Encephalopathy News and Research

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Largest study finds CTE in 6% of athletes and non-athletes

Nearly 6% of athletes and non-athletes were found to have the neurodegenerative disorder chronic traumatic encephalopathy in the largest, and broadest, study conducted of the disease to date.

23 Jun 2019

New swine model helps scientists to better understand human brain

For the first time, researchers in the University of Georgia's Regenerative Bioscience Center have used an imaging method normally reserved for humans to analyze brain activity in live agricultural swine models, and they have discovered that pig brains are even better platforms than previously thought for the study of human neurological conditions such as Alzheimer's and Parkinson's.

21 Jun 2019

Dietary supplement improves neuronal function of a patient with atypical Rett syndrome

A multicentric translational research study carried out by groups of the Bellvitge Biomedical Research Institute, Sant Joan de Déu Hospital, the University of Barcelona, Hospital Clínic, the University of Vic, Sant Pau i la Santa Creu Hospital, the Rare Diseases Networking Biomedical Research Centre and the Commissariat à l'Énergie Atomique, has demonstrated the potential of the amino acid L-serine - administered as a dietary supplement - to improve the neuronal function of a patient with a mutation of glutamate receptors associated with atypical Rett syndrome with severe encephalopathy.

19 Jun 2019

Post-stroke headache in children may be a risk factor for stroke recurrence

A new study has found a high incidence of headaches in pediatric stroke survivors and identified a possible association between post-stroke headache and stroke recurrence.

12 Jun 2019

Researchers develop new gene-targeted approach to study chronic wasting disease in mice

Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect humans.

12 Jun 2019

Neurological Side Effects of CAR T-Cell Therapy Revealed

Researchers at Brigham and Women’s Hospital quantified the neurological symptoms associated with CAR T-cell therapy and found that 77 percent of patients receiving the treatment experienced at least one neurological side effect.

16 May 2019

Examining the Long-term Effects of Concussion in Sport

An interview with The Drake Foundation, discussing the short and long-term effects of concussions obtained during contact sports such as football and rugby.

10 May 2019

New type of dementia is '100 times more common' than ALS

Physicians have defined a new form of dementia that may be more common than Alzheimer’s disease. The condition, named LATE, affects a different part of the brain.

1 May 2019

Researchers define brain disorder that mimics symptoms of Alzheimer's disease

A brain disorder that mimics symptoms of Alzheimer's disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition.

30 Apr 2019

BUSM receives $4.9 million MLSC grant to accelerate development of new brain imaging techniques

Boston University School of Medicine today announced that it had received a $4.9 million grant from the Massachusetts Life Sciences Center to create a state-of the-art facility to accelerate development of novel brain imaging techniques to track subtle changes in the brain after neurotrauma.

30 Apr 2019

Measuring biomarkers in blood may help pinpoint newborns with HIE

Measuring a number of biomarkers over time that are produced as the body responds to inflammation and injury may help to pinpoint newborns who are more vulnerable to suffering lasting brain injury due to disrupted oxygen delivery and blood flow, according to research presented during the Pediatric Academic Societies 2019 Annual Meeting.

27 Apr 2019

Lower heart rate variability linked to autonomic manifestations of stress in newborns with HIE

In newborns with hypoxic-ischemic encephalopathy, lower heart rate variability correlates with autonomic manifestations of stress shortly after birth, underscoring the value of this biomarker, according to Children's research presented during the Pediatric Academic Societies 2019 Annual Meeting.

27 Apr 2019

New study aims to determine underlying etiology of seizures and reduce morbidities in children

A new study aims to determine the underlying etiology of seizures and help to target therapy, improve control of seizures, and potentially reduce morbidities in children.

27 Apr 2019

Researchers use experimental PET to detect abnormal tau in brains of living former NFL players

Using an experimental positron emission tomography scan, researchers have found elevated amounts of abnormal tau protein in brain regions players with cognitive, mood and behavior symptoms.

11 Apr 2019

Mild cognitive impairment may be present in early stages of kidney disease

The link between brain dysfunction and advanced kidney disease was first noted in 1930, so it is not a new finding.

10 Apr 2019

FDA approves new drug to treat adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Mayzent (siponimod) tablets to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.

27 Mar 2019

Hidden differences between pathology of CTE and Alzheimer's disease discovered

An international team of scientists at Indiana University School of Medicine, University of Kansas and the U.K. Medical Research Council have dismantled the belief that Alzheimer's disease and Chronic Traumatic Encephalopathy have identical pathology.

22 Mar 2019

Researchers define pathway that helps us make antibodies

Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.

13 Mar 2019

New AI platform detects neurodegenerative diseases in brain tissue samples

Researchers have developed an artificial intelligence platform to detect a range of neurodegenerative disease in human brain tissue samples, including Alzheimer's disease and chronic traumatic encephalopathy, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published in the Nature medical journal Laboratory Investigation.

5 Mar 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019