Endothelial cell News and Research

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Researchers discover new mechanism responsible for blood vessel tumors that cause facial deformities

Researchers have discovered a new mechanism responsible for the growth of blood vessel tumors that can cause facial deformities in infants and young children, paving the way for an antibody-based treatment to remove cells that fuel the tumors’ growth.

5 Oct 2004

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Genaera Corporation has announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to squalamine, an intravenously administered, first in class, small molecule anti-angiogenic drug for the treatment of "wet" age-related macular degeneration (AMD).

4 Oct 2004

Potential stem cells treatment for retinitis pigmentosa and other retinal degenerations

A team of researchers from The Scripps Research Institute was able to preserve visual function in mice that were genetically predisposed to developing a profound degenerative disease that destroys their retinas.

16 Sep 2004

Drug combo may have a greater impact on cancer development

Cancer researchers have long suggested that new targeted drugs may work best when paired with other therapies. In a new study published today in Cancer Research, scientists have taken some of the first steps to demonstrate this synergy in mouse and cell line models.

16 Sep 2004

FDA approves permanently implanted lens as an alternative to contact lenses or laser surgery

The Food and Drug Administration (FDA) has approved a plastic lens that is permanently implanted into the eye to correct moderate to severe nearsightedness.

14 Sep 2004

Study sheds light on lymphedema

A study from the Ludwig Institute for Cancer Research Affiliate Center at the University of Helsinki in Finland has shed light on the development of lymphatic vasculature and valves, and may help to develop better treatments for lymphedema.

23 Aug 2004

Effects of oxidative stress on atherosclerosis

Heart disease and stroke are the first and third leading causes of death among men and women in the United States and account for 40 percent of all mortalities, according to the Centers for Disease Control and Prevention.

9 Aug 2004

Congenital heart disease (CHD) is a leading cause of mortality in children worldwide

Congenital heart disease (CHD) is a leading cause of mortality in children worldwide. According to the American Heart Association, Congenital cardiovascular defects are present in about one percent of live births and are the most common malformations in newborns.

12 Jul 2004

Kaposi sarcoma virus common in people who are HIV positive turns lymph vessel cells into a cancer

A virus turns lymph vessel cells into a cancer that affects people with weakened immune systems, according to research published today in Nature Genetics.

28 Jun 2004

First-ever microfluidic BioMEMS device to study the mechanisms of cell migration and deformation

Cancer cells have the ability to invade blood vessels and find their way into the bloodstream. Once there, these infected cells can easily travel to other parts of the body and attack healthy organs.

25 Jun 2004

Exercise helps overweight men with erectile dysfunction

Erectile dysfunction is known to decrease the quality of life in men, and may affect as many as 30 million men in the United States alone, according to the new study. In a previous study, moderate-to-severe erectile dysfunction was reported by 12 percent of men below the age of 59; 22 percent of men aged 60 to 69 years; and 30 percent of 69 years and older.

22 Jun 2004

Potential new strategy for blocking tumor growth

Targeting a master molecule that helps cancer cells survive when blood oxygen levels are low may offer a potentially powerful strategy for blocking tumor growth, say researchers at The University of Texas M. D. Anderson Cancer Center.

16 Jun 2004

Link between oral bacterium and premature babies

For years, scientists have noticed a particular oral bacterium can be found in the amniotic fluid of about 20 percent of women with premature babies.

27 May 2004

Australian researchers identify potential target to fight tumours

Dr Guishui Zhang and Associate Professor Levon Khachigian, from the Centre for Vascular Research, and Dr Nick Di Girolamo of the School of Medical Sciences were part of a team which suppressed a protein in the cells lining blood vessels.

14 May 2004

Cholesterol-lowering drugs could treat multiple sclerosis

Drug treatments for MS are expensive and only partially effective. Recent knowledge that statins promote an anti-inflammatory response from the immune system suggest a potential in the treatment of MS.

13 May 2004

Natural compound in snake venom for treatment of malignant tumours

Researchers at the University of South Australia have made a major discovery using a natural compound in snake venom that shows very promising anti-cancer effects. The compound works by activating the destruction of cells which make up the blood vessels that supply nutrients to tumours, according to Associate Professor Tony Woods from UniSA’s School of Pharmaceutical, Molecular and Biomedical Sciences.

30 Mar 2004

New treatment for heart attacks

A team led by scientists at The Scripps Research Institute has developed a potential new treatment for heart attacks. The therapy inhibits fluid leakage from cardiac blood vessels following a heart attack and thereby significantly prevents long-term heart damage and improves survival.

22 Mar 2004