Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

FDA grants PMA for Pinnacle's Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber

Concordia Healthcare Corp. announced today that its subsidiary Pinnacle Biologics, Inc., a biopharmaceutical research and development company specializing in rare diseases, was granted U.S. Food and Drug Administration premarket supplemental approval (PMA) for its Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber.

26 Mar 2014

Inovio Pharmaceuticals receives three industry awards at World Vaccine Congress

Inovio Pharmaceuticals, Inc. today announced that it was recognized with three industry awards at the World Vaccine Congress, which is being held this week in Washington, D.C. The Vaccine Industry Excellence (ViE) Awards recognize outstanding vaccine advancements and achievements of therapeutic and preventive vaccine developers across the global industry as judged by a panel of global biotech industry stakeholders.

26 Mar 2014

FDA finds medical device recalls nearly doubled in 10 years

The Wall Street Journal says a report to be released today will spotlight the increasing number of problems.

24 Mar 2014

First Edition: March 21, 2014

Today's early morning highlights from the major news organizations, including a new examination of Ezekiel Emanuel's book about the crafting of the health law and President Obama's latest push to boost enrollment.

21 Mar 2014

Genetics may explain why some athletes are high functioning despite having hip abnormalities

Genetics may explain why some senior athletes are high functioning despite having one or both hip abnormalities typically associated with early onset osteoarthritis (OA): developmental dislocation of the hip (dysplasia), a loose hip joint; or femoroacetabular impingement (FAI), a condition in which the hip bones are abnormally shaped, according to new research presented today at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

11 Mar 2014

Scientific Statement details latest evidence for diagnosis and treatment of fibromuscular dysplasia

A vascular disease called fibromuscular dysplasia, which can cause high blood pressure, kidney failure, stroke and other symptoms -- mostly in women -- is "poorly understood by many healthcare providers," according to a Scientific Statement from the American Heart Association.

27 Feb 2014

Addition of confocal laser endomicroscopy to HDWLE improves diagnosis of Barrett's esophagus

New research shows that the addition of confocal laser endomicroscopy to high-definition white-light endoscopy enables improved real-time endoscopic diagnosis of Barrett's esophagus dysplasia (neoplastic tissue) by using targeted biopsies of abnormal mucosa to reduce unnecessary mucosal biopsies and potentially reduce costs.

20 Feb 2014

Researchers evaluate feasibility of using stem cell therapies on preterm infants to treat BPD

Advances in neonatal care for very preterm infants have greatly increased the chances of survival for these fragile infants. However, preterm infants have an increased risk of developing bronchopulmonary dysplasia (BPD), a serious lung disease, which is a major cause of death and lifelong complications.

6 Feb 2014

Gene therapies correct three forms of retinal degenerative diseases

Gene therapies developed by University of Pennsylvania School of Veterinary Medicine researchers have worked to correct different forms of blindness. While effective, the downside to these approaches to vision rescue is that each disease requires its own form of gene therapy to correct the particular genetic mutation involved, a time consuming and complex process.

17 Jan 2014

More standardised methods needed for extemporaneous preparation of paediatric medicines

More standardised methods are needed for the extemporaneous preparation of paediatric medicines, indicates a doctoral dissertation examined at the University of Eastern Finland. Hospital pharmacies modify adult medicines for children when there are no suitable paediatric medicines available. Medicines intended for adults can be modified for children into oral suspensions, oral powders or capsules the contents of which are emptied for use.

9 Jan 2014

Ikaria shareholders to sell Commercial Business to Madison Dearborn Partners

Ikaria, Inc., a critical care company focused on developing and commercializing innovative therapies designed to address the significant needs of critically ill patients, announced today that its investor group and employee shareholders have reached a definitive agreement to sell the Commercial Business to Madison Dearborn Partners in a transaction valued at approximately $1.6 billion.

26 Dec 2013

Concordia Healthcare acquires Pinnacle Biologics

Concordia Healthcare Corp., an integrated, specialty healthcare company focused on the acquisition of legacy pharmaceutical products and medical devices and the acquisition and/or development of orphan drugs, announced today that it has acquired Pinnacle Biologics, Inc., a U.S.-based biopharmaceutical company specializing in legacy pharmaceuticals which have the potential for development as orphan drugs to treat cancer indications in addition to those for which they have previously been approved.

24 Dec 2013

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Inovio Pharmaceuticals, Inc. announced today that preclinical testing of a DNA synthetic vaccine for the virulent Middle East Respiratory Syndrome coronavirus (MERS) induced robust and durable immune responses, demonstrating the potential for a SynCon DNA vaccine to prevent and treat this deadly virus.

20 Nov 2013

FDA grants Orphan Drug Designation to Advaxis' ADXS-HPV for HPV-associated head and neck cancer

Advaxis, Inc.,, a leader in developing the next generation of cancer immunotherapies, announced that it has been granted Orphan Drug Designation from the U.S. Food and Drug Administration Office of Orphan Products Development for ADXS-HPV, its lead drug candidate, for the treatment of human papillomavirus-associated head and neck cancer.

6 Nov 2013

EZH2 protein may aid prognostication in resected NSCLC

A protein called “enhancer of zeste homolog-2” is frequently expressed in non-small-cell lung cancer and may have prognostic value following surgical resection, US researchers believe.

30 Oct 2013

CEL-SCI, Ergomed To Co-Develop Head And Neck Cancer Candidate As Potential HPV Treatment

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16 Oct 2013

CEL-SCI, Ergomed To Co-Develop Head And Neck Cancer Candidate As Potential HPV Treatment

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15 Oct 2013

Researchers receive grant to improve outcomes for preterm infants who struggle to take first breaths

Monash University researchers have received a prestigious National Institutes of Health (NIH) project grant to find ways to improve outcomes for very preterm infants who struggle to take their first breaths.

10 Oct 2013

Edimer doses first XLHED-affected neonate in Phase 2 trial of EDI200

Edimer Pharmaceuticals, a biotechnology company focused on developing an innovative therapy for the rare genetic disorder X-linked Hypohidrotic Ectodermal Dysplasia (XLHED), today announced the enrollment and completed dosing of the first XLHED-affected neonate in a Phase 2 trial of EDI200, the company's novel, proprietary, recombinant protein.

9 Oct 2013

Radiofrequency ablation leads to remission of dysplastic Barrett's esophagus

Radiofrequency ablation (RFA) leads to remission for 91 percent of patients with dysplastic Barrett's esophagus, according to new figures published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

3 Oct 2013

Dysplasia News and Research

FDA grants PMA for Pinnacle's Optiguide DCYL700 Fiber Optic Diffuser Series flexible fiber

Inovio Pharmaceuticals receives three industry awards at World Vaccine Congress

FDA finds medical device recalls nearly doubled in 10 years

First Edition: March 21, 2014

Genetics may explain why some athletes are high functioning despite having hip abnormalities

Scientific Statement details latest evidence for diagnosis and treatment of fibromuscular dysplasia

Addition of confocal laser endomicroscopy to HDWLE improves diagnosis of Barrett's esophagus

Researchers evaluate feasibility of using stem cell therapies on preterm infants to treat BPD

Gene therapies correct three forms of retinal degenerative diseases

More standardised methods needed for extemporaneous preparation of paediatric medicines

Ikaria shareholders to sell Commercial Business to Madison Dearborn Partners

Concordia Healthcare acquires Pinnacle Biologics

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

FDA grants Orphan Drug Designation to Advaxis' ADXS-HPV for HPV-associated head and neck cancer

EZH2 protein may aid prognostication in resected NSCLC

CEL-SCI, Ergomed To Co-Develop Head And Neck Cancer Candidate As Potential HPV Treatment

CEL-SCI, Ergomed To Co-Develop Head And Neck Cancer Candidate As Potential HPV Treatment

Researchers receive grant to improve outcomes for preterm infants who struggle to take first breaths

Edimer doses first XLHED-affected neonate in Phase 2 trial of EDI200

Radiofrequency ablation leads to remission of dysplastic Barrett's esophagus

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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