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Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Will the FDA rise to the occasion and admit their natalizumab mistake?

When Anita Louise Smith enrolled in an experimental drug trial in 2002 in Colorado, she had a diagnosis of multiple sclerosis but no symptoms and was looking to reduce the chances of being ravaged by the disease.

7 Mar 2006

Genes play a key role in stress response

Both nature and nurture - genetic makeup and the environment experienced through life - combine to influence health and well-being, Duke University Medical Center researchers and their colleagues have determined in four new studies.

7 Mar 2006

Researchers discover cause of episodic ataxia type-2

Researchers at the Albert Einstein College of Medicine of Yeshiva University have discovered the underlying cause of a type of ataxia, hereditary disorders characterized by poor balance, loss of posture and difficulty performing rapid coordinated movement.

7 Mar 2006

Newly identified biomarkers may help reverse the ageing process

Lotions and potions that promise to remove wrinkles and other effects of aging crowd cosmetics aisle shelves, but do these treatments really work?

7 Mar 2006

Catheter ablation for chronic atrial fibrillation improves quality of life

People who have endured the effects and risks of an irregular heartbeat for years can get long-lasting relief from a procedure that takes less than two hours, a definitive new study shows.

7 Mar 2006

Pharmaceutical brochures don't always present accurate data

A study published in the journal BMC Family Practice found that three out of twenty promotional brochures studied contained data that was different from the original study on the effects of the drug.

7 Mar 2006

Artificial intelligence addresses the problem of confusing drug names

Was that Xanex or Xanax? Or maybe Zantac? If you're a health care professional you'd better know the difference--mistakes can be fatal.

7 Mar 2006

Mutant genes trigger AMD but may lighten the way to new treatments

According to new research in the U.S., the most common form of blindness in the elderly, age-related macular degeneration (AMD), can be attributed to just two genes which trigger the condition.

7 Mar 2006

SSRI use associated with increased risk for heart patients

In a surprising finding, patients with coronary artery disease who take commonly used antidepressant drugs may be at significantly higher risk of death, Duke University Medical Center researchers have found.

7 Mar 2006

New anti-drug program success

A newly-released study suggests that a well-designed in-school and community communication campaign really can dramatically cut marijuana and alcohol use among young teens.

7 Mar 2006

Extensive study of natalizumab

Scientists have completed an extensive study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005.

7 Mar 2006

5,000 rare diseases need drugs, but Europe only approves a handful each year

Only seven per cent of drug applications for treating people with rare diseases were approved in Europe between 2000 and 2004, despite the fact that there are currently more than 5,000 conditions needing medication.

6 Mar 2006

Next-generation drug development: risky and costly, but worth it

Generic drugs, which drive a $40 billion dollar generics industry expected to hit $60 billion by 2007, account for 53% of all prescriptions filled in the United States today.

6 Mar 2006

FDA gives greenlight for new treatment of head and neck cancer

The U.S. Food and Drug Administration has approved colon cancer drug Erbitux to treat head and neck cancer after results of a large clinical trial showed the drug prolonged survival by 20 months.

5 Mar 2006

Trials on MS drug Tysabri renews hope for sufferers

According to the results of two new trials the multiple sclerosis (MS) drug Tysabri significantly reduces the progression of the disease.

5 Mar 2006

Cannabis destroys cancer cells

Researchers investigating the role of cannabis in cancer therapy reveal it has the potential to destroy leukaemia cells, in a paper published in the March 2006 edition of Letters in Drug Design & Discovery.

1 Mar 2006

Treating orthopaedic trauma during pregnancy - most testing and treatments safe for fetuses and mothers

Pregnant women who suffer orthopaedic trauma should be diagnosed and stabilized in the same manner as any other patient, according to research published in the March 2006 issue of the Journal of the American Academy of Orthopaedic Surgeons.

1 Mar 2006

Rhodium quinones promise better drugs

By combining a common organic compound with a rare metal, a team of Brown University chemists has created a new class of molecules that have potentially important applications for the pharmaceutical, chemical and energy industries.

1 Mar 2006

Hydrogel scaffold materials used to create stable networks of blood vessels

Yale biomedical engineers have created an implantable system that can form and stabilize a functional network of fine blood vessels critical for supporting tissues in the body, according to a report in the Proceedings of the National Academy of Sciences.

1 Mar 2006