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Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Scientists from the Britain's Medical Research Council Laboratory of Molecular Biology have for the first time, clearly pictured what the deposits typically seen in a person with Alzheimer’s disease look like. This is a breakthrough in neurodegenerative diseases. The latest study showing the structure of tau protein was published in the journal Nature.

5 Jul 2017

New study evaluates two additive manufacturing methods for producing fine or coarse textured implants

A new study evaluated two additive manufacturing methods for producing either fine or coarse textured titanium implants and compared the strength of bone integration, interlocking, and torque in rats given one or both types of the implants in the distal femurs.

30 Jun 2017

Study: Gadolinium may accumulate in brain tissues of patients without intracranial abnormalities

Minute traces of gadolinium, the contrast agent used to enhance MR images, are often retained in the brain tissue of patients years after undergoing MRI. Some studies have suggested this deposition was limited to patients with underlying brain pathology, such as a tumor or infection.

28 Jun 2017

Researchers shed light on molecular mechanisms of ovarian cancer metastasis

With 20,000 diagnoses each year, ovarian cancer is the ninth most common cancer and fifth leading cause of cancer death among women in the United States.

28 Jun 2017

Morgridge researchers reveal complex viral replication process in unprecedented detail

In the fight against the viruses that invade everyday life, seeing and understanding the battleground is essential. Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells.

27 Jun 2017

Novel Nanopsis technology quadruples magnification power of regular optical microscope

A British nanotech invention has revolutionized the humble optical microscope by quadrupling its magnification power to a level far beyond what could previously be achieved with visible light.

23 Jun 2017

Scientists reveal detailed snapshot of bacterial microcompartment shells

For the first time, scientists have visualized the fine details of bacterial microcompartment shells - the organisms' submicroscopic nanoreactors, which are comprised completely of protein.

22 Jun 2017

Researchers create new camera that can register fast processes in transparent specimens

Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the specimen.

22 Jun 2017

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Phasefocus provides a range of products and services based on its proprietary Ptychographic Quantitative Phase Imaging (QPI) technology to provide a wide range of analytical applications including label-free cell imaging and quantitative electron phase microscopy. Here, they report on the Light Microscopy Science Technology Platform at the Francis Crick Institute’s selection of the Livecyte® label-free cell analysis system.

From Phase Focus Limited 19 Jun 2017

Near-atomic resolution 3D snapshots show how key biological machine unfolds problematic proteins

Hand over hand. That's how new, near-atomic resolution, 3-D snapshots show that a key biological machine unfolds a ribbon of protein through its central channel.

16 Jun 2017

Altered virus could help more patients to become eligible for human gene therapy trials

For many patients, participating in gene therapy clinical trials isn't an option because their immune system recognizes and fights the helpful virus used for treatment.

13 Jun 2017

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Researchers from the Institute of Neurosciences of the UB and from IDIBAPS together with a team from the University Pierre and Marie Curie and the Institute du Fer à Moulin, published a study in Nature Communications, which demonstrates that the regulation in Pyk2, a protein-tyrosine kinase, causes alterations of the synaptic plasticity involved in memory tasks, associated with the hippocampus in mouse models of neurodegenerative diseases, such as Huntington's.

13 Jun 2017

Radiation therapy critical to treating brain tumors, but linked to significant adverse effects

Radiation therapy using high-energy particles, like x-rays or electron beams, is a common and critical component in successfully treating patients with brain tumors, but it is also associated with significant adverse effects, such as neuronal loss in adjacent healthy tissues.

9 Jun 2017

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

Calcium carbonate, or CaCO3, comprises more than 4% of the earth's crust. Its most common natural forms are chalk, limestone, and marble, produced by the sedimentation of the shells of small fossilized snails, shellfish, and coral over millions of years.

8 Jun 2017

Researchers capture first cryo-EM snapshots of key cellular receptor in action

Researchers at the University of Michigan, Stanford University and biotech company ConfometRx have captured the first cryo-electron microscopy snapshots of a key cellular receptor in action.

25 May 2017

Genetic sequencing reveals how Zika virus spread in the Americas

Genetic analysis of samples collected as the Zika virus (ZIKV) spread throughout the Americas after its introduction in 2013 or 2014 has shown that the virus circulated undetected for up to a year in some regions before it came to the attention of public health authorities.

24 May 2017

Researchers demonstrate multicolor 3D imaging of live mouse using compact Compton camera

Researchers invented a Compton camera of 580g which visualizes gamma rays of arbitrary energies, and succeeded in achieving a high-resolution, multicolor 3D molecular image of a live mouse administered with three different radioactive tracers in just 2 hours.

23 May 2017

Complex malaria vaccine protects monkeys against virulent parasite strains

Researchers from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite.

22 May 2017

Researchers identify antibodies that hold promise as Ebola treatments

The fight to contain the 2013-16 Ebola outbreak in West Africa was hampered by the lack of an effective treatment or vaccine. Researchers funded in part by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have studied the blood of an Ebola survivor, searching for human antibodies that might effectively treat not only people infected with Ebola virus, but those infected with related viruses as well.

18 May 2017

Study provides vital clues to counter superbug antibiotic resistance

An international study led by Monash University has discovered the molecular mechanism by which the potentially deadly superbug 'Golden Staph' evades antibiotic treatment, providing the first important clues on how to counter superbug antibiotic resistance.

16 May 2017