Embryonic Stem Cells News and Research

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Researchers demonstrate improved culture of primate induced pluripotent stem cells

The following study transplanted iPSCs derived from two NHP species, chimpanzee and pigtailed macaque, into blastocysts from another NHP species – the rhesus macaque.

1 Sep 2022

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial mutations to observe these tiny organelles.

30 Aug 2022

Mouse embryoids offer a promising model system to spur research into embryonic development and disease

Scientists funded in part by the National Institutes of Health have generated a mouse embryo model, or embryoid, that develops beyond neurulation—formation of the neural tube, which gives rise to the central nervous system—and closely mirrors natural mouse embryos 8.5 days after fertilization.

25 Aug 2022

Scientists explore ex utero generation of post-gastrulation synthetic embryos

Researchers showed that post-gastrulation synthetic embryos (sEmbryos) could be synthesized outside the uterus using mouse naive embryonic stem cells (ESCs).

9 Aug 2022

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Researchers develop a genetically modified airway organoid system, which overcomes challenges related to natural variations in ACE2 levels

4 Aug 2022

A major breakthrough toward new treatments for Type 1 and Type 2 diabetes

A world-first study by Monash University, in Melbourne, Australia has discovered a pathway to the regeneration of insulin in pancreatic stem cells, a major breakthrough toward new therapies to treat Type 1 and Type 2 diabetes.

22 Jul 2022

First-of-its-kind roadmap reveals how stem cells become sensory interneurons

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons -; the cells that enable sensations like touch, pain and itch.

19 Jul 2022

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems.

14 Jun 2022

New research reveals a potent weapon against Parkinson's disease

Neurodegenerative diseases damage and destroy neurons, ravaging both mental and physical health. Parkinson's disease, which affects over 10 million people worldwide, is no exception.

11 May 2022

Sen. Orrin Hatch’s legacy tracks the GOP’s evolution on health

When it comes to health policy, former Utah Republican Sen. Orrin Hatch, who died April 23 at age 88, leaves a complex legacy of major legislative achievements, changing positions, compromises, and fierce opposition.

28 Apr 2022

Study shows how cells use octopus-like tentacles to move around the body

With help from the best tweezers in the world a team of researchers from the University of Copenhagen has shed new light on a fundamental mechanism in all living cells that helps them explore their surroundings and even invade tissue.

28 Mar 2022

Using CRISPR/Cas to develop biosafety materials

Researchers discuss the use of the highly efficient CRISPR/Cas technologies to identify viral genome sequences for biosafety purposes.

21 Mar 2022

RNA-chopping enzyme Dicer stabilizes mammalian chromosomes with the help of BRD4 activator

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether.

17 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

New stem cell model could help map out the key genomic changes during early development

Researchers from the Babraham Institute have today published their latest work in the journal Cell Stem Cell describing a new subset of human embryonic stem cells that closely resemble the cells present at the genomic 'wake up call' of the 8-cell embryo stage in humans.

24 Feb 2022

CD91 receptor promotes SARS-CoV-2 infection

researchers find that LRP1/CD91 is a leading molecule in virus-host cell interactions that causes infection by many RNA viruses.

22 Feb 2022

Researchers develop 3D human spinal cord implants for treating paralyzed patients

For the first time in the world, researchers from Sagol Center for Regenerative Biotechnology at Tel Aviv University have engineered 3D human spinal cord tissues and implanted them in lab model with long-term chronic paralysis.

7 Feb 2022

Researchers generate a complex kidney-like 3D tissue in the lab

A research team based in Kumamoto University (Japan) has created complex 3D kidney tissue in the lab solely from cultured mouse embryonic stem (ES) cells.

1 Feb 2022

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

A protein known as Lefty pumps the brakes as human embryos begin to differentiate into the bones, soft tissues and organs that make us.

25 Jan 2022

Fast-tracked ruling on abortion won’t wait for ‘hearts and minds’ to change

When he was running for president in 1999, George W. Bush, then governor of Texas, famously fended off the strong anti-abortion wing of his party by suggesting the country ought not consider banning abortion until public opinion shifted further in that direction. "Laws are changed as minds are persuaded," he said.

21 Jan 2022