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Human pluripotent stem cells rely heavily on glycolysis to drive their metabolic activities

Human pluripotent stem cells, which can develop into any cell type in the body, rely heavily on glycolysis, or sugar fermentation, to drive their metabolic activities.

16 Nov 2011

Berkeley Lab, Bruker partner to develop and distribute new structural biology methods

Bruker Corporation and Lawrence Berkeley National Laboratory (Berkeley Lab) today announced a collaboration to develop and distribute new structural biology methods and tools to integrate Small-Angle X-ray Scattering (SAXS) with Nuclear Magnetic Resonance.

11 Nov 2011

ESPINA software tool allows to study brain structure in greater depth

Researchers at the UPM and CSIC, within the Cajal Blue Brain project, develop ESPINA, a new freeware software tool that allows to study the brain structure in greater depth.

10 Nov 2011

NovaSterilis reports significant findings from sterilization of absorbable suture study

NovaSterilis Inc. a leader in the development and commercialization of supercritical carbon dioxide (SCCO2) technology in collaboration with CC Chu Ph.D (Cornell) reports successful findings from research funded by a National Institutes of Health (NIH) phase l grant. These results meet the study goal to sterilize absorbable sutures to a sterility assurance level 10-6 (SAL6) without chemical or mechanical degradation. NovaSterilis intends to apply for phase II funding to develop the process ready for commercial application.

1 Nov 2011

Pharmasset initiates PSI-7977 Phase 3 program for HCV

Pharmasset, Inc. today announced the initiation of a Phase 3 program with the hepatitis C virus (HCV) nucleotide analog, PSI-7977. This pivotal program will evaluate a 12-week, all-oral, interferon-free regimen of PSI-7977 and ribavirin in patients with HCV, independent of viral genotype or their ability to take interferon therapy.

1 Nov 2011

NeCEN centre for electron microscopy to open in Leiden

NeCEN, a new high quality centre for electron microscopy, opens its doors in Leiden on October 27th. NeCEN has two of the most advanced cryo-transmission electron microscopes worldwide.

24 Oct 2011

Complexities of DNA repair

An international team of scientists led by UC Davis researchers has discovered that DNA repair in cancer cells is not a one-way street as previously believed. Their findings show instead that recombination, an important DNA repair process, has a self-correcting mechanism that allows DNA to make a virtual u-turn and start over.

24 Oct 2011

Critical migrating neurons in the human brain decline during infancy

José Manuel García Verdugo, full professor of Cell Biology at University of Valencia, together with a University of California research team, has participated in the discovery of new pathways of neurons migrating from lateral ventricles to the prefrontal cortex. The work done in chidren at early ages reveals a new cell pathway which may increase the amount of neurons in regions important for cognitive tasks, emotional processes and spatial perception.

22 Oct 2011

Electron-beam sterilized dialysis membrane may increase risk of thrombocytopenia

Patients who had undergone hemodialysis using dialyzers that had been sterilized with the use of electron beams were more likely to develop thrombocytopenia, according to a study in the October 19 issue of JAMA.

19 Oct 2011

New book investigates what fuels the passion for science

On April 8, 1982, alone in a laboratory, chemist Dan Shechtman looked through an electron microscope and saw an impossible pattern. He had discovered quasicrystals. But his groundbreaking findings were rejected, even mocked, by the scientific establishment for years.

15 Oct 2011

Insight into how powerful anti-HIV antibody grabs hold of the virus

Researchers at The Scripps Research Institute have uncovered the surprising details of how a powerful anti-HIV antibody grabs hold of the virus. The findings, published in Science Express on October 13, 2011, highlight a major vulnerability of HIV and suggest a new target for vaccine development.

14 Oct 2011

NIH awards Salk Institute $4.5M to establish new Neuroscience Core Center

The National Institutes of Health has announced that the Salk Institute will receive $4.5 million to establish a Neuroscience Core Center, a new research center intended to accelerate brain research that lays the foundation for developing new ways to treat congenital brain defects and neurological diseases.

14 Oct 2011

Pharmasset adds two treatment arms to PSI-7977 ELECTRON trial on HCV

Pharmasset, Inc. announced today the addition of two treatment arms to the ELECTRON trial of PSI-7977, a nucleotide analog polymerase inhibitor, for the treatment of chronic hepatitis C.

10 Oct 2011

Microscopy with helium ions may greatly enhance both surface and sub-cellular imaging

The ability to obtain an accurate three-dimensional image of an intact cell is critical for unraveling the mysteries of cellular structure and function. However, for many years, tiny structures buried deep inside cells have been practically invisible to scientists due to a lack of microscopic techniques that achieve adequate resolution at the cell surface and through the entire depth of the cell.

4 Oct 2011

Two ACS members, editor of JACS to receive nation's highest honors in science and innovation

Peter J. Stang, Ph.D., editor of the Journal of the American Chemical Society (JACS), and American Chemical Society members Jacqueline K. Barton, Ph.D. and Rakesh Agrawal, Ph.D., are among 12 eminent researchers and inventors named by President Obama to receive the nation's highest honors in science and innovation.

30 Sep 2011

Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

Study examines effects of carbon nanoparticles on living cells

A study by researchers from the schools of science and medicine at Indiana University-Purdue University Indianapolis examines the effects of carbon nanoparticles (CNPs) on living cells. This work is among the first to study concentrations of these tiny particles that are low enough to mimic the actual exposure of an ordinary individual.

16 Sep 2011

Electron microscope reveals minute morphology of dendritic trees

Neurons in the brain play a role as an electric wire conveying an electrical signal. Because this electric wire is connected with various joints, various brain functions can occur. A neuron which has dendritic trees on it, receives the signals with many synapses located on those dendritic trees, and carries out functions by combining the received signals.

14 Sep 2011

IBN scientists harness ultrasmall peptides to repair spinal disc damage

New ultrasmall peptides that can be used as building blocks for a wide range of regenerative applications such as spinal disc replacement and cartilage repair have been developed by scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute. These peptides spontaneously assemble in water to form hydrogels, which resemble collagen, a major component of connective tissues found in cartilage, ligaments, tendons, bone and skin.

12 Sep 2011

Scientists invent new system that uses magnetism to purify hybrid nanoparticles

A team of Penn State University scientists has invented a new system that uses magnetism to purify hybrid nanoparticles -- structures that are composed of two or more kinds of materials in an extremely small particle that is visible only with an electron microscope.

8 Sep 2011