Embryonic Stem Cell News and Research

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Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants -- a transfer of blood stem cells from a healthy person to a patient in need.

21 May 2019

Scientists develop new test to examine a drug's embryotoxicity in cell cultures

Medications have to be safe for mothers-to-be and for their unborn children. Before the authorities will approve a new drug, it must be tested in animal trials on pregnant rodents and, as a rule, pregnant rabbits.

14 May 2019

Skin-related stem cells could be used to regenerate vital part of the nervous system

Neurodegenerative diseases like multiple sclerosis affect millions of people worldwide and occur when parts of the nervous system lose function over time.

7 May 2019

Two new epigenetic regulators maintain self-renewal of embryonic stem cells

Embryonic stem cells have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body.

19 Apr 2019

Nicotine could affect human embryonic development at the single-cell level

Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report February 28th in the journal Stem Cell Reports.

4 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

New protein complex helps embryonic stem cells to maintain their indefinite potential

Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down any particular path toward a type of tissue, they lose their unlimited potential.

12 Dec 2018

A new way to create customized mouse models for studying brain development

Scientists studying how genetics impact brain disease have long sought a better experimental model. Cultures of genetically-modified cell lines can reveal some clues to how certain genes influence the development of psychiatric disorders and brain cancers.

11 Oct 2018

Researchers grow stem cell-derived lung organoids that model human lung development

Researchers have now grown lung organoids from human embryonic stem cells that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture approximating that of human lungs.

11 Sep 2018

Scientists uncover reason for similarity between cells in malignant cancers and embryonic cells

Using just a microscope, Italian surgeon Francesco Durante was struck by the similarities between cells in the most malignant cancers and the embryonic cells of the organ in which the cancer originated.

9 Aug 2018

Stem cells can re-muscularize infarcts in macaque monkey hearts, study shows

Researchers at UW Medicine in Seattle have successfully used human stem cells to restore heart function in monkeys with heart failure. The findings suggest that the technique will be effective in patients with heart failure, the leading cause of death in the world.

3 Jul 2018

Researchers transplant retinal sheets derived from human embryonic stem cells in retinal degeneration mouse models

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT have developed new mouse models of retinal degeneration that enable transplantation of retinal sheets derived from human embryonic stem cells.

17 May 2018

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

First-in-human clinical trial of retinal implant to treat dry AMD

Age-related macular degeneration (AMD) affects more than 1.75 million individuals in the United States. Because the population is aging, that number will increase to almost 3 million by 2020. Between 80 and 90 percent of cases in this country are the dry version of the condition, for which no effective treatment exists.

5 Apr 2018

New trial to test stem cell-based retinal implant for dry age-related macular degeneration

Physicians and researchers at the USC Roski Eye Institute have collaborated with other California institutions to show that a first-in-kind stem cell-based retinal implant is feasible for use in people with advanced dry age-related macular degeneration.

4 Apr 2018

New discovery could accelerate clinical translation of stem cell-based therapies

A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.

23 Feb 2018

Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

The effects of Huntington’s disease can be seen as early as conception, finds new study

In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.

30 Jan 2018

Embryonic Stem Cell News and Research

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Scientists develop new test to examine a drug's embryotoxicity in cell cultures

Skin-related stem cells could be used to regenerate vital part of the nervous system

Two new epigenetic regulators maintain self-renewal of embryonic stem cells

Nicotine could affect human embryonic development at the single-cell level

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Newly developed stem cell technologies show promise for treating PD patients

New protein complex helps embryonic stem cells to maintain their indefinite potential

A new way to create customized mouse models for studying brain development

Researchers grow stem cell-derived lung organoids that model human lung development

Scientists uncover reason for similarity between cells in malignant cancers and embryonic cells

Stem cells can re-muscularize infarcts in macaque monkey hearts, study shows

Researchers transplant retinal sheets derived from human embryonic stem cells in retinal degeneration mouse models

Scientists use haploid stem cells to create an atlas of the human genome

Scientists use haploid stem cells to create an atlas of the human genome

First-in-human clinical trial of retinal implant to treat dry AMD

New trial to test stem cell-based retinal implant for dry age-related macular degeneration

New discovery could accelerate clinical translation of stem cell-based therapies

Using CRISPR To Produce Induced Pluripotent Stem Cells

The effects of Huntington’s disease can be seen as early as conception, finds new study

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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