Disease Modeling News and Research

RSS

Mathematical model shows the influence of human behavior on spread of infectious diseases

Mathematics can help public health workers better understand and influence human behaviors that lead to the spread of infectious disease, according to a study from the University of Waterloo.

16 Aug 2018

Mature kidney podocytes for developing cell therapies and drug discovery

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body.

11 Jul 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Scientists discover way to increase efficiency of mature blood production in a dish

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a way to increase the efficiency of mature blood production in a dish.

29 Jun 2018

Study combines gene editing and stem cell technologies to predict person’s risk for heart disease

Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's journal Circulation.

18 Jun 2018

Gene editing technology predicts heart disease risk

Scientists could now use gene editing and stem cell technologies to predict whether carrying a specific gene variant increases the risk of heart disease.

18 Jun 2018

New 3D brain organoid may hold potential in drug discovery, disease modeling

Wake Forest Institute for Regenerative Medicine scientists have developed a 3D brain organoid that could have potential applications in drug discovery and disease modeling.

30 May 2018

Study: People showing no symptoms likely to be primary source of dengue fever

People showing virtually no symptoms are likely the primary source of dengue fever, according to new research published in PLOS Pathogens. Nearly 400 million people each year are infected with dengue virus, which is transmitted through mosquitoes.

4 May 2018

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

Astrocytes, the supporting cells of the brain, could play a significant role in the pathogenesis of Alzheimer's disease (AD), according to a new study from the University of Eastern Finland. This is the first time researchers discovered a direct association between astrocytes and AD. Published in Stem Cell Reports, the study investigated the brain cell function of familial AD patients by using stem cell technologies.

17 Nov 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

Time spent outdoors impacts risk for contracting Zika virus

When Zika first buzzed into the continental United States during the 2016 outbreak, Florida was hit first--and hardest--with 1,174 documented cases to date. So, when Marco Ajelli, associate research scientist at Northeastern and an expert in infectious disease modeling, wanted to study how time spent outside might affect the spread of the epidemic, he chose to focus on the state's most stricken county: Miami-Dade.

22 Sep 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

Netflix's ‘13 Reasons Why’ linked to increase in internet searches for suicide methods

If you haven't heard of Netflix's television series "13 Reasons Why," just ask the nearest teenager. They'll tell you it's an immensely popular show among their young-adult peers, depicting the anguish and eventual suicide of a teenage girl as experienced by a friend listening to the series of audio-cassette journal entries she left behind.

31 Jul 2017

Disease Modeling News and Research

Mathematical model shows the influence of human behavior on spread of infectious diseases

Mature kidney podocytes for developing cell therapies and drug discovery

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists discover way to increase efficiency of mature blood production in a dish

Study combines gene editing and stem cell technologies to predict person’s risk for heart disease

Gene editing technology predicts heart disease risk

New 3D brain organoid may hold potential in drug discovery, disease modeling

Study: People showing no symptoms likely to be primary source of dengue fever

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

Time spent outdoors impacts risk for contracting Zika virus

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

Id genes found to play crucial role in heart development

Netflix's ‘13 Reasons Why’ linked to increase in internet searches for suicide methods

Gene editing technology shines light on rare dyskeratosis congenita

Research shows key role of diffusion dynamics in stem cell differentiation and tissue development

Research team receives NIH grant to develop new way to examine cancer cell metastasis

Researchers recapitulate pathological condition of retinal diseases on a chip

Salk scientists discover chemical cocktail that enables stem cells to generate tissues

Stem cells strictly abide by innate developmental clocks, study shows

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News