Electrolyte News and Research

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In chemistry, an electrolyte is any substance containing free ions that make the substance electrically conductive. The most typical electrolyte is an ionic solution, but molten electrolytes and solid electrolytes are also possible.

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Liquorice tea linked to hypertensive emergency – a case report

An 84-year-old man was admitted with hypertensive (high blood pressure) emergency after consuming a large amount of licorice tea.

28 May 2019

Pharmacists can undertake overall clinical responsibility for patients, shows study

The first evaluation of pharmacists based in accident and emergency departments has concluded that with additional clinical skills, they are able to take on overall clinical responsibility for patients.

19 Mar 2019

Penn researchers cure nine HCV patients following heart transplants from infected donors

Nine patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving heart transplants from deceased donors who were infected with the disease, according to a study published in the American Journal of Transplantation.

25 Feb 2019

Study offers new insights into mechanisms of changes in erythrocytes under stress

Various stress effects make an integral part of modern life, and their minimization is of particular relevance.

22 Feb 2019

Common acid reflux drugs tied to elevated risk for kidney disease

Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease.

19 Feb 2019

New technique using microneedles may mean rapid diagnoses of major illnesses

When people are in the early stages of an undiagnosed disease, immediate tests that lead to treatment are the best first steps. But a blood draw -- usually performed by a medical professional armed with an uncomfortably large needle -- might not be quickest, least painful or most effective method, according to new research.

3 Jan 2019

Novel lung-inspired design converts water into fuel

Scientists at Stanford University have designed an electrocatalytic mechanism that works like a mammalian lung to convert water into fuel. Their research, published December 20 in the journal Joule, could help existing clean energy technologies run more efficiently.

27 Dec 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

Multi-strain probiotic helps reduce chemotherapy-induced diarrhea in cancer patients

A high concentration of multi-strain probiotic helps to reduce mild to moderate episodes of chemotherapy-induced diarrhea in cancer patients, according to results of a phase II/III study in India.

22 Oct 2018

Experts call for more transparency about joint-venture ownership of dialysis clinics

Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on patient referrals and clinical outcomes.

4 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

Novel treatment for hairy cell leukemia approved by FDA

The U.S. Food and Drug Administration today approved Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell leukemia (HCL) who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration accepted its supplemental Biologics License Application for Sprycel (dasatinib) in combination with chemotherapy for the treatment of pediatric patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.

30 Aug 2018

Dehydration changes shape and activity of the brain, reduces task performance

When dehydration strikes, part of the brain can swell, neural signaling can intensify, and doing monotonous tasks can get harder.

21 Aug 2018

Young children are more vulnerable to climate-related health risks, shows study

Young children are far more vulnerable to climate-related disasters and the onus is on adults to provide the protection and care that children need, according to research by Columbia University's Mailman School of Public Health and Columbia University Irving Medical Center.

7 Aug 2018

Aggressive lowering of blood pressure reduces MCI risk, study shows

Significant reductions in the risk of mild cognitive impairment (MCI), and the combination of MCI and dementia, have been shown for the first time through aggressive lowering of systolic blood pressure in new research results from the federally-funded SPRINT MIND Study reported at the Alzheimer's Association International Conference 2018 in Chicago.

25 Jul 2018

Expert explains whether sparkling water is the same as plain water

The fruity, unique flavors and bright packaging of many seltzer and sparkling water brands have taken supermarkets by storm-;and many people say these bubbly beverages get them to drink more water every day.