Deafness News and Research

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New vaccine candidate shows promise for protecting against Lassa fever

Researchers from Thomas Jefferson University and the University of Maryland Baltimore, in collaboration with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) and the Geneva Foundation, have developed a promising new vaccine candidate that protects against Lassa fever.

12 Sep 2024

Magnetic nanoparticles may revolutionize drug delivery for hearing loss

Just as a business needs an effective and reliable service to deliver its goods to customers, medications need an effective delivery system to get them to the specific area of the body where they can have an impact.

19 Aug 2024

Study uncovers how TREM2 R47H mutation affects Alzheimer's plaques

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer's disease.

6 Aug 2024

Her hearing implant was preapproved. Nonetheless, she got $139,000 bills for months.

Caitlyn Mai woke up one morning in middle school so dizzy she couldn't stand and deaf in one ear, the result of an infection that affected one of her cranial nerves.

17 Jul 2024

Gene editing silences mutant microRNA, restores hearing in adult mice

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled the animals to regain hearing. The approach by a research team supported by the National Institutes of Health (NIH), reported in Science Translational Medicine, may eventually lead to potential treatments for inherited hearing loss in people.

13 Jul 2024

New gene editing technique offers hope for millions

A team led by Mass Eye and Ear researchers has demonstrated for the first time a successful restoration of hearing through a novel, in vivo genome editing approach in an adult mouse model with a form of inherited deafness caused by mutations in microRNA.

11 Jul 2024

Repurposing anti-retroviral medications for brain tumor treatment: The RETREAT trial

Drugs developed to combat HIV and AIDS are being trialed for the first time in patients with multiple brain tumors.

21 Jun 2024

Study sheds light on the rate and nature of mutations in mitochondrial DNA

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its maternal transmission.

7 Jun 2024

Gene therapy trial: restored hearing in children with hereditary deafness

The safety and effectiveness of binaural adeno-associated virus 1 (AAV1)-human otoferlin (hOTOF) therapy in five children with autosomal recessive deafness 9 (DFNB9).

7 Jun 2024

In utero brain overgrowth linked to severity of autism

Some children with autism experience profound, lifelong difficulties like developmental delay, social struggles and even the inability to speak.

5 Jun 2024

New bilateral gene therapy shows promising results in treating genetic hearing loss

A novel gene therapy designed to target a form of inherited deafness restored hearing function in five children who were treated in both ears.

5 Jun 2024

Infants exposed to more speech than music, UW study reveals

Speech and music are the dominant elements of an infant's auditory environment. While past research has shown that speech plays a critical role in children's language development, less is known about the music that infants hear.

30 May 2024

Weak brain circuit connection found to influence overeating and obesity

Why can some people easily stop eating when they are full and others can't, which can lead to obesity?

16 May 2024

Washington University expands STI testing and treatment services in St. Louis County

In a bid to improve sexual health and reduce health disparities in the St. Louis area, Washington University infectious diseases physicians are expanding testing and treatment services for sexually transmitted infections in north St. Louis County.

7 May 2024

Revolutionizing treatment for neurological conditions with 3D printed surgical implants

Clever bio-inks that sit inside the human body and restore damaged neurons could cure a whole swathe of diseases in the next 20 years: conditions that have baffled scientists and clinicians for centuries.

6 May 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).

10 Apr 2024

Sit less, live healthier: Trial shows blood pressure drops with less sitting

Whether reducing sitting time could effectively improve blood pressure (BP) among older adults.

29 Mar 2024

Discovering the on-switch for rare genetic inflammatory diseases

University of Queensland researchers have discovered how the 'on-switch' for the body's inflammation machinery can get stuck and cause rare genetic inflammatory diseases.

18 Mar 2024

Exome sequencing unravels complex genetic diagnoses in growth disorders

In an article published in the Journal of Pediatrics, researchers based in Brazil describe the case of a nine-year-old boy admitted to hospital with multiple symptoms and overlapping conditions that made diagnosis difficult, such as short stature, thin tooth enamel (dental enamel hypoplasia), moderate mental deficiency, speech delay, asthma, mildly altered blood sugar, and a history of recurring infections in infancy.

16 Feb 2024

First gene therapy trial aims to restore hearing in children

The aim of this clinical trial, which has just received approval in France, is to assess the safety and efficacy of a new gene therapy drug in children aged between 6 and 31 months with profound hearing loss.

5 Feb 2024