Efficacy News and Research

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Comparison of antiretroviral therapies shows that tenofovir DF and stavudine are equally effective

Results from a three year double-blinded trial which compared antiretroviral therapies show that the combination regimens of tenofovir DF and stavudine, are equally effective, though tenofovir DF has more favorable outcomes with respect to cholesterol levels and the nervous system.

11 Jul 2004

Nevirapine effective in reducing the risk of transmission of HIV at birth

A drug called nevirapine has been shown to be effective in reducing the risk of transmission of HIV at birth, but combination therapy of nevirapine and zidovudine does not improve outcomes, according to a study published in the current HIV/AIDS Journal of the American Medical Association.

11 Jul 2004

Cheap AIDS drugs may help prevent HIV in babies in Thailand

Aids is one of the principal causes of infant mortality in many developing countries. Viral transmission takes place during pregnancy (in utero), at the moment of childbirth or even during breastfeeding.

10 Jul 2004

Antidepressants should not be avoided in treatment of pregnant women with severe depression

Antidepressants to treat from moderate to severe depression in pregnant women not only are relatively safe but necessary in many cases for the well-being of the mother and the baby

7 Jul 2004

Endo announces agreement With FDA for new trial design of oxymorphone extended-release tablets

Endo Pharmaceuticals Inc., a wholly owned subsidiary of Endo Pharmaceuticals Holdings Inc., today announced that it has reached agreement with the U.S. Food and Drug Administration

7 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes

Two new major studies suggest that anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes (ACS)

7 Jul 2004

NovoSeven may prove to be the first effective treatment for brain hemorrhage caused by stroke

Scientists from the UC Medical Center played a key role in developing what may prove to be the first effective treatment for brain hemorrhage caused by stroke.

5 Jul 2004

Medicine storage temperatures are too high

The recommended maximum storage and transit temperatures for most medications is 25°C and are set by the pharmaceutical manufacturers.

2 Jul 2004

Generic fixed-dose combinations (FDCs) of antiretrovirals are a key factor in access to treatment of HIV/AIDS infection in the developing world

Combination therapy with three generic antiretroviral drugs in a single tablet has been validated for the first time in an open clinical study in a developing country. Follow-up of 60 patients treated in Yaoundé, Cameroon, has demonstrated the excellent efficacy and safety of a generic fixed-dose combination.

2 Jul 2004

Access to HIV antiretroviral therapies in the developing world should be a major world health priority

One of the strategies adopted consists in utilizing combinations of fixed doses of generic antiretrovirals, involving three medicinal drugs of two different classes in the same tablet.

2 Jul 2004

Physical activity cuts risk of depression in children

Students who increase their physical activity during their middle-school years have fewer symptoms of depression, according to a new study.

1 Jul 2004

New drug application for cilansetron, an investigational product for the treatment of irritable bowel syndrome

Solvay Pharmaceuticals, Inc. has submitted a New Drug Application (NDA) for cilansetron, an investigational product being studied for the treatment of irritable bowel syndrome with diarrhea predominance (IBS-D), to the FDA on June 30, 2004.

1 Jul 2004

TUNA therapy results in significantly reduced erectile dysfunction

Comparing five-year results of Medtronic TUNA® Therapy (transurethral needle ablation) to surgery for 121 men in their mid-60s with lower urinary tract symptoms caused by an enlarged prostate, a team of urologists found that “for appropriately selected patients with bothersome voiding symptoms, TUNA is an attractive treatment option.”

1 Jul 2004

A Center for Human Genetics/Genomics has been established at the University of California

Established in UCSD Health Sciences, which includes the School of Medicine and School of Pharmacy and Pharmaceutical Sciences, the Center brings together UCSD faculty from multiple campus departments and schools including medicine, pharmacy, biology, biostatistics and mathematics.

30 Jun 2004

Efficacy News and Research

Comparison of antiretroviral therapies shows that tenofovir DF and stavudine are equally effective

Nevirapine effective in reducing the risk of transmission of HIV at birth

Cheap AIDS drugs may help prevent HIV in babies in Thailand

Antidepressants should not be avoided in treatment of pregnant women with severe depression

Endo announces agreement With FDA for new trial design of oxymorphone extended-release tablets

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes

NovoSeven may prove to be the first effective treatment for brain hemorrhage caused by stroke

Medicine storage temperatures are too high

Generic fixed-dose combinations (FDCs) of antiretrovirals are a key factor in access to treatment of HIV/AIDS infection in the developing world

Access to HIV antiretroviral therapies in the developing world should be a major world health priority

Physical activity cuts risk of depression in children

New drug application for cilansetron, an investigational product for the treatment of irritable bowel syndrome

TUNA therapy results in significantly reduced erectile dysfunction

A Center for Human Genetics/Genomics has been established at the University of California

Request for further evidence about the risks and benefits of the painkiller co-proxamol

Alcon updates filing status of RETAANE® new drug application

Duloxetine reduces stress urinary incontinence and improves quality of life for women

Exelixis files new drug application for a proprietary novel anticancer compound

Prince Charles has called for more research into the benefits of complementary therapies for cancer patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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