Korea's Daegu Gyeongbuk Institute of Science and Technology scientists have compiled a comprehensive new public database of genetic information to enable the detection and identification of RNA viruses using the polymerase chain reaction assay.

28 Dec 2016

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including Huntington's disease, myotonic dystrophy and forms of spinocerebellar ataxia.

6 Dec 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

Researchers develop new strategy to immunize against microbes that cause foodborne illness

University of California, Irvine and MIT researchers have developed a new strategy to immunize against microbes that invade the gastrointestinal tract, including Salmonella, which causes more foodborne illness in the United States than any other bacteria.

8 Nov 2016