Endoplasmic reticulum (ER) News and Research

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Johns Hopkins study highlights need for effective postpartum interventions for women with pregnancy complications

Citing an analysis of more than 26,000 Maryland Medicaid claims, Johns Hopkins researchers report evidence that poor women with recent complications during their pregnancies are using the emergency room at higher rates after delivery and may not be getting the postpartum care and follow-up they need to prevent further health problems.

29 Sep 2015

Scientists trace out intricate molecular pathway that may explain tamoxifen resistance in breast cancer patients

For reasons unknown, many patients with breast cancer treated with the estrogen receptor-blocking drug tamoxifen eventually become resistant to the treatment despite the fact that their cancer cells still have the estrogen receptor proteins that the drug normally targets.

24 Sep 2015

ER visits can reduce underage drinking and associated problems

The results of a five-year trial from faculty at the University of Michigan Injury Center found giving youth in the emergency department a short intervention during their visit decreased their alcohol consumption and problems related to drinking over the following year.

23 Sep 2015

New commercial EHRs increase potential for patient safety hazards

Even after emergency physicians had acclimated to a new commercial electronic health record (EHR), they increased their tasks performed per minute by nearly 12 percent, increasing the potential for patient safety hazards.

23 Sep 2015

UCI scientists find potential biomarker for diagnosing certain forms of autism

By identifying a key signaling defect within a specific membrane structure in all cells, University of California, Irvine researchers believe, they have found both a possible reliable biomarker for diagnosing certain forms of autism and a potential therapeutic target.

22 Sep 2015

Satellite DNA plays vital regulatory role in how organisms adapt to environmental changes

A team of geneticists led by Prof. Đurđica Ugarković of the Croatian Ruđer Bošković Institute have for the first time proved that satellite DNA plays an important regulatory role in how organisms adapt to stressful changes in their environment. These results could in the future help scientists explain how an organism successfully survives stress.

21 Sep 2015

Study: Neighborhood factors do not influence EMS use for acute stroke as strongly as individual factors do

Neighborhood factors do not influence the use of emergency medical services (EMS) for stroke as strongly as individual factors do, despite earlier indications that socio-demographic characteristics of the neighborhood explain low rates of EMS activation for this life-threatening emergency.

21 Sep 2015

Scientists discover new mechanism that protects brain stem cells against aging-induced damage

Neural stem cells generate new neurons throughout life in the mammalian brain. However, with advancing age the potential for regeneration in the brain dramatically declines.

18 Sep 2015

HemoPalm technology can benefit physicians and first responders

Each year, hundreds of thousands of patients come to the ER experiencing life threatening events such as possible carbon monoxide poisoning or heart attacks, attending doctors in a medical institution rely on the current standard blood gas analyzers to diagnose the oxygen-carrying capabilities of blood, blood gases and electrolytes.

16 Sep 2015

AcelRx's ARX-04 meets primary and secondary endpoints in Phase 3 trial

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, today announced that ARX-04 (sufentanil sublingual tablet, 30 mcg) met primary and secondary endpoints in a multi-center, double-blind, placebo-controlled Phase 3 trial (SAP301) designed to study the short-term treatment of patients with moderate-to-severe acute pain following ambulatory abdominal surgery.

9 Sep 2015

Study: Wildfire smoke exposure associated with increased visits to ER for asthma

Researchers who analyzed data from the 2006-2007 wildfires in Australia found that exposure to wildfire smoke was linked to increased visits to hospital emergency departments for asthma.

9 Sep 2015

Egalet to present scientific data on SPRIX Nasal Spray at Painweek 2015

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on discovering, developing, and commercializing innovative pain treatments, today announced that researchers will be presenting scientific data on SPRIX (ketorolac tromethamine) Nasal Spray, Egalet-001, an abuse-deterrent, extended-release, oral morphine product candidate, and Egalet-002, an abuse-deterrent, extended-release, oral oxycodone product in development, at PainWeek 2015 to be held September 8 to 12 in Las Vegas, Nevada.

1 Sep 2015

SLU study finds that length of stay in ED makes no real difference in mortality of trauma patient

The amount of time a trauma patient stays in the emergency department (ED) makes no real difference in the patient's mortality, researchers at Saint Louis University found in a recent study.

28 Aug 2015

Education can empower clinicians to safely prescribe opioids for chronic pain sufferers

Educating clinicians on how to safely prescribe opioids can help decrease opioid misuse among chronic pain sufferers.

27 Aug 2015

MTG Biotherapeutics' MTG-201 granted FDA Orphan Drug Designation for malignant mesothelioma treatment

MTG Biotherapeutics, an immuno-oncology company developing novel therapeutics for the treatment of cancer, today announced that the US Food and Drug Administration has granted Orphan Drug Designation for MTG-201, an advanced biologic therapy targeting Dickkopf-3 gene defects in various cancers, for the treatment of malignant mesothelioma.

23 Aug 2015

Neighbors Emergency Center announces opening of new El Paso, Texas center

Neighbors Emergency Center announces today the opening of its new El Paso, Texas center. The emergency center location will be open to receive patients at 6:00 pm MDT on Tuesday, August 18, 2015.

18 Aug 2015

Many older adults tend to overestimate their mobility

Many seniors who visit emergency departments require more assistance with physical tasks than they think they do, which may lead to hospital readmission later on. The results of the study were published online Friday in Annals of Emergency Medicine ("Self-Reported vs. Performance-Based Assessments of a Simple Mobility Task Among Older Adults in the Emergency Department").

7 Aug 2015