Dexamethasone News and Research

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Inflammation plays a key role in resolving pain

In a recent study published in the journal Science Translational Medicine, researchers explored the mechanisms underlying the transition from acute to chronic low back pain (LBP) by transcriptome-wide analysis of peripheral immune cells from acute LBP patients.

17 May 2022

CDC study of pregnant women hospitalized with COVID in 2021 found 93% not vaccinated

In a recent study posted to the Research Square* preprint server, researchers assessed the characteristics and treatment of coronavirus disease 2019 (COVID-19) in pregnant women.

12 May 2022

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Researchers assessed the efficacy and safety of using lithium for coronavirus disease 2019 (COVID-19) treatment.

5 May 2022

SARS-CoV-2 infection during pregnancy linked to adverse maternal outcomes and preterm birth

Since the coronavirus disease 2019 (COVID-19) pandemic was declared in 2020, there has been much concern over the effects of the disease on unborn children and pregnant women.

4 May 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Findings of the HITCH randomized clinical trial show lack of improvement in COVID-19 on temporary androgen suppression

Researchers investigated whether temporary androgen suppression by degarelix improved the clinical outcomes among male patients hospitalized with COVID-19.

27 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

Interleukin-6 levels predict early withdrawal of COVID-19 patients from mechanical ventilation

Researchers reported that plasma IL-6 levels in patients with ARDS due to COVID-19 could predict early withdrawal from mechanical ventilation.

22 Apr 2022

Why cheap, older drugs that might treat covid never get out of the lab

In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.

19 Apr 2022

Effects of COVID-19 treatment best with combination therapy

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

15 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

Study finds dexamethasone and remdesivir treatment in hospitalized COVID-19 patients is associated with reduced neurological complications

Researchers investigated the potential of therapeutic drugs, remdesivir and dexamethasone, when used alone or in combination on neurological complications that arise in COVID-19 affected individuals.

14 Apr 2022

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

A recent scientific statement published in Circulation reviewed the current knowledge on COVID-19.

13 Apr 2022

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications are uncommon, yet treatable for children and young adults after COVID-19 disease or SARS-CoV-2 infection, according to a new scientific statement from the American Heart Association that details what has been learned about how to treat, manage and even prevent cardiovascular complications from the SARS-CoV-2 virus in youth.

12 Apr 2022

Immunocompromised hosts with Delta/Omicron co-infections

A recent study posted to the medRxiv* preprint server examined clinical cases of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta/Omicron variants and Omicron BA.1/ BA.2 sublineages in immunocompromised (IC) patients.

10 Apr 2022

Study says duplilumab reduces mortality from COVID-19

A recent report posted to the medRxiv* preprint server assessed the efficacy of dupilumab in blocking the IL-13 signaling pathway and its efficacy in reducing the COVID-19 associated mortality.

5 Apr 2022

Value of information analysis on clinical trial data to help approve or reject new COVID-19 drugs

Researchers quantified the cost-effective health benefits of pursuing further research or approving or rejecting COVID-19 drugs based on the existing research using a novel method called VOI analysis.

4 Apr 2022

Hydrocortisone does not prevent bronchopulmonary dysplasia in preterm infants

Hydrocortisone is no more effective than placebo at preventing damage that can result from oxygen and ventilator therapy necessary to keep preterm infants alive, according to research funded by the National Institutes of Health.

23 Mar 2022

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.

21 Mar 2022

Croup: A previously unrecognized complication of COVID-19 in young children

The omicron surge has led to a previously unrecognized complication of COVID-19 in young children: croup. In the first peer-reviewed report to date, physicians at Boston Children's Hospital describe 75 children who came to the hospital's emergency department (ED) with croup and COVID-19 from March 1, 2020 through January 15, 2022.

15 Mar 2022