Endometrial Cancer News and Research

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Understanding obesity-cancer link to develop effective prevention strategies

In 2012, about 28,000 new cases of cancer in men (3.5%) and 72,000 in women (9.5%) were due to overweight or obesity in the United States alone. There is an urgent need for research that focuses on the cancer-promoting effects of obesity as it's the leading preventable cause of cancer for women and the second for men.

1 Nov 2017

New insights on seriousness of postmenopausal bleeding

If you're postmenopausal, you shouldn't be bleeding. The very definition of menopause is having gone more than 12 months without a period. So if you're still bleeding, something is wrong. Determining the seriousness of the problem and treating it, is not always evident.

11 Oct 2017

Endocrine Society expresses concerns that federal rule will reduce women's access to birth control

The Endocrine Society expressed concerns Friday with the presidential administration's new rules that would scale back the Affordable Care Act's contraception coverage mandate.

9 Oct 2017

Bariatric surgery linked to reduced risk of cancer for severely obese patients

Severely obese patients who undergo bariatric surgery lower their risk of developing cancer by at least a third, according to a University of Cincinnati College of Medicine researcher leading a large retrospective cohort study of patients in the western United States.

5 Oct 2017

Study may lead to new therapy options for treatment resistant, relapsed endometrial cancer

A team of Cleveland Clinic researchers have discovered a key pathway that leads to recurrence and treatment resistance in endometrial cancer, providing the potential for much needed new therapies for women with limited options.

24 Aug 2017

Vaginal estrogens do not increase cancer, cardiovascular disease risk in post-menopausal women

Women who have gone through menopause and who have been using a vaginal form of estrogen therapy do not have a higher risk of cardiovascular disease and cancer than women who have not been using any type of estrogen.

16 Aug 2017

Tiny biological nanoparticles offer enormous potential for diagnostic and therapeutic applications

Exosomes - tiny biological nanoparticles which transfer information between cells - offer significant potential in detecting and treating disease, the most comprehensive overview so far of research in the field has concluded.

23 Jun 2017

Researchers identify DNA repair deficiency in many types of solid tumors

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

18 May 2017

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.

16 May 2017

KU Leuven researchers grow three-dimensional cultures of the uterus' inner lining in a dish

Scientists at KU Leuven, Belgium, have succeeded in growing three-dimensional cultures of the endometrium, the uterus' inner lining, in a dish.

25 Apr 2017

Scientists grow womb lining models that could shed light on early pregnancy events

Scientists from the University of Cambridge have grown miniature functional models of the womb lining in culture, representing a major step forwards in the study of early-stage pregnancy and conditions such as endometriosis.

11 Apr 2017

Miniature models of ‘womb lining’ could provide insights into early pregnancy and menstrual cycle

Scientists at the University of Cambridge have succeeded in growing miniature functional models of the lining of the womb (uterus) in culture.

10 Apr 2017

Scientists uncover how tumor cells can switch disguises to spread easily around the body

Scientists have uncovered how tumor cells in aggressive uterine cancer can switch disguises and spread so quickly to other parts of the body.

30 Mar 2017

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in Cancer Discovery.

3 Mar 2017

Study identifies sentinel-lymph-node mapping as safe, accurate way to stage endometrial cancer

Emma Rossi, MD, in the UNC Department of Obstetric and Gynecology's Division of Gynecologic Oncology, has published a study in Lancet Oncology online that identifies sentinel-lymph-node mapping as a safer and less-invasive method of staging endometrial cancer that is equally as accurate as the more traditional lymphadenectomy.

21 Feb 2017

Uterine microbiome study provides important insights into etiology of endometrial cancer

Endometrial cancer triggers remain elusive, despite continued research. But given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease.

6 Jan 2017

Mutations linked to endometrial cancer can be found in uterine lavage fluid before cancer diagnosis

Mutations that have been linked to endometrial cancer can be found in the uterine lavage fluid of pre- and post-menopausal women both with and without detectable cancer, according to a study published in PLOS Medicine by John Martignetti, MD, PhD of the Icahn School of Medicine at Mount Sinai and colleagues.

30 Dec 2016

Mutations linked to endometrial cancer can be detected in uterine lavage fluid, study reveals

Mutations that have been linked to endometrial cancer can be found in the uterine lavage fluid of pre- and post-menopausal women both with and without detectable cancer, according to a study published in PLOS Medicine by John Martignetti from the Icahn School of Medicine at Mount Sinai, New York, USA, and colleagues.

28 Dec 2016

Regular NSAID use linked to increased risk of endometrial cancer mortality

Regular use of over-the-counter non-steroidal inflammatory drugs such as aspirin and ibuprofen is associated with an increased risk of dying in patients diagnosed with Type 1 endometrial cancers, according to a new population-based study led by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

20 Dec 2016

Surgery within first two weeks after diagnosis increases risk of death for some endometrial cancer patients

Delaying surgery after a diagnosis of uterine cancer can increase a women's risk of death, but operating too soon can be just as detrimental for some, Penn Medicine physicians report in a new study published in the American Journal of Obstetrics and Gynecology.

16 Dec 2016